📄 Category

medicine

3079 papers

📄 medicine

Diminishing Protective Effects of EVAR on Postoperative Delirium Beyond Age 80: A Proposal for Tailored Prevention Strategies

While endovascular aneurysm repair (EVAR) significantly reduces the risk of postoperative delirium compared to open surgical repair in patients under 80 by mitigating surgical stress, this protective advantage diminishes in octogenarians due to overwhelming intrinsic vulnerability, necessitating aggressive geriatric co-management rather than relying solely on minimally invasive techniques.

Changsung Han, Chung Sung Woon, Miju Bae, Up Huh, Chang Won Kim, Gwon-Min Kim, Chung Won Lee2026-07-22
📄 medicine

Periodontitis and periodontal inflamed surface area in context of plant-based dietary patterns: Insights from the Hamburg City Health Study

In a large population-based study, higher adherence to healthful plant-based dietary patterns was significantly associated with reduced odds of severe periodontitis and lower periodontal inflamed surface area, while unhealthful plant-based patterns showed the opposite effect, with systemic inflammation partially mediating these relationships.

Merle Ebinghaus, Berit Lieske, Katrin Borof, Elina Petersen, Birgit-Christiane Zyriax, Ghazal Aarabi2026-07-22
📄 medicine

Sustained-release alphitolic acid-loaded hydrogel attenuates intervertebral disc degeneration through regulation of the MIF-SERPINE1-PI3K-Akt/NF-κB axis

This study identifies the MIF-SERPINE1-PI3K-Akt/NF-κB axis as a critical driver of intervertebral disc degeneration and demonstrates that an injectable, sustained-release hydrogel loaded with the MIF antagonist alphitolic acid effectively blocks this pathway to attenuate inflammation and restore extracellular matrix homeostasis in a rat model.

Ying Huai, Yanlong Kong, Qi Liang, Li Lin, Yonggang Qi, Xue Wang, Jingchuan Yan, Zhenshuo Zhang, Xiaoping Zhang, Qiudong (…)2026-07-22
📄 medicine

Characterizing the thrombotic spectrum and clinical phenotypes of tranexamic acid-associated adverse events: a pharmacovigilance study based on the FAERS database

This pharmacovigilance study utilizing the FAERS database characterizes the heterogeneous clinical phenotypes of tranexamic acid-associated thrombotic events, revealing that venous thromboembolism is the most frequent and severe type while cerebrovascular thrombosis disproportionately affects young females, thereby highlighting the need for enhanced risk stratification in specific high-risk populations.

Yayuan Zou, Shuo Wang, Youping Yuan, Ye Cao, Jia Liu, Zhonghua Guan2026-07-22
📄 medicine

Non-febrile headache burden among secondary school students in Bukavu, Democratic Republic of Congo: prevalence, clinical phenotype, and sex differences

This 2019 cross-sectional study of 400 secondary school students in Bukavu, DRC, reveals a high 6-month prevalence of non-febrile headaches (67.5%), predominantly migraines, which significantly impact academic performance and show marked sex differences with females experiencing more frequent and severe symptoms, highlighting a critical unmet need for screening and preventive care in this low-resource setting.

KASAMBI Julien BAYANDA, Célestin KAPUTU KALALA-MALU2026-07-22
📄 medicine

Community participation and belonging during rural nursing placements in Queensland: A cross-sectional study

This cross-sectional study of 153 undergraduate nursing students in rural Queensland found that while community interaction increased during placements, a sense of belonging was more strongly associated with the breadth of active community participation and repeated rural experiences than with mere exposure or interaction frequency.

Jessica Elliott, Liz Ryan, Professor Leah East, Professor Daniel Terry2026-07-22
📄 medicine

Prior Cervical Cancer Screening, Social Determinants of Health, and HIV Status Among Patients at the Cancer Disease Hospital, Zambia

This prospective study of 464 cervical cancer patients in Zambia found that prior screening was significantly associated with younger age, higher socioeconomic status (lower SDOH scores), and HIV-positive status, highlighting the critical role of social determinants and HIV care integration in screening uptake.

Graciela M. Nogueras Gonzalez, Susan Msadabwe, Bernadette Njala, Dyness Sakala, Mwando Chitula, Jane R. Montealegre, Sus (…)2026-07-22
📄 medicine

Development of emulsified systems containing S-(-)-Limonene and evaluation of the antibacterial effect against Klebsiella pneumoniae strains

This study demonstrates that S-(-)-limonene incorporated into stable nanoemulsions and nanoemulgels exhibits significant antibacterial activity against *Klebsiella pneumoniae*, supporting its potential as a candidate for treating skin wound infections.

Ravenna Leite da Silva, Andrea Fernanda Ramos de Paula, Maria Heloísa Furtunato Rocha, Hilzeth de Luna Freire Pessoa, El (…)2026-07-22
📄 medicine

Development of an In Vitro Denture Stomatitis Model Simulating Candida albicans Biofilm Formation and Detachment Under Daily Antiseptic Immersion

This study developed a reproducible in vitro model using standardized acrylic resin to demonstrate that daily immersion in 0.5% sodium hypochlorite or 0.12% chlorhexidine gluconate significantly reduces *Candida albicans* biofilm loads compared to water controls, providing a validated framework for evaluating denture-cleansing agents prior to clinical application.

Pornpot Jiangkongkho, Thatawee Khemwong2026-07-22
📄 medicine

Measles Vaccination Coverage, Caregiver Perceptions, and Information Sources in Five Selected Outbreak Districts of Zambia: A Descriptive Cross-Sectional Study

This cross-sectional study of 491 children in five Zambian districts reveals that while vaccination coverage appears adequate among those with records and health workers are the primary information source, the widespread lack of vaccination documentation and reliance on recall highlight critical gaps in monitoring and the need for strengthened record-keeping systems to improve measles outbreak preparedness.

Priscilla Nkonde Gardner, Dalitso Ngulube, Musole Chipoya, Kelvin Mwangilwa, Walter Azibadighi, Precious Kalubula, Lilli (…)2026-07-22