Supervised Metric Regularization Through Alternating Optimization for Multi-Regime Physics-Informed Neural Networks

This paper introduces Topology-Aware PINNs (TAPINN), a novel framework that employs supervised metric regularization and alternating optimization to effectively resolve spectral bias and mode collapse in multi-regime physics-informed neural networks, achieving superior convergence stability and accuracy compared to standard and hypernetwork-based baselines.

Enzo Nicolas Spotorno, Josafat Ribeiro Leal, Antonio Augusto Frohlich2026-03-06🔬 physics

Empirical Stability Analysis of Kolmogorov-Arnold Networks in Hard-Constrained Recurrent Physics-Informed Discovery

This paper empirically demonstrates that while Kolmogorov-Arnold Networks (KANs) can compete with MLPs on simple univariate residuals in hard-constrained recurrent physics-informed architectures, they suffer from severe hyperparameter fragility, instability in deeper configurations, and consistent failure on multiplicative terms, ultimately revealing limitations in their additive inductive bias for modeling state coupling in oscillatory systems.

Enzo Nicolas Spotorno, Josafat Leal Filho, Antonio Augusto Medeiros Frohlich2026-03-06🔬 physics

SubQuad: Near-Quadratic-Free Structure Inference with Distribution-Balanced Objectives in Adaptive Receptor framework

SubQuad is an end-to-end pipeline that overcomes the computational and data imbalance bottlenecks in large-scale adaptive immune repertoire analysis by integrating near-subquadratic MinHash retrieval, GPU-accelerated affinity kernels, and fairness-constrained clustering to enable scalable, bias-aware discovery of clinically relevant clonotypes.

Rong Fu, Zijian Zhang, Kun Liu + 3 more2026-03-06💻 cs

Curriculum Learning for Efficient Chain-of-Thought Distillation via Structure-Aware Masking and GRPO

This paper proposes a three-stage curriculum learning framework that leverages structure-aware masking and Group Relative Policy Optimization (GRPO) to efficiently distill Chain-of-Thought reasoning into compact student models, achieving significant accuracy gains and output length reduction on GSM8K by progressively guiding the model from structural understanding to self-optimized brevity and targeted knowledge internalization.

Bowen Yu, Maolin Wang, Sheng Zhang + 7 more2026-03-06💻 cs

CityGuard: Graph-Aware Private Descriptors for Bias-Resilient Identity Search Across Urban Cameras

CityGuard is a privacy-preserving, graph-aware transformer framework that enables robust, bias-resilient person re-identification across distributed urban cameras by integrating dispersion-adaptive metric learning, spatially conditioned attention for coarse geometric alignment, and differentially private embeddings to balance retrieval accuracy with data protection.

Rong Fu, Yibo Meng, Jia Yee Tan + 5 more2026-03-06💻 cs

Inference-time optimization for experiment-grounded protein ensemble generation

This paper introduces a general inference-time optimization framework that generates experiment-grounded protein ensembles by optimizing latent representations and employing novel sampling schemes, thereby overcoming the limitations of current diffusion-based methods to produce thermodynamically plausible structures with improved agreement to experimental data while exposing vulnerabilities in existing confidence metrics.

Advaith Maddipatla, Anar Rzayev, Marco Pegoraro + 5 more2026-03-06💻 cs