📄 medicine

Covariate Adjustment and Interpretation of Mortality Estimates in ADHD: A Systematic Review and Meta-analysis

This systematic review and meta-analysis of 15 studies reveals that while ADHD is associated with elevated mortality, the evidence is of very low certainty due to high heterogeneity, substantial variation in covariate adjustment strategies, and wide prediction intervals that often cross the null, cautioning against interpreting pooled estimates as precise measures of risk across different settings.

Yu Chang, Ming-Hong Hsieh, Yi-Chun Liu2026-10-14
📄 medicine

Psychological, motivational, and physical effects of a supervised exercise program in women with breast cancer undergoing adjuvant treatment: a pilot intervention study

This pilot study demonstrates that a supervised, individualized exercise program for women with breast cancer undergoing adjuvant treatment significantly improves physical strength and functional capacity while reducing anxiety and depression, thereby enhancing overall quality of life and intrinsic motivation for exercise.

Santiago Fresno-Alba, Marta Leyton-Román, Ana Ferri Caruana, Ruth Jiménez-Castuera2026-10-14
📄 medicine

Modelling Malaria at the Human–Environment Interface in the Cross-Border Oiapoque Basin: A One Health ABM-GIS Approach

This study employs a One Health Agent-Based Model integrated with GIS to demonstrate that cross-border malaria in the Oiapoque basin is an emergent socio-ecological property driven by the pendular mobility of high-risk occupational groups into deep-forest ecotones, revealing that current static health interventions have reached spatial saturation and necessitating a strategic shift toward targeted, mobile interventions at high-risk exposure sites.

André Leite Rodrigues, Paulo Morgado, Patrícia Abrantes, André Alves, Ana Louro, Eduarda Marques da Costa2026-10-14
📄 medicine

Combined Effects of Physical Inactivity and Screen Time on Cardiorespiratory Fitness among Adolescents in Karachi: An Analytical Study

This analytical study of 276 adolescents in Karachi reveals that excessive screen time and physical inactivity are significantly associated with adverse changes in cardiorespiratory fitness parameters, including blood pressure, heart rate, and oxygen saturation.

Neha Fatima Patel, Sidra Habib, Tanzeela Ejaz, Asba Shouqat But, Asfara Tariq, Farooq Azam Rathore2026-10-14
📄 medicine

Early-onset adenocarcinoma of the ampullary rectum: a case report

This case report describes a rare instance of early-onset poorly differentiated adenocarcinoma of the ampullary rectum in a 33-year-old man, highlighting the importance of maintaining a high index of suspicion for colorectal malignancy in younger patients with persistent gastrointestinal symptoms to ensure timely diagnosis and appropriate surgical management.

Ziyali I. Rzayev, Fariz H. Jamalov, Dilara A. Akyuz, Mazahir M. Mursalov, Imran A. Shafiev, Azer Sh. Gasimov, Terane P. (…)2026-10-14
📄 medicine

Single-camera pose estimation for quantitative assessment of balance deficits: a proof-of-concept using graded acute alcohol intake

This proof-of-concept study demonstrates that a single-camera, markerless pose estimation system can detect graded balance deficits induced by acute alcohol intake with significantly higher sensitivity and accuracy than traditional clinical rating scales, which often fail to register impairment due to ceiling effects.

Nadine Domnik, Nerea Lopez, Tim Unger, Suno Diekmann, Alexander Andrea Tarnutzer, Olivier Lambercy2026-10-14
📄 medicine

Research priorities within LGBTQIA+ perinatal care: results of a priority setting partnership

Using the James Lind Alliance methodology, this study engaged LGBTQIA+ individuals and perinatal health professionals in the UK to collaboratively identify and prioritize the top 24 research uncertainties in LGBTQIA+ perinatal care, with the leading priority focusing on how healthcare responses to intersectional identities impact access to parenthood and quality of care.

Ilana Levene, Mari Greenfield, Catherine Meads, Eshe Kiama Zuri, Zoe Darwin, Ash Bainbridge, Jacob Stokoe, Dean J. Conno (…)2026-10-14
📄 medicine

I never knew that one day I would be called a doctor”: A participatory process evaluation of citizen scientists’ participation in behaviour change intervention regarding schistosomiasis among endemic communities of western Uganda

This participatory process evaluation of the ATRAP Uganda project demonstrates that citizen science-led behavior change interventions effectively empowered community members and improved schistosomiasis prevention practices in western Uganda, while highlighting the need for sustainable local ownership and integrated WASH support to address implementation challenges.

Maxson Kenneth Anyolitho, Karolien Poels, Caroline Masquillier, Viola Nilah Nyakato, Tine Huyse2026-10-14
📄 medicine

Predictive Value of Serum Total Calcium for Surgical Intervention in Neonatal Necrotizing Enterocolitis: A Single-Center Retrospective Case-Control Study

This single-center retrospective case-control study demonstrates that low serum total calcium measured within 24 hours of disease onset is an independent predictor of the need for surgical intervention in neonates with necrotizing enterocolitis, exhibiting superior predictive accuracy compared to inflammatory markers like CRP and PCT.

Zhixuan Yuan, Xuejie Zheng, Ming Chen, Yang Wang, Shenggang Ding2026-10-14