3708 papers
This study clarifies that the endopelvic fascia is not an isolated membrane but a continuous connective tissue system linking the obturator fascia to the rectal wall and hiatal ligament, providing a crucial anatomical basis for defining surgical dissection planes in rectal cancer surgery.
This comparative neuropsychological study of Indian patients reveals that Progressive Supranuclear Palsy (PSP) exhibits significantly greater global and domain-specific cognitive impairment than Multiple System Atrophy (MSA), with PSP cognition closely linked to motor and mood severity while MSA cognition appears more driven by cognitive reserve.
This prospective study utilized microwave digestion and ICP-MS to analyze trace element and heavy metal profiles in gastrointestinal tumor versus healthy tissues, revealing significant associations between specific elemental alterations (particularly Cd, Pb, Fe, and Zn) and clinicopathological factors such as neoadjuvant therapy and lymphovascular invasion, thereby suggesting their potential as onco-biomarkers for personalized oncology.
This study demonstrates that moderate-to-late preterm birth independently increases the risk of severe lower respiratory tract infections across childhood and exhibits a significant synergistic interaction with respiratory syncytial virus (RSV) that amplifies disease severity, despite not altering susceptibility to pathogen acquisition.
This study demonstrates that inhaled pemetrexed-modified pulmonary surfactant nanoparticles loaded with paclitaxel (PEM-PSNP@PTX) effectively treat lung cancer by leveraging folate receptor-mediated dual targeting of tumor cells and macrophages to suppress tumor growth and reprogram the immunosuppressive microenvironment while minimizing systemic toxicity.
This study demonstrates that [68Ga]Ga-PentixaFor PET/CT frequently exhibits procedure-related uptake at surgical or interventional sites regardless of the time elapsed since the intervention or the anatomical location, highlighting a significant pitfall that correlates with [18F]FDG accumulation and may lead to false-positive interpretations.
This meta-research study demonstrates that systematic reviews of exercise interventions suffer from significant information loss compared to their source randomized controlled trials, primarily due to incomplete original reporting and further attrition during the synthesis process, particularly regarding equipment, adherence, provider characteristics, and tailoring methods.
This single-center quality improvement study demonstrates that a structured, physician-led educational intervention significantly enhances transition readiness, disease knowledge, self-management skills, and reproductive health awareness among adolescents with congenital heart disease.
This conceptual analysis argues that while existing biomedical appraisal tools effectively evaluate the technical soundness of study results, they fail to routinely verify whether the broader interpretations drawn from those results are actually supported by the specific comparisons the studies made, creating a critical gap between a result's validity and its application.
This study utilizing NHANES 2011–2018 data reveals that physically active US adults with prediabetes exhibit more diverse and strongly clustered cardiometabolic comorbidity patterns compared to their inactive counterparts, suggesting that physical activity fundamentally reshapes disease architecture rather than merely reducing prevalence.