📄 Category

medicine

13396 papers

📄 medicine

Functional Independence in Community-Dwelling Older Adults: Associations with Nutritional Status, Depressive Symptoms, and Fall Risk

This cross-sectional study of 245 community-dwelling older adults in Türkiye found that nutritional status is the strongest predictor of functional independence, while depressive symptoms, fall risk, and older age are significant negative factors, underscoring the need for comprehensive geriatric assessments that integrate nutritional, psychological, and functional evaluations.

Funda Tuncer Sahin2026-10-23
📄 medicine

Comparison of curcumin-based chemotherapy-radiotherapy regimens containing paclitaxel, doxorubicin, or 10-hydroxycamptothecin in U87 glioma models

This study demonstrates that while curcumin combined with paclitaxel, doxorubicin, or 10-hydroxycamptothecin all enhance chemotherapy-radiotherapy efficacy against U87 glioma models, the specific chemotherapy agent significantly influences the treatment response, with the curcumin-10-hydroxycamptothecin combination showing the most promising results in reducing tumor burden.

haidong tian, Subing Li, Jiahao Zhang, jiadi Liu, huijun Guo, Zunqiang Zhao, Zheng Shi, Hongyan Li2026-10-23
📄 medicine

Seroprevalence of Hepatitis A, Hepatitis B, Hepatitis C, and HIV Among Patients Undergoing First Hemodialysis in the Emergency Department: A Retrospective Cross- Sectional Study

This retrospective cross-sectional study of 218 patients undergoing their first hemodialysis in an emergency department found a 47.2% seroprevalence of past Hepatitis A infection, 4.1% for Hepatitis B, and 3.7% for Hepatitis C, with no active HIV or acute viral infections detected, while identifying female gender as a significant risk factor for Hepatitis C positivity.

Şükran Köse, Cüneyt Arıkan, Erhan Can Başar, Yiğit Epik, Asya Yılmaz, Kıvanç Çapar, İrem Üner2026-10-23
📄 medicine

Effects of Early Alirocumab Plus Statin Therapy on Lipid Control and Vascular Endothelial Function After PCI in Patients With Coronary Artery Disease

In patients with coronary artery disease undergoing PCI, early combination therapy with alirocumab and statins achieved superior reductions in LDL-C, total cholesterol, and ApoB, along with improved vascular endothelial function and arterial elasticity, compared to statin monotherapy alone, without significant adverse effects on hepatic, renal, or muscle safety markers within 8 weeks.

Yixiong Qiao, Jiewen Lei, Yuwen Cao, Junbo Wei, Wenkun Bai, Junhong Zhou, Junxia Wu, Yongguang Li2026-10-23
📄 medicine

Preconception Metabolic Bariatric Surgery and Offspring Infant Growth Trajectories and Body Size from Birth to Age at School Entry: The POSIT Study

Although preconception metabolic bariatric surgery improves maternal health and reduces the risk of large-for-gestational-age births, it does not lower the risk of childhood obesity and may even increase the likelihood of severe obesity by age five compared to controls matched by pre-pregnancy BMI.

Jonathan Purnell, Janne Boone-Heinonen, Jiaxiao Shi, Sijia Qiu, Darios Getahun, Caryn Oshiro, Carmen Wong, Padma Koppolu (…)2026-10-23
📄 medicine

Antibacterial, antibiofilm, modulatory effects, pharmacokinetic profile, toxicity and molecular docking of Monarda fistulosa essential oil against Multidrug-Resistant Acinetobacter baumannii

This study demonstrates that *Monarda fistulosa* essential oil, primarily composed of geraniol, exhibits potent antibacterial and antibiofilm activities against multidrug-resistant *Acinetobacter baumannii*, acts synergistically with carbapenems to reduce required dosages, and possesses favorable pharmacokinetic and safety profiles for potential use as a phytotherapeutic adjuvant.

Marcílio Dimateus Lima Torres Martins, Pedro Henrique Lima Rodrigues, Francisca Lidiane Linhares Aguiar, Geovany Amorim (…)2026-10-23
📄 medicine

Prognostic heterogeneity within cognitive stages: a nationwide cohort study of everyday functional difficulties and mortality in 202,508 older adults

This nationwide cohort study of over 200,000 older adults demonstrates that everyday functional difficulties, specifically in rising, concentrating, understanding speech, and standing, significantly predict mortality risk within Clinical Dementia Rating stages, revealing that individuals with severe functional impairment at early cognitive stages face higher three-year mortality than those with no functional impairment at advanced stages.

Wen-Chou Chi, Tsan-Hon Liou, Wei-Ming Wang, Chia-Feng Yen, Hua-Fang Liao, Wen-Ni Wennie Huang2026-10-23
📄 medicine

Association of TLR8 Expression in Peripheral Blood Mononuclear Cells with Clinical and Histopathological Severity in IgA Nephropathy

This study demonstrates that elevated TLR8 expression in both peripheral blood mononuclear cells and renal tissue is significantly associated with increased clinical and histopathological severity, as well as higher galactose-deficient IgA1 levels, in patients with IgA nephropathy, suggesting its potential as a biomarker for disease severity.

Na Jiang, Qian Meng, Yingjie Cao2026-10-23
📄 medicine

Internal Exposure to Mycotoxins and Associated Nutritional Risk in Young Children Consuming Maize Porridge in South Kivu, Democratic Republic of Congo: A Pilot Biomonitoring Study

This pilot biomonitoring study in South Kivu, DRC, reveals that young children consuming maize porridge are exposed to multiple mycotoxins, with AFB1-lysine levels showing a significant positive association with stunting, highlighting the urgent need for integrated food safety and nutritional interventions.

Christus Cito Miderho, Lucy G. Njue, George O. Abong, Sarah De Saeger, An Chen, Yasmine Bader, Orphélie Lootens, Esther (…)2026-10-23