📄 medicine

Epidemiological Characteristics of Infectious Diseases Among Homeless Individuals With Mental Illness and Development of a Seamless Care Model in Southern China

This study investigates the epidemiology of infectious diseases among homeless individuals with mental illness in southern China, identifying a 21.23% prevalence rate driven largely by viral hepatitis and syphilis, and proposes a comprehensive seamless care model to address the unique healthcare needs of this vulnerable population.

Linli Feng, Xiaoling Cheng2026-07-14
📄 medicine

Robotic-Assisted versus Navigated and Freehand Posterior Lumbar Fusion: A Retrospective Propensity-Weighted Cohort Study with Elderly, Obese, and Multilevel Subgroup Analyses

This retrospective propensity-weighted cohort study demonstrates that robotic-assisted posterior lumbar fusion offers consistent perioperative advantages, including reduced operating time, blood loss, length of stay, and complications, across elderly, obese, multilevel, and general degenerative patient subgroups compared to navigated and freehand techniques, though these benefits may be partly attributed to the minimally invasive approach enabled by the technology.

Conor McNamee, Donal Shanley, Aubrie Sowa, Salman Keraidi, Hania Ibrahim, Jake M. McDonnell, Stacey Darwish, Joseph S. B (…)2026-07-14
📄 medicine

Comparison of Pharmacokinetic Properties of Mitomycin C-Based Regimens for Hyperthermic Intraperitoneal Chemotherapy in a Rat Model

This study in a rat model found that while three different Mitomycin-C HIPEC regimens yielded comparable peritoneal-to-plasma exposure ratios, the protocol using three divided doses resulted in significantly lower plasma concentrations than the single-bolus or two-dose approaches.

Sangho Joo, Kyung-Sun Moon, Seunghee Baek, Sung-Hoon Ahn, Eun Jung Park2026-07-14
📄 medicine

Clinical, cerebrospinal fluid, and microbiological characteristics of childhood purulent meningitis at a tertiary pediatric hospital in Vietnam: a retrospective study

This retrospective study of 102 children at a tertiary Vietnamese hospital reveals that purulent meningitis predominantly affects those under five years of age, frequently presents without classic meningeal signs, and is most commonly caused by *Streptococcus pneumoniae* despite a low overall microbiological confirmation rate.

Tung Cao Viet, Huong Le Thi Lan, Nam Dao Huu, Ly Pham Ha, Thuy Ha Minh, Khiem Nguyen Van2026-07-14
📄 medicine

From Adversity to Suicidality: Differential Effects of ACE Subtypes on Suicidal Thoughts and Behaviors among Adolescents in the United States

Using nationally representative 2023 YRBS data, this study reveals that while specific ACE subtypes like sexual abuse and emotional neglect significantly increase the risk of suicidal thoughts and behaviors among U.S. adolescents, these risks are compounded by persistent sadness and vary across racial and ethnic groups, highlighting the need for culturally responsive, trauma-informed interventions.

Philip Baiden, Batholomew Chireh, Sheriffa Mahama, Raymond Glikpo, Judith Anagbonu, Vera Mets, Helena Baffoe2026-07-14
📄 medicine

The Chain-Mediating Roles of Fear of Cancer Recurrence and Insight Between Self-Disgust and Rehabilitation Exercise Adherence in Patients with Malignant Bone Tumors

This cross-sectional study of 266 patients with malignant bone tumors reveals that self-disgust negatively impacts rehabilitation exercise adherence through both independent and sequential mediating pathways involving fear of cancer recurrence and insight, suggesting that integrated psychological and cognitive interventions could improve long-term rehabilitation outcomes.

Qin Yu, Xiaofeng Yin, Qiuru Wang, Ying He, Ye Li, Xiaoyan Liu2026-07-14
📄 medicine

A Cross-Sectional Survey of Workplace Violence Prevention Policies and Reporting Practices in Healthcare Settings

This cross-sectional survey reveals that despite the widespread existence of workplace violence prevention policies in healthcare settings, these measures are largely perceived as ineffective and fail to address the crisis of underreporting, prompting calls for enhanced security, stricter enforcement, and better administrative support.

Hanna Schindler, Austin Hanrahan, Nadiya Persaud, Tiffany Brown, Michelle Wallen2026-07-14
📄 medicine

The effects of food safety guidelines in comparison to the neutropenic diet on infection rates and nutritional status in patients with acute myeloid leukemia undergoing remission induction chemotherapy: a randomized clinical trial

This randomized clinical trial found that for adult patients with acute myeloid leukemia undergoing induction chemotherapy, following food safety guidelines resulted in similar infection rates and nutritional outcomes compared to the restrictive neutropenic diet, while offering a less burdensome and more adherent dietary approach.

Yasaman Hosseini, Sajjad Moradi, Faramarz Jalili, Shirley Hodder, Sahar Tavakkoli Shiraji, Seied Asadollah Mousavi, Hoss (…)2026-07-14
📄 medicine

Effect of comprehensive nursing intervention on quality of life in children with recurrent medulloblastoma undergoing chemoradiotherapy: a randomized controlled study

This randomized controlled study demonstrates that a comprehensive nursing intervention significantly improves quality of life and nursing quality scores in children with recurrent medulloblastoma undergoing chemoradiotherapy, while also highlighting the influence of socioeconomic factors and nursing resources on care outcomes.

Yongrong Dong, Jiehong Zheng, Yunkun Wang2026-07-14
📄 medicine

Reproducing comparative therapeutic efficacy in relapsed refractory multiple myeloma using an external control arm derived from historical clinical trial data

This study demonstrates that an external control arm constructed from harmonized historical clinical trial data using propensity-score matching can accurately reproduce the overall survival treatment effect observed in a randomized controlled trial for relapsed/refractory multiple myeloma, supporting the utility of such methods when high-quality patient-level data are available.

Xiang Yin, Mehmet Burcu, Mark D. Stewart, Elizabeth Stuart, Ruthanna Davi2026-07-14