📄 medicine

How leadership support nurses in continuous professional development in municipal in-patient acute care: A qualitative study

This qualitative study of municipal in-patient acute care services in Norway reveals that effective leadership, characterized by organizational strategies, relationship-oriented management, and collaborative interprofessional practices, is pivotal in fostering a culture that supports nurses' continuous professional development and competence growth.

Torunn Kitty Vatnøy, Marianne Trygg Solberg2026-10-14
📄 medicine

Challenges and Adaptation after a Fall: A Mixed Methods Study of Community-Dwelling Older Adults Discharged Home from the Emergency Department

This mixed methods study reveals that many community-dwelling older adults experience persistent physical and psychological declines one month after a fall-related emergency department discharge, while highlighting the critical role of social support in pain management and the diverse adaptive strategies patients employ during early recovery.

Michelle Lin, David Kim, Caitlin Toth¹, Maria Pacella-LaBarbara, Brian Suffoletto2026-10-14
📄 medicine

Early lower expression of PD-L1 on M1 monocyte is a associated with prevalent septic shock in older adult sepsis: an observational cohort study

In an observational cohort study of older adults with sepsis, lower early expression of PD-L1 on M1 monocytes within the first 24 hours was independently associated with the presence of septic shock and demonstrated improved diagnostic accuracy when combined with the SOFA score.

Qian Gao, Beibei Liu, Li Yang, Shubin Guo, Tiecheng Yang2026-10-14
📄 medicine

A pragmatic randomized controlled trial of physician’s-choice systemic anticancer therapy versus best supportive care in patients with end-stage advanced solid tumors: the TRUE trial protocol

The TRUE trial is an ongoing pragmatic randomized controlled trial comparing physician's-choice systemic anticancer therapy against best supportive care in patients with end-stage advanced solid tumors to determine whether additional treatment improves overall survival and quality of life or if prioritizing supportive care is more beneficial.

Tomonori Mizutani, Tsuguo Iwatani, Takuya Kawahara, Makoto Ueno, Shiho Kuji, Takako Kuroda, Atsuo Takashima, Ryosuke Tat (…)2026-10-14
📄 medicine

Willingness to use and pay for a virtual urgent care service among emergency department patients in Singapore: a cross-sectional study

This cross-sectional study of 168 Singaporean emergency department patients and caregivers reveals that willingness to use and pay for virtual urgent care services increases with perceived clinical urgency, with acceptance driven by scenario-specific values such as convenience for mild conditions and timely escalation for severe ones, alongside factors like trust and digital confidence.

Kris Chua, Shi Yun Low, Jason Lee, Serene Wong, Stephanie Q Ko, Ivo Vlaev2026-10-14
📄 medicine

Partial Mediation by Self-Efficacy of the Association Between Information-Motivation-Behavioral Skills Nursing and Quality of Life After Lung Cancer Cryoablation: A Retrospective Cohort Study With Propensity Score Matching

This retrospective cohort study with propensity score matching demonstrates that self-efficacy serves as a statistically significant but fragile partial mediator, accounting for approximately 12% of the positive association between Information-Motivation-Behavioral Skills nursing interventions and improved quality of life in lung cancer patients undergoing cryoablation.

Huanzhi Peng, Zhuoxin Dai, Lili Tang, Junwei Wang, Miao Yang, Mingxi HU, Mengyang Chang, Quanxing Liu2026-10-14
📄 medicine

Impact of Cardiorenal syndrome Type 1 on Mortality and Health-related Quality of Life among Patients Admitted for Acute Heart Failure in a Nigeria Tertiary Hospital: A Prospective Cohort Analysis

This prospective cohort study conducted at a Nigerian tertiary hospital reveals that cardiorenal syndrome type 1 affects nearly half of acute heart failure patients and is significantly associated with prolonged hospitalization, higher mortality rates, and reduced health-related quality of life at 30 days.

Rilwan Adegboyega Oyekunle, Yekeen Ayodele Ayoola, Maryam Nike Abdul-Raheem, Adamu Adamu, Ismail Olayemi Ayanbisi, Remig (…)2026-10-14
📄 medicine

Mesenteric Adhesion and Poorer Perioperative Outcomes in Gastric Submucosal Tumors: A Retrospective Study of Endoscopic Full-Thickness Resection

This retrospective study of 202 patients demonstrates that mesenteric adhesion, driven by risk factors such as posterior wall location, large tumor size, and extraluminal growth, significantly prolongs operative time, increases inflammatory response, and raises hospitalization costs in gastric submucosal tumors treated with endoscopic full-thickness resection, thereby highlighting the need for careful preoperative assessment and caution in such cases.

Qin Zeng, Ziqi Sui, Yuxuan Chen, Liwen Feng, Mi Zhou, Xinli Chen, Shuo Zhang2026-10-14
📄 medicine

Nurse-led non-ICU early rehabilitation after liver transplantation: a quasi-experimental study

This quasi-experimental study demonstrates that a nurse-led non-ICU early rehabilitation pathway for liver transplant recipients is associated with accelerated recovery milestones, reduced invasive device retention, and shorter hospital stays compared to conventional ICU-transition care, though findings are limited by the historical control design.

Jing Xu, Xiaofeng Xu, Ting Zeng, Gang Xu, Jiayin Yang2026-10-14
📄 medicine

Flipped classroom combined with problem-based learning in peri-operative anaphylaxis training for nurse anesthetists: a randomized controlled trial

This randomized controlled trial demonstrates that an integrated flipped classroom and problem-based learning (FC-PBL) teaching model significantly enhances team emergency performance, theoretical knowledge, practical skills, and self-confidence among nurse anesthetists training for peri-operative anaphylaxis compared to traditional lectures.

Yan-Ling Ren, Hao-Yong Zhang, Ming-Zhu Jing, Jia-Qi Chen, Wei Zhang, Fei Xing2026-10-14