13396 papers
This paper outlines the protocol for a multicenter, randomized, double-blind, placebo-controlled trial in China designed to evaluate the efficacy and safety of fecal microbiota transplantation as an adjunctive therapy for improving symptoms and cognitive function in patients with non-treatment-resistant schizophrenia.
This study developed and validated a high-performance stacking survival ensemble model that utilizes intratumoral and peritumoral habitat radiomic features from routine preoperative multiparametric MRI to accurately predict disease-free survival and stratify risk in patients with early-stage cervical cancer.
This single-center case series demonstrates the feasibility and safety of platelet reactivity unit (PRU)-guided cangrelor therapy for endovascular reconstruction of traumatic internal carotid artery injuries in three adolescents, particularly when oral antiplatelet therapy is unreliable or interrupted, though larger prospective studies are needed to confirm these findings.
This qualitative systematic review of 125 studies reveals that physicians frequently encounter intersecting forms of discrimination from patients, colleagues, and institutions, which significantly harms their well-being and patient care quality while often remaining unreported due to fear and institutional barriers.
The study demonstrates that the novel inhibitor KDR2-2 effectively ameliorates radiation-induced brain injury by targeting the non-canonical HSP90β–VEGFR2 Y1214 signaling axis, showing superior efficacy over the standard treatment bevacizumab in reducing neurovascular dysfunction and neuroinflammation.
This paper presents two case reports of levonorgestrel-releasing intrauterine device migration in breastfeeding women—one symptomatic and one asymptomatic—to demonstrate that when transvaginal ultrasonography fails to visualize the device, an abdominopelvic radiograph is essential to confirm extrauterine migration and guide timely laparoscopic removal.
This cross-sectional study of 168 young healthcare professionals in Karachi found that daily smartphone use of four hours or more is significantly associated with a higher prevalence of back pain compared to shorter usage durations.
A cross-sectional study of 266 mothers at Federal Teaching Hospital Ido-Ekiti reveals that while awareness of exclusive breastfeeding is high (91%) and attitudes are generally positive (65.4%), actual practice stands at 63.9% and is significantly influenced by age and employment status, highlighting the need for targeted support to overcome existing challenges and improve rates.
This case report describes a rare instance of ethmoidal alveolar rhabdomyosarcoma with orbital extension in a 28-year-old adult, highlighting the diagnostic challenges posed by its non-specific presentation and emphasizing the critical role of histopathology, immunohistochemistry, and FOXO1 molecular testing in confirming the diagnosis and guiding multidisciplinary management.
This reflexive thematic analysis of six interviews with men who have sex with men (MSM) reveals that while gonorrhoea is viewed as a manageable infection, awareness of antibiotic resistance is initially abstract but becomes a recognized future threat upon education, leading participants to support stewardship measures like regular testing and partner communication while viewing significant behavioral changes as unrealistic.