4098 papers
This study demonstrates that both low- and high-frequency electrical stimulation of the olfactory bulb effectively alleviates kindled seizures and restores memory in rats by modulating synaptic currents and normalizing gene expression, suggesting the olfactory bulb is a viable deep brain stimulation target for epilepsy treatment.
This study utilizes a discrete choice experiment to reveal that Chinese cancer patients prioritize favorable physician ratings, chief physician consultations, and specific digital features over cost, providing evidence for optimizing telemedicine services through high-quality provider engagement, insurance integration, and differentiated service models.
This prospective non-randomized interventional study demonstrates that Photobiomodulation Therapy is more effective than conventional care in reducing the severity of chemoradiotherapy-induced oral mucositis, alleviating pain and burning sensations, and improving nutritional status in head and neck cancer patients.
This study developed and validated a modified Technology Acceptance Model instrument incorporating implementation-related factors, which demonstrated satisfactory psychometric properties for assessing digital public health intervention acceptance among nurses in Kenya.
This prospective study demonstrates that point-of-care ultrasound and neck radiography offer complementary diagnostic strengths for laryngotracheal stenosis, with ultrasound excelling at the glottis and radiography at the thoracic inlet, suggesting a combined, anatomy-guided triage pathway could improve airway assessment in resource-limited settings where CT is unavailable.
The OPTIMISE study developed a comprehensive framework of three guiding principles and seven practical domains to help researchers design accessible clinical trial consent processes that overcome communication and decision-making barriers for people with impaired capacity.
This pilot study demonstrates that cervical Er:YAG laser treatment yields superior colposcopic regression and HPV clearance rates compared to silicon dioxide-based vaginal gel in managing low-risk cervical dysplasia, while also offering a more immediate resolution than expectant management despite a small risk of progression in the latter group.
This retrospective study of 203 kidney transplant recipients in Ethiopia reveals a high burden of post-transplant infections, predominantly bacterial and most frequent within the first year, with residence in Addis Ababa identified as a significant associated factor.
This multicenter real-world study in Colombia found that while topical ketorolac and nepafenac prophylaxis for early-stage retinopathy of prematurity were associated with lower costs and, in the case of ketorolac, higher quality-adjusted life-years compared to surveillance alone, the results do not yet support routine adoption and highlight the need for well-powered randomized trials.
This prospective cohort study suggests that combining rifaximin with probiotics may offer superior long-term improvements in stool consistency and frequency for adults with functional diarrhea compared to probiotics alone, though these exploratory findings warrant confirmation through randomized controlled trials.