Epidemiology is the study of how diseases spread through populations and what factors influence their patterns. Rather than focusing on individual patients, this field examines broader trends to identify outbreaks, track transmission, and guide public health decisions. By analyzing data on infection rates and risk factors, researchers work to prevent future health crises and protect communities worldwide.

On Gist.Science, we process every new preprint in this category directly from medRxiv to make these critical findings instantly accessible. For each study, we provide both a plain-language explanation for general readers and a detailed technical summary for specialists. This dual approach ensures that vital insights into disease dynamics are understood clearly and quickly by everyone who needs them.

Explore the latest research below to see how scientists are currently mapping disease trends and developing strategies to safeguard global health.

📊 epidemiology

Divergent Trends in Stroke and Ischemic Heart Disease Mortality and Disability in Western Sub-Saharan Africa Compared with Global Progress, 1990-2023

Between 1990 and 2023, Western Sub-Saharan Africa fell significantly behind global progress in reducing cardiovascular mortality, characterized by a modest decline in stroke deaths and a troubling reversal where ischemic heart disease mortality increased despite substantial socioeconomic development, primarily driven by uncontrolled hypertension and rising cardiometabolic risk factors.

Ankrah-Twumasi, P., Ofori, J. J. V., Pekyi-Boateng, P., Twerefour, Y., Sackey, D.2026-08-23
📊 epidemiology

Joint Heat and PM2.5 Exposure Across US Metropolitan Areas: Multi-Stressor Disparities, Historical Redlining, and a Multi-Metric Assessment Framework

This study introduces a novel multi-metric framework to assess joint heat and PM2.5 exposure across 48 US metropolitan areas, revealing that residents in historically redlined and predominantly Black neighborhoods face significantly higher risks of simultaneous extreme heat and air pollution compared to their White counterparts, even after adjusting for socioeconomic factors.

Mandalapu, S. V., Sharma, R., Pillarisetti, A.2026-08-23
📊 epidemiology

Rethinking respiratory disease forecasting: temporal heterogeneity between surveillance predictors and outcomes drives forecast instability

This study demonstrates that the unstable and seasonally variable relationships between diverse surveillance predictors and respiratory disease outcomes undermine the effectiveness of static forecasting models and long-term historical training, necessitating adaptive strategies and continual evaluation to improve forecast accuracy.

Topazian, H. M., Sheets, T. R., Gruninger, R. J., Kelley, J., LaCross, N., Samore, M. H., Lofgren, E., Keegan, L. T.2026-08-22
📊 epidemiology

Autistic traits and alcohol consumption through adolescence and young adulthood

This longitudinal study of the ALSPAC cohort reveals that while genetic liability for autism does not significantly influence alcohol consumption, higher levels of autistic traits are generally associated with lower drinking across most consumption levels, except among heavy drinkers where social communication differences correlate with increased alcohol use.

Page, S., Parker, R., Easey, K. E., Sedgewick, F., Rai, D., Stergiakouli, E.2026-08-21
📊 epidemiology

Infrastructure risk factors for leptospirosis transmission in urban informal settlements

This study utilized high-precision georeferenced mapping in Salvador, Brazil, to demonstrate that residents with leptospirosis exposure in urban informal settlements are significantly more likely to live near inadequate sewerage components, poorly maintained streets, and lower elevations, highlighting the critical role of specific infrastructure deficiencies in disease transmission.

Nascimento Silva, A. M., Santana, J. O., Machado, G. G., Souza, F. N., de Oliveira, D. S., Palma, F. A. G., dos Santos (…)2026-08-21
📊 epidemiology

Factors associated with rabies vaccination uptake among dog owners in Butaleja Town Council, Eastern Uganda: A cross-sectional study

This cross-sectional study in Butaleja, Uganda, reveals that while 57% of dog owners vaccinated at least one dog, overall coverage remained below the 70% herd immunity threshold due to significant barriers, identifying that older age, higher education, income, access to veterinary clinics, and community education are key factors associated with successful rabies vaccination uptake.

Hasahya, S., Kamukama, S., Lunkuse, S. M., Lubogo, D.2026-08-21
📊 epidemiology

Clinical Epidemiological Features and Risk Factor Weight Remodeling in Gallstone Patients on the Plateau

In a retrospective cohort study of gallstone patients at high altitude, the original hypothesis that BMI replaces sex as the core risk factor for cholecystitis was falsified, revealing instead that systolic blood pressure is the sole significant positive predictor while age exhibits an inverse association.

Wang, Z., Ren, G., Dang, Z., Su, W., Ma, Y., Li, P., Ji, D., Li, L., Gao, J.2026-08-21
📊 epidemiology

Effect of household boiling on ciprofloxacin and enrofloxacin residues in cow milk from Dhaka, Bangladesh: paired HPLC-UV screening and dietary exposure assessment

A study of 120 cow milk samples from Dhaka, Bangladesh, found that while 15 minutes of household boiling significantly reduced ciprofloxacin and enrofloxacin residue levels, it failed to bring the vast majority of contaminated samples below the EU maximum residue limit, leaving dietary exposure risks largely unchanged.

Ahmed, M., Asif, M. A., Rinky, F., Mostafa, M. G., Bhuiyan, M. N. I., Afrin, S., Ahmed, T., Rahman, A.2026-08-21
📊 epidemiology

Quantifying infection-relevant contact patterns among young children in childcare settings in the United States.

This study utilizes nationally representative childcare data to reconstruct daily contact patterns for young children in the United States, revealing that existing models significantly underestimate contacts in this age group and consequently misrepresent the frequency and impact of infectious disease outbreaks like measles.

Loo, S. L., Nande, A., Hill, A. L., Truelove, S.2026-08-21
📊 epidemiology

Identifying adverse experiences in childhood in the Born in Bradford Birth Cohort children

This study utilizing the Born in Bradford Birth Cohort data reveals that adverse childhood experiences are widespread, affecting nearly two-thirds of children by early adolescence, with prevalence varying significantly by ethnicity and maternal material deprivation, thereby highlighting the need for targeted early-years policies to address these disparities.

Lam, N., Wadman, R., Watmuff, A., Gilbody, S.2026-08-21