📄 medicine

Use of large language models in German general practice: A cross-sectional survey

A 2026 cross-sectional survey of German general practitioners reveals that while approximately 80% already utilize large language models primarily for knowledge and decision support, widespread adoption is hindered by concerns over data accuracy, legal liability, and a lack of training, underscoring the urgent need for secure applications, clear regulations, and targeted education to facilitate their safe integration into primary care.

Hannah Maria Ott, Stefan Bösner2026-10-14✓ Author reviewed ⓘ
📄 medicine

Age- and Stage-Specific Transitions Between Colorectal Cancer- Specific and Other-Cause Mortality After Resection

This study of over 175,000 colorectal cancer patients reveals that the balance between cancer-specific and other-cause mortality after resection is dynamically determined by age, tumor stage, and survival time, with non-cancer deaths becoming predominant early in stage I and later in stage II for older patients, thereby underscoring the need for individualized prognostic planning.

Wenqiang Li, Guoshuai Xu, Wei Sun, Mingyu Zheng, Fangxu Yin, Bingbing Ren, Wenyue Ma, Xiaohui Dou, Yaqian Ping, Nan Yao (…)2026-10-14
📄 medicine

Sugar-sweetened beverage consumption of children and young people attending dental settings: A Mixed Methods Study

This mixed-methods study of children and young people in dental settings reveals that despite high awareness of the health risks, sugar-sweetened beverage consumption remains prevalent due to social and environmental factors, suggesting that future interventions should move beyond simple education to address these underlying determinants while leveraging the trusted role of dental professionals.

Samantha Watt, Jennifer Li, Catherine Brierley, Zoe Marshman2026-10-14
📄 medicine

First-year functional recovery after pancreaticoduodenectomy with pancreaticogastrostomy: prospective PGAQoL study of quality of life, exocrine function and nutritional status

This prospective study demonstrates that while quality of life significantly recovers within one year following pancreaticoduodenectomy with pancreaticogastrostomy, exocrine insufficiency and nutritional deficits remain highly prevalent, highlighting the critical need for ongoing symptom management and nutritional surveillance.

SERENA LANGELLA, PAOLA SALACONE, TERESA GALLO, ELISA SPERTI, NADIA RUSSOLILLO, MARTINA GUERRA, LORENZO EPIS, JONADA SULC (…)2026-10-14
📄 medicine

Are Large Multimodal Models Ready for Post-Thrombectomy mTICI Assessment? A Comparison with Physicians

While large multimodal models can achieve physician-level agreement in post-thrombectomy mTICI grading when provided with procedural reports, their performance relies heavily on text input and collapses significantly when assessing images alone, indicating that expert human interpretation remains essential for direct image-based reperfusion evaluation.

Michael Knott, Gerardo Napodano, Ekaterina Noeva, Liang Zhang, Moritz Brandenstein, Johannes Dinkel, Lili-Laura Bruta, J (…)2026-10-14
📄 medicine

Dynamic prognostic evaluation of oral squamous cell carcinoma using net and conditional survival rates: A retrospective cohort study

This retrospective cohort study of 783 oral squamous cell carcinoma patients demonstrates that incorporating net and conditional survival rates offers a more dynamic and clinically meaningful prognostic evaluation than overall survival alone, particularly by accounting for non-cancer mortality in older patients and revealing improving survival probabilities over time for long-term survivors.

Kosuke Shinohara, Masatoshi Hirayama, Kenyu Hashimoto, Ryoji Yoshidai, Kenta Kawahara, Tatsuro Yamamoto, Hikaru Nakashim (…)2026-10-14
📄 medicine

Six-Month Outcomes of Suture-Anchor Versus Hook-Plate Fixation for Rockwood Type III and V Acromioclavicular Joint Dislocation

This single-center observational study of 44 patients found no statistically significant differences in 6-month clinical and functional outcomes between suture-anchor and hook-plate fixation for Rockwood type III and V acromioclavicular joint dislocations, although the suture-anchor group showed a numerically faster return to daily activity at the cost of two fixation failures.

Sina Kamrani Moghadam, Mojtaba abbasalizadeh, Mohammad Amouzadeh-Lichahi, Ehsan Kazemnezhad Leyli, Samman Mohammadi, Kam (…)2026-10-14
📄 medicine

IDDA-Scored Abatacept-to-HSCT Course in Pediatric LRBA Deficiency

This paper demonstrates that the Immune Deficiency and Dysregulation Activity (IDDA) score is a practical metric for quantifying disease activity in LRBA deficiency, highlighting a case where abatacept successfully bridged a pediatric patient to curative HSCT and suggesting a potential survival benefit for abatacept-bridged patients in a retrospective cohort analysis.

Bin Hu, Zhaoling Wang, Yan Zhang, Liping Teng, Meiping Lu2026-10-14
📄 medicine

Impact of Formalin Fixation on Colonic Polyp Size and Post-Polypectomy Surveillance Thresholds: Evidence from a Prospective Paired Analysis

This prospective paired analysis demonstrates that formalin fixation causes a significant, directional reduction in colonic polyp size—particularly for small and sessile lesions—often shifting them across critical surveillance thresholds, thereby supporting the adoption of fresh ex-vivo measurements to ensure accurate post-polypectomy risk stratification.

Sabri Alper Karataş, Gökhan Varlı, Ahmet Aslan, Mehmet Biçer, Pırıl Akıncıoğlu2026-10-14
📄 medicine

Utility of intravoxel incoherent motion diffusion-weighted imaging in predicting pathological response to neoadjuvant immuno-chemotherapy for locally advanced gastric cancer

This prospective study demonstrates that intravoxel incoherent motion (IVIM) diffusion-weighted imaging, particularly when combining the apparent diffusion coefficient (ADC), true diffusion coefficient (D), and pseudodiffusion fraction (f), is a feasible and effective tool for early prediction of pathological response and prognosis in locally advanced gastric cancer patients undergoing neoadjuvant immuno-chemotherapy.

Qi Yao, Chenglong Luo, Xiao-xiao Lin, Di-xin Yao, Yi Wang, Shu-ning Xu, Jing Li2026-10-14