Exposure-Integrated Risk Prioritization of Legacy and Emerging PFAS: A Case Study of a Major River Basin in South Korea via High-Resolution Mass Spectrometry
This study pioneers an exposure-integrated risk prioritization framework for the Geum River basin in South Korea by combining high-resolution mass spectrometry with QSAR-based hazard assessment, revealing that while long-chain PFAS possess the highest intrinsic toxicity, short-chain variants like PFBS and PFHxA along with PFOA constitute the greatest management priority due to their widespread environmental loading.