4098 papers
This prospective-retrospective study demonstrates that patient-specific mathematical planning of trocar placement and instrument angles, combined with local hemostatic optimization, significantly reduces conversion rates, repositioning needs, and complications compared to conventional four-port laparoscopic cholecystectomy for acute calculous cholecystitis.
This case report from Brazil illustrates how integrated, trauma-informed, and gender-affirming multidisciplinary care can effectively support a transmasculine twin pregnancy complicated by homelessness, sexual violence, and high-risk obstetric conditions, emphasizing that clinical safety relies on addressing both medical needs and the cumulative effects of social vulnerability.
This systematic review of 26 studies establishes Galectin-9 as a multicompartment regulator of immune resistance in pancreatic ductal adenocarcinoma that drives disease progression through diverse mechanisms but currently lacks the clinical validation and standardized biomarkers necessary for high-translational maturity.
This study demonstrates that analyzing the interrelationships between 44 rat arterial pulse waveform parameters, particularly their differential responses to NO signaling compared to systolic blood pressure, provides a sensitive method for characterizing cardiovascular signaling pathways and distinguishing between hypertensive and normotensive conditions.
This experimental study with 1,200 UK adults demonstrates that positive influenza self-test results significantly increase intentions to seek healthcare and reduce transmission behaviors, while negative results decrease transmission-reducing intentions, highlighting the need for clear guidance to maximize public health benefits and minimize unintended consequences.
This study demonstrates that while insomnia is highly prevalent in adults with ADHD and linked to both internalizing and externalizing problems, it independently predicts internalizing symptoms even after accounting for core ADHD traits, with ADHD symptoms partially mediating this specific association.
This implementation research study in Sylhet, Bangladesh, aims to develop, optimize, and evaluate a Community-to-Facility Integrated Strategy (CFIS) using the WHO HEARTS-D module through a mixed-methods design and cluster-randomized trial to improve Type-2 diabetes control and prevention in urban low- and middle-income settings.
This cross-sectional study of 144 community-dwelling Chinese-speaking older adults in Australia reveals that functional ageing is characterized by a dominant, interconnected dimension of memory, executive function, sleep, and behavioral changes, suggesting that mood and sleep are modifiable targets for early intervention while highlighting the need for culturally responsive assessments.
This retrospective study demonstrates that the Systemic Immune-Inflammation Index (SII) significantly increases during spontaneous term labor and that elevated SII levels during labor serve as a practical predictive marker for postpartum hemorrhage.
This controlled study demonstrates that a midwife-led continuity of care model significantly reduces postpartum hemorrhage and cervical lacerations, improves labor pain management, and enhances maternal satisfaction compared to routine midwifery care for women undergoing vaginal delivery.