📄 medicine

Factors Associated With Treatment Non-Completion Among Adolescents and Young People With Substance Use Disorders in Low- and Middle-Income Countries: A Systematic Review

This systematic review of five studies from Brazil, Mexico, and Türkiye reveals that while family involvement and school engagement may support treatment retention for adolescents with substance use disorders in low- and middle-income countries, the evidence base remains geographically limited, methodologically heterogeneous, and sparse regarding key regions like Sub-Saharan Africa and South Asia.

Olawale Folarin, Samuel Oluwadamilare Akinwande2026-10-14
📄 medicine

Olive and Avocado Oils Ameliorate Lipid Profiles and Hepatocellular Effect in High-Fat-Diet Rats: An In Vivo and In Silico Study

This study demonstrates that the combined administration of olive and avocado oils effectively ameliorates high-fat diet-induced hyperlipidemia and liver dysfunction in rats, a finding supported by molecular docking evidence showing strong binding of their bioactive compounds to HMG-CoA reductase.

Mohamed S. Nassr, Fatma M. Salem, Reem E. Fathi, Salma A. Rabie, Laila A. Mostafa, Naiera E. Mohamed, Samah M. Fathy, Za (…)2026-10-14
📄 medicine

Live ,the Liver Life: From equations to allocation: a wave-form prior for early planning of hepatitis C screening under NVHCP and the WHO 2030 strategy

This paper proposes a wave-form prior framework that leverages a latitudinal envelope to transport prevalence data from a known location to Varanasi, enabling early, cost-effective planning for Hepatitis C screening under India's NVHCP and WHO 2030 goals by quantifying the value of initial estimates while cautioning that such priors serve best as starting specifications rather than precise district-level maps.

Shrish Chandra Srivastava2026-10-14
📄 medicine

Epidemiological characteristics of six common respiratory pathogen infections in children in Tongren, China

This retrospective study of 11,910 pediatric patients in Tongren, China, reveals that human rhinovirus is the most prevalent respiratory pathogen overall, while infection rates for influenza A, B, and Mycoplasma pneumoniae increase with age, and distinct seasonal peaks exist for each of the six common pathogens, highlighting the need for age- and season-specific prevention strategies.

Yan Yang, Hongyan Wang, Li Long, Yaling Li, Dijia Liu, Jinshuai Wang2026-10-13
📄 medicine

Clinical Analysis of Rare Chylous Mesenteric Cyst in Children

This retrospective study of eight pediatric patients demonstrates that while preoperative diagnosis of chylous mesenteric cysts remains challenging, laparoscopic surgery—either via cyst excision or en bloc resection—proves to be a safe and effective treatment option with favorable short- and medium-term outcomes.

Yinan Hong, Huazhe Wu, Weiming Chen, Yangming Chen, Qiuju Wang, Chunwei Su, Hongbiao Zeng, Yongjuan Wei2026-10-13
📄 medicine

Preventive anti-inflammatory and osteoprotective effects of the FAAH inhibitor URB597 in a rat model of LPS-induced periodontitis

Topical application of the FAAH inhibitor URB597 exerts significant preventive anti-inflammatory and osteoprotective effects in a rat model of LPS-induced periodontitis by reducing alveolar bone loss, inflammatory mediators (TNFα and PGE2), and MMP activity.

Julieta R. Rodas, Gaston R. Troncoso, Julia I. Astrauskas, Florencia Núñez, Claudia E. Mohn, Cesar A. Ossola, Javier Fer (…)2026-10-13
📄 medicine

Lung Scintigraphy for Suspected Pulmonary Embolism During Pregnancy: Fetal Radiation Dose and Pregnancy, Neonatal, and Childhood Outcomes

This retrospective study of 44 pregnant patients suggests that lung scintigraphy for suspected pulmonary embolism delivers a low fetal radiation dose and is associated with generally reassuring pregnancy and childhood outcomes, though definitive conclusions about long-term safety are limited by the small sample size and lack of a control group.

Evrim Sürer Budak, Gül Alkan Bülbül, Tuğçe Acar Tunç, İbrahim İnanç Mendilcioğlu2026-10-13
📄 medicine

Variability in Resting Oxygen Consumption Estimation in Adult Patients After Fontan Operation

This study demonstrates that in adult Fontan patients, resting oxygen consumption (rVO₂) varies significantly depending on the estimation method, with indirect calorimetry providing the most accurate values and predictive equations or CPET-derived estimates potentially leading to substantial errors in hemodynamic calculations like pulmonary vascular resistance.

Jure Dolenc, Aljoša Kuzmanovski, Evgen Benedik, Nejc Pavšič2026-10-13