📄 Category

medicine

4098 papers

📄 medicine

Magnitude and determinants of leprosy-related stigma among persons affected by leprosy and community contacts in southern Benin: a mixed-methods study

This mixed-methods study in southern Benin reveals a substantial burden of leprosy-related stigma among both affected individuals and community contacts, identifying active screening, late diagnosis, and rural residence as key determinants that necessitate targeted, culturally sensitive interventions to mitigate psychosocial consequences.

Fifamin Noël Christelle GBAGUIDI, Sètondji Diane ZANVO, Sonagnon Inès Elvire AGBO, Sèdjro Gimatal Esaï ANAGONOU, Karine (…)2026-07-14
📄 medicine

Geographic Differences and Their Influence on Tolvaptan Treatment in Patients with ADPKD

This multicenter retrospective study in Turkey demonstrates that geographic and climatic factors, particularly high temperatures and prolonged sunshine, significantly influence tolvaptan tolerability and biochemical responses in patients with ADPKD, suggesting that environmental parameters should be considered for individualized dose adjustments to improve safety and adherence.

Sibel Gokcay Bek, Ismail Kocyigit, Kadir Gökhan Atılgan, Emre Aydın, Sibel Balcı, Özgür Akın Oto, Dilek Gibyeli, Tolga Y (…)2026-07-14
📄 medicine

Horizontal Versus Vertical Scleral Tunnel Orientation in Flanged Intrascleral Fixation: A 2-Year Comparative Study

In a retrospective 2-year comparative study of 107 eyes, horizontal scleral tunnel orientation was associated with superior 2-year refractive predictability and reduced intraocular lens tilt compared to vertical orientation in flanged intrascleral fixation, though the non-randomized design limits these findings to hypothesis-generating conclusions.

Burhan Başkan, Yusuf Evcimen2026-07-14
📄 medicine

Workplace Interventions to Improve Physical Activity, Reduce Sedentary Behavior, and Promote Healthy Diet Among Employees in Low- and Middle- Income Countries: A Systematic Review

This systematic review of 16 studies across six low- and middle-income countries indicates that multi-component workplace interventions are the most effective strategy for improving cardiovascular risk profiles among employees, despite challenges such as high attrition rates and a moderate-to-high risk of bias in the existing literature.

Samina Akhtar, Khadija A. Sumra, Zainab Samad, Gerald S. Bloomfield, Salim S. Virani, Simon Walker, Gerardo Z. Gomez, Ay (…)2026-07-14
📄 medicine

Integrated Telemedicine and Psychological Counseling for Mental Health Outcomes in HCC Patients: A Multi-center Cohort Study

In a multi-center retrospective cohort study of 349 hepatocellular carcinoma patients in China, moderate participation in an integrated WeChat-based telemedicine and psychological counseling program was associated with statistically significant improvements in depression, quality of life, distress, and sleep at 12 months, although these gains generally fell short of established clinically meaningful thresholds and the observational design limits causal inference.

Feng Jiang, Xiaoqin Liang, Shuang Jin, Yan Li, Tianhong Cai, Haijun Tang2026-07-14
📄 medicine

Sociodemographic, Gender, and Regional Drivers of Comprehensive HIV and AIDS Knowledge and Testing Uptake among Indian Youth: Findings from Nationally Representative Survey

Using nationally representative NFHS-5 data, this study reveals that comprehensive HIV knowledge and testing uptake among Indian youth remain low and inequitable, with education, wealth, marital status, and geographic region identified as key determinants necessitating targeted, equity-focused interventions.

Joseph D. Williams, T. Ilanchezhian, V. Sampath Kumar, A. Vijayaraman, S. Chandrasekaran, P. Rajendra Prasad, R. Shanmug (…)2026-07-14
📄 medicine

Operative timing and patient-reported recovery in panfacial fractures: a retrospective cohort analysis of intermediate surgical delay at a government teaching hospital in northwestern India

This retrospective cohort study of 120 patients at a government teaching hospital in northwestern India demonstrates that panfacial fracture surgery delayed by 8–30 days due to bureaucratic procurement and scheduling barriers is independently associated with significantly inferior functional and aesthetic outcomes at 12 months compared to early intervention.

Chandrashekhar Chattopadhyay¹, Vikas Deo¹, Charu Chouhan¹, Mamta Patel¹, Priti Airun, Kamal Singh, Ayush Garg¹, Sugandha (…)2026-07-14
📄 medicine

Evaluating efficacy and safety of GVAX alone vs combinations in treatment of pancreatic adenocarcinoma; a single arm meta-analysis of Randomized Controlled trials

This single-arm meta-analysis of randomized controlled trials found no statistically significant improvement in overall survival or progression-free survival for patients with metastatic pancreatic adenocarcinoma treated with GVAX and CRS-207 vaccines, highlighting the need for larger, well-structured studies due to high heterogeneity and limited data.

Nabahat Shafi, Syeda Kashaf Batool, Arsalan Ahmed, Fatima Faisal, Hijab Furqan, Basant Ahmed Mahmoud, Hafiza Tooba Siddi (…)2026-07-14
📄 medicine

Quantification of Choroidal Blood Flow and Structure in High Myopia

This study utilized ultra-widefield SS-OCTA to demonstrate that high myopia induces marked spatiotemporal heterogeneity in choroidal remodeling, characterized by an early compensatory increase in choriocapillaris density followed by a significant, region-specific decline in vascular density and stromal volume alongside an increase in the choroidal stromal index.

Anqi Lei, Rui Li, Weiqun Hu, Zexu Wang, Chunmei Zou, Danna Zhang2026-07-14