📄 Category

medicine

13805 papers

📄 medicine

Functional Agent-Driven Computational Anatomy for Preoperative Siewert Classification of Adenocarcinoma of the Esophagogastric Junction Using Three-Dimensional Contrast- Enhanced CT: a retrospective multicenter diagnostic accuracy study

This retrospective multicenter study demonstrates that FACET, a functional agent-driven computational anatomy framework, improves the reproducibility and accuracy of preoperative Siewert classification for esophagogastric junction adenocarcinoma by converting subjective imaging assessments into calibrated, traceable 3D distance measurements on contrast-enhanced CT.

Yiting Liu, Zifan Chen, Ruojin Li, Shuangxi Li, Li Zhang, Xiaoting Li, Yinkui Wang, Kan Xue, Fei Shan, Lei Tang, Ziyu Li2026-10-14
📄 medicine

Spatial and Socio-Demographic Factors Associated with Stunting Among Under-Five Children in Bangladesh: Evidence from the Bangladesh Demographic and Health Surveys, 2011–2022

This study analyzes data from four Bangladesh Demographic and Health Surveys (2011–2022) to reveal a significant national decline in under-five stunting prevalence while highlighting persistent socioeconomic and spatial disparities, particularly among poorer, less educated, rural, and specific regional populations like Sylhet and Mymensingh.

Rasedul Islam, Prayas Sur Antu, Farjana Afrin Koasha, Md. Hazrat Ali, Faijun Nahar Mim2026-10-14
📄 medicine

Efficacy of Empagliflozin in Patients with Mild-to-Moderate Ulcerative Colitis: A Randomized Controlled Pilot Study.

This randomized, double-blind, placebo-controlled pilot study demonstrates that adjunctive empagliflozin therapy significantly improves clinical remission, quality of life, and inflammatory biomarkers in patients with mild-to-moderate ulcerative colitis, likely through the activation of the AMPK pathway.

Youmna Eldeeb, Sahar Elhaggar, Sahar hegazy, Mohamed Sarhan2026-10-14
📄 medicine

Tissue hypoperfusion after endovascular thrombectomy and functional outcome across heterogeneous imaging definitions: a systematic review and meta-analysis

This systematic review and meta-analysis demonstrates that persistent tissue hypoperfusion following successful endovascular thrombectomy is consistently associated with poor functional outcomes across diverse imaging definitions, highlighting its robust prognostic value despite methodological heterogeneity.

Fei Xu, Lu Cong, Dong Wang, Yuting Gao, Mengyuan Qiu, Zunjing Liu2026-10-14
📄 medicine

New nasal methicillin-resistant Staphylococcus aureus colonization during hospitalization in children: a prospective observational study from Iran

This prospective observational study from Iran found that 6.1% of hospitalized children acquired new nasal MRSA colonization, a risk significantly associated with female sex, underlying diseases, sulfonamide and corticosteroid exposure, and specific clinical units, though the findings are limited by a small sample size and require further validation.

Shahnaz Armin, Shadi Alimehr, Leila Azimi, Hannan Khodaei, Yasna Soleimani2026-10-14
📄 medicine

System-Level Delays For Anticoagulation Reversal  In Intracerebral Hemorrhage: Implications For Quality Improvement

This retrospective study identifies that implementing Code Stroke activation for all suspected intracerebral hemorrhage cases and adopting a time-critical algorithm featuring immediate, fixed-dose 4F-PCC reversal without waiting for INR results significantly reduces system-level delays and optimizes the acute management of anticoagulation-associated ICH.

Heidi Tan, Michael Carrillo, Diana Dench, Jefferson Chen, Mohammad Shafie, Wengui Yu2026-10-14
📄 medicine

A Rare Combined Hematoma of the Retzius Space and Broad Ligament Complicating Short Second-Stage Labor: A Case Report

This case report describes a rare instance of a life-threatening combined Retzius space and broad ligament hematoma following a short second-stage labor, highlighting the critical need for early surgical intervention when non-specific urinary symptoms and hemodynamic instability occur in the absence of external vaginal bleeding.

Yuan Lu, Lei Li, Xiaojing Zhang, Yuanyuan Zhang, Yunxia Wang2026-10-14
📄 medicine

Associations between novel anthropometric variables and short-term outcomes after acute type A aortic dissection repair

This retrospective study of 794 acute type A aortic dissection patients reveals that novel anthropometric variables, particularly Relative Fat Mass (RFM), are independently associated with postoperative acute kidney injury through inflammatory mediation and synergistic effects with cardiopulmonary bypass duration, while central obesity indicators including RFM, waist circumference, waist-to-height ratio, and body roundness index demonstrate U-shaped associations with short-term mortality.

Chao Deng, Wenyao Zhan, Hao Tang, Kangjun Shen, Jingyu Li, Zhenxiong Li, Song Tian, Ling Tan2026-10-14
📄 medicine

Connecting research and health systems for place-based transformation: the development of the NIHR Applied Research Collaboration Wessex infrastructure

This paper presents a prospective design account of the NIHR Applied Research Collaboration Wessex, detailing how its multi-network architecture and shared capabilities were developed to foster continuous reciprocal learning and align research with place-based health system challenges.

Michael Boniface, Cathy Bowen, Nisreen A. Alwan, Katherine Baker, Sam Chamberlain, Lindsey Cherry, Samuele Cortese, Sall (…)2026-10-14