📄 medicine

Primary caregivers’ perspectives on metaverse-based care training for home-based stroke care: a qualitative study

This qualitative study of twelve Shanghai-based caregivers reveals that while they recognize the potential of immersive metaverse training to address critical gaps in stroke care knowledge and emergency response, its widespread adoption is currently hindered by practical concerns regarding device tolerance, economic costs, and the transferability of virtual skills to real-world scenarios.

Haonan Qin, Jiale Xu, Yijia Li, Xuan Zhou, lanshu Zhou, Qiuyi Wang2026-10-14
📄 medicine

Responsiveness to Erythropoiesis‑Stimulating Agents and Hemoglobin Variability in Japanese Patients With End‑Stage Kidney Disease

This retrospective study of Japanese patients with end-stage kidney disease demonstrates that a higher erythropoietin resistance index (ERI) is independently associated with greater hemoglobin variability, suggesting ERI could serve as a useful surrogate marker for predicting hemoglobin fluctuations.

Toshihide Hayashi, Tatsunori Noto, Minako Harada, Yasunori Takahashi, Yoshihiko Imamura2026-10-14
📄 medicine

Knowledge, Attitudes and Practices Towards Onchocerciasis among Children and Adolescents in the Formerly Endemic Foci of Mexico: A Cross-Sectional Survey in the Post-Verification Period

A cross-sectional survey conducted in Mexico's formerly endemic regions of Oaxaca and Chiapas reveals that while children and adolescents hold favorable attitudes toward onchocerciasis control, their specific knowledge of the disease and its blackfly vector remains critically low, highlighting the urgent need for sustained health education to maintain elimination gains in the post-verification period.

Nadia A. Fernández-Santos, Oluwadamilare Ganiu Dauda, Alejandro Tovías-Rodríguez, Frank O. Richards, Gabriel L. Hamer, M (…)2026-10-14
📄 medicine

Interpretable Predictive Modeling for Early Sepsis in the Emergency Department: Development and Temporal External Validation

This study developed and temporally validated an interpretable XGBoost model using initial emergency department data that achieved high predictive accuracy (AUC 0.972) and exceptional specificity (98.26%) for early sepsis detection, while utilizing SHAP analysis to provide transparent, actionable insights for clinical decision-making.

Xuefei Lu, Xiaoyu Zhang, zhijie Cao, Lina Ma, Jing Ma, Siyi Wang, Li Zhang2026-10-14
📄 medicine

Serum Uric Acid Identifies a Kidney Filtration–Risk Phenotype in Diabetes-Enriched Non-Obese Metabolic Dysfunction-Associated Steatotic Liver Disease: A Multicentre Cohort Study

In a multicentre cohort study of non-obese individuals with metabolic dysfunction-associated steatotic liver disease (MASLD), predominantly those with type 2 diabetes, higher baseline serum uric acid levels were identified as a significant predictor of future kidney filtration decline, suggesting its utility for risk stratification and enhanced renal surveillance despite not establishing causality or treatment indications.

wenxuan li, jinghan zheng, wenshan lv, lili xu, ke si, yuzhao liu, shuhui hu, shengli wu, Yuancheng Dai, qijuan dong, qi (…)2026-10-14
📄 medicine

Correlation Between Demographic Data and Intraoperative Distal Femoral Anthropometry in Patients Undergoing Total Knee Arthroplasty

This study of 78 Nigerian patients undergoing primary total knee arthroplasty reveals that sex, height, and age are significant predictors of intraoperative distal femoral dimensions, suggesting these demographic factors can aid preoperative planning for femoral component sizing.

Lateef Olawale Oyebanji, kehinde Adesola Alatishe, Eval Gershom Igwe, Opeyemi Olusunmade, Aofolajuwonlo Taiwo2026-10-14
📄 medicine

Factors associated with health literacy among caregivers of patients with advanced cancer: a cross-sectional path analysis using structural equation modelling

This cross-sectional study of 280 family caregivers in China reveals that higher self-efficacy and lower caregiver burden are significantly associated with better health literacy among those caring for patients with advanced cancer, while health anxiety showed no significant link.

Qing Wu, Cen Pan, Xiaoying Zhu, Wei Wang, Hongyang Hu2026-10-14
📄 medicine

Comparative graft survival and visual outcomes of penetrating keratoplasty versus lamellar keratoplasty: A retrospective cohort study

This retrospective cohort study found that while lamellar keratoplasty initially demonstrated lower graft failure rates and better visual outcomes than penetrating keratoplasty, the difference in graft failure was not statistically significant after adjusting for surgical indications and case mix.

Omar Alhadlaq, Yaser Althnayan, Sulaiman Alsamaan, Abdullah Alharbi, Arwa Alkhuraiji2026-10-14
📄 medicine

Synchronous Medullary Carcinoma and Primary Follicular Lymphoma in the Same Thyroid Lobe: A Case Report and Literature Review

This case report describes the exceptionally rare synchronous occurrence of medullary thyroid carcinoma and primary follicular lymphoma (grade 3b) within a single thyroid lobe of a patient with autoimmune thyroiditis, emphasizing the necessity of comprehensive histological and immunohistochemical evaluation for accurate diagnosis and management.

Nano Pachuashvili, Andrey Varlamov, Elizaveta Churilova, Dmitry Abramov, Dmitry Konovalov, Liliya Urusova2026-10-14