13805 papers
This study demonstrates that a refined multi-parameter model integrating cerebrospinal fluid IL-6 and IL-17 cytokine levels with routine biochemical indexes significantly improves the early differentiation between bacterial and viral meningitis in children, achieving high diagnostic accuracy and strong predictive value.
This study demonstrates that longitudinal edited proton magnetic resonance spectroscopy is a feasible translational tool for monitoring dynamic neurochemical changes in experimental stroke, revealing a transient reduction in peri-lesional GABA that recovers by 30 days despite minimal behavioral impairment and absent persistent cortical inflammation.
This cross-sectional study at a rural faith-based hospital in Northern Rwanda found that 13.2% of women reported a history of induced abortion, with younger age, having multiple sexual partners, and being a primigravida identified as significant independent risk factors.
This multicentre observational study of the 2024–2025 Réunion Island outbreak reveals that severe chikungunya infection requiring ICU admission predominantly affects older patients with comorbidities, carries a 29% in-hospital mortality rate driven primarily by pre-existing diabetes, and is characterized by frequent multiorgan failure, particularly hepatorenal involvement.
This study demonstrates that local excision after neoadjuvant chemoradiotherapy offers favorable oncological outcomes and high organ preservation rates for carefully selected patients with locally advanced rectal cancer who achieved a clinical complete or near-complete response, even among those initially scheduled for abdominoperineal resection, though it is associated with substantial complication and local recurrence rates.
This Q method study reveals that while Belgian nephrologists generally reject explicit paternalism, their shared decision-making practices regarding dialysis modality selection are shaped by three distinct conceptual models and often constrained by unexamined organizational norms and case-by-case problem-solving that inadvertently limit patient access to home-based therapies.
This paired-knee MRI study reveals that following anterior cruciate ligament reconstruction, the lateral meniscus exhibits significantly greater posterior and lateral positional asymmetry compared to the contralateral knee during early flexion under axial loading, suggesting altered knee kinematics affect meniscal behavior.
This study demonstrates that novel atrioventricular and ventriculoarterial coupling indices derived from cardiac MRI and invasive hemodynamics outperform traditional metrics in predicting adverse outcomes for Hypoplastic Left Heart Syndrome patients with stage II palliation prior to Fontan completion.
This retrospective study demonstrates that preoperative nutritional and exercise interventions significantly reduce postoperative hospital stays and improve short-term outcomes for older frail patients undergoing hepatectomy for hepatocellular carcinoma, although long-term survival rates remained unchanged between the intervention and non-intervention groups.
This prospective study in eastern Nepal utilized metagenomic next-generation sequencing to identify Enterovirus C and Elizabethkingia meningoseptica, including co-infections, as significant etiologies of pediatric central nervous system infections that often remain undiagnosed by conventional methods.