4098 papers
The EAGER-2 study is a multicenter, participant-blinded, sham-controlled randomized trial designed to validate the efficacy of electro-acupuncture combined with adjuvant chemotherapy in improving disease-free survival and other clinical outcomes for gastric cancer patients following gastrectomy.
This cross-sectional ExWAS study of over 41,000 US individuals aged 2–25 identified 91 dietary and chemical exposures associated with overweight, highlighting that while most consistent factors were linked to lower odds (such as fiber, copper, and folates), few were consistently associated with higher odds (notably gamma tocopherol and cotinine).
This study utilizes Finite Element Analysis to demonstrate that a novel palatal TAD-supported distalizer applying equal forces to both the first and second maxillary molars yields more uniform stress distribution, greater bodily displacement, and superior vertical control compared to an appliance applying force solely to the first molar.
This cross-sectional study of over 5,700 middle-aged and older Chinese women reveals that higher parity and a younger age at first birth are independently associated with lower cognitive function, supporting the maternal depletion hypothesis.
In the CAR-T therapy era, patients with bulky relapsed/refractory diffuse large B-cell lymphoma experience worse overall survival compared to non-bulky patients, though the combination of autologous hematopoietic stem cell transplantation and CAR-T significantly improves outcomes for both groups.
This study demonstrates that quantitative assessment of atrial distensibility is a significant predictor of short-term perinatal adverse outcomes in fetuses with single ventricle-type congenital heart disease and moderate-to-severe atrioventricular valve regurgitation.
This study demonstrates that implementing clinical pharmacy services, specifically medication reviews and pharmaceutical interviews, in a pediatric cardiology department is feasible and effective in identifying significant medication-related problems and enhancing the safe use of high-risk medications for vulnerable young patients.
This retrospective cohort study in South Africa reveals that while socioeconomic status does not directly predict laryngotracheal stenosis outcomes, it significantly influences the etiology of the disease, which in turn mediates clinical severity and treatment success through a mechanism termed "aetiological embedding of social determinants."
This study introduces and validates the CT-based SPA-CE classification system for glenoid bone loss in reverse shoulder arthroplasty, demonstrating its utility as a treatment-oriented framework that correlates specific defect patterns with appropriate reconstructive strategies and offers greater morphological detail than existing systems like Walch.
This study demonstrates that the expression of neutrophil extracellular trap (NET) components (CitH3, MPO, and NE) in colonic mucosa is significantly elevated in pediatric Crohn's disease and positively correlates with disease activity, suggesting their potential as biomarkers for assessing disease severity.