📄 medicine

Contralateral metachronous recurrence of ovarian mature teratoma following surgery in a child: a case report and literature review

This case report and literature review highlight the clinical significance of contralateral metachronous recurrence of ovarian mature teratoma in children, emphasizing the necessity of rigorous long-term ultrasound surveillance and individualized follow-up protocols to enable early detection and fertility-sparing intervention.

Jia Yin, Qiang Chen, Ping Yang2026-10-14
📄 medicine

Baroreflex sensitivity as a target for nonpharmacological interventions in elderly patients with supine hypertension and orthostatic hypotension

This retrospective study of 273 elderly patients demonstrates that specific autonomic deficits associated with supine hypertension and orthostatic hypotension involve distinct baroreflex and heart rate variability impairments that are potentially addressable through nonpharmacological heart rate variability biofeedback.

José R. Criado, Richard N. Gevirtz, Mary A. Kalafut2026-10-14
📄 medicine

From trials to practice: contralesional 1 Hz rTMS in chronic stroke - a first real-world retrospective cohort of 112 patients treated in routine outpatient care

This retrospective study of 112 chronic stroke patients demonstrates that routine outpatient contralesional 1 Hz rTMS combined with conventional therapy significantly reduces spasticity and yields modest motor improvements correlated with baseline severity, while showing no association with time since stroke, thereby supporting the treatment's real-world efficacy and challenging its exclusion based on chronicity.

Anne Lieb, Claudia Resch, Cristina Kohlmann Dell’Acqua, Peter Martus, Dania Humaidan, Andreas Jooß, Leidy Reyes Jimenez (…)2026-10-14
📄 medicine

County-level heterogeneity in the associations between meteorological factors and varicella incidence in Guangxi, China: a multicounty time-series study

This multicounty time-series study in Guangxi, China, reveals that meteorological factors exhibit distinct nonlinear, lagged, and geographically heterogeneous associations with varicella incidence, underscoring the need for tailored local risk assessment and surveillance strategies.

Zhang Linlin, Dong Aihu, Hua Yimeng, Lu Manyuan, Liao Qinfeng, Pan Guanxi, Zhang Zhiyong, Lu Huaxiang, QIN Jian2026-10-14
📄 medicine

Surgical treatment of tailgut cysts: a single-center analysis of 19 cases

This single-center retrospective study of 19 patients demonstrates that the posterior (Kraske) approach is a safe and effective surgical treatment for tailgut cysts, offering minimal complications and high satisfaction, while highlighting that multilobular morphology is a key risk factor for recurrence and diagnostic challenges.

Petro Zgurskyi, Nina Schraps, Baris Mercanoglu, Ramez Wahib, Jakob R. Izbicki, Thilo Hackert, Nathaniel Melling2026-10-14
📄 medicine

Sexual Function, Gender Congruence, and Well-Being Before Vaginoplasty: A Mixed-Methods Pilot Study of Trans Women on Gender-Affirming Hormone Therapy

This mixed-methods pilot study of pre-vaginoplasty trans women on hormone therapy reveals that while general well-being strongly predicts depressive symptoms, a specific narrative congruence regarding intimacy is more closely linked to sexual function and the desire for surgery, supporting a dual-pathway model for pre-operative counseling that distinguishes between mood management and surgical motivation.

Jan Ben Schulze, Murielle Plambeck, Marina Staindl, Roland von Känel, Sebastian Euler2026-10-14
📄 medicine

Structural implementation profiles of Antimicrobial Stewardship programmes in German hospitals: Evidence from an explorative cluster-analysis

A 2024 nationwide survey of German hospitals reveals that Antimicrobial Stewardship implementation profiles are primarily driven by the availability of dedicated personnel and specialized expertise, creating a divide between resource-intensive activities and legally mandated measures, while hospital size—not university status—correlates with advanced program development.

Sophia-Helen Sass, Alina Zimmermann, Gesche Först, Winfried V. Kern, Katja de With2026-10-14
📄 medicine

APACHE II Score as a Predictor of Outcomes in Patients with Perforation Peritonitis: A Prospective Observational Study

This prospective observational study of 66 patients in India demonstrates that the admission APACHE II score is a significant predictor of in-hospital mortality in perforation peritonitis, showing high specificity (95.9%) at a cut-off of ≥20, which makes it a useful bedside tool for risk stratification and prioritizing critical care, despite its modest sensitivity.

Neha Srinivas, Mukund Mangarai2026-10-14
📄 medicine

Three-dimensional fractal analysis of region-specific trabecular changes six months after Le Fort I osteotomy using cone-beam computed tomography

This retrospective study utilizing cone-beam computed tomography and three-dimensional fractal analysis reveals that while the radiographic trabecular pattern at Le Fort I osteotomy sites shows a significant decrease in fractal dimension six months post-surgery, the magnitude of this change remains consistent across different anatomical sites, regions, and sides, suggesting that fractal dimension serves as a complementary imaging metric rather than a direct indicator of bone healing.

Hilal Algül¹, Mahzun Yıldız², Anıl Kamal², Emre Karahan³, Mehmet Emre Yurttutan², Ayşe Tuba Altuğ¹2026-10-14