13396 papers
This international Technical Expert Panel study developed a clinical framework comprising five key domains—including specific symptoms, risk factors, and imaging guidelines—to identify suspected early hip osteoarthritis at the earliest radiographic stage, while emphasizing the need for future prospective validation before clinical implementation.
This cross-sectional study of 120 Japanese patients with gastrointestinal cancer undergoing outpatient chemotherapy found that higher Glasgow Prognostic Scores, indicating systemic inflammation and nutritional deterioration, are significantly associated with patient-reported symptoms affecting eating, particularly anorexia, taste changes, and diarrhea, with these associations being especially pronounced in patients aged 65 and older.
This cross-sectional study of 494 family caregivers in an outpatient oncology setting in Türkiye reveals that cumulative chemotherapy exposure and social isolation are the strongest independent correlates of increased caregiver burden and anxiety, supporting the need for routine distress screening during active cancer treatment.
This exploratory case-control study in Akwa Ibom State, Nigeria, suggests that dietary patterns rich in spices and seafood are inversely associated with breast cancer, while a pattern high in noodles, snacks, bread, and soda shows a positive association, though these findings are limited by methodological constraints and require further validation.
This study establishes preliminary gestational age-specific reference data for fetal thyroid size and signal intensity ratios on MRI in fetuses without known thyroid disease, while noting that wide interreader variability and a lack of diagnostic validation currently limit the clinical application of these metrics for individual cases.
This Turkish Oncology Group real-world study confirms that neoadjuvant nivolumab plus chemotherapy yields pathological response rates comparable to the CheckMate 816 trial in resectable non-small cell lung cancer, though over one-third of patients ultimately did not undergo surgery due to factors like T4 tumor status.
This retrospective proof-of-concept study demonstrates that radiomic features derived from [18F]FDG PET/CT, particularly when integrated into machine learning models, show potential prognostic value for predicting 5-year survival in patients with adrenocortical carcinoma, outperforming CT-based models despite the need for larger validation studies.
This multicenter study developed and externally validated an interpretable prenatal ultrasound model using nine predictors that accurately forecasts reduced postnatal split renal function in fetuses with ureteropelvic junction obstruction, demonstrating strong discrimination and potential utility for individualized counseling.
This retrospective study demonstrates that the perioperative Prognostic Nutritional Index (PNI) is a robust predictor of survival in curatively resected colorectal cancer, with survival-oriented machine-learning models offering enhanced multivariable risk discrimination compared to conventional statistical analyses.
This quasi-experimental study demonstrates that a brief, structured educational intervention significantly improved breast cancer knowledge and attitudes among undergraduate medical students in Pakistan, highlighting the need to integrate formal breast oncology and screening guidelines into the undergraduate curriculum.