4098 papers
This cross-sectional study of 389 front-line nurses in China reveals a 45.0% prevalence of lower-limb work-related musculoskeletal disorders, identifying height, improper lifting techniques, and sustained twisted postures as significant risk factors while suggesting a healthy worker effect among those in departments with staff shortages.
This study evaluates the efficacy of four antiviral prototype drugs against α-, β-, and γ-herpesviruses using cell culture models, demonstrating that while individual treatments show varying potency, specific drug combinations like abemaciclib and LDC4297 exhibit robust synergistic effects across all three viral subfamilies, offering promising strategies for improved antiherpesviral therapy.
This nationwide analysis of U.S. emergency department data from 2020 to 2024 reveals a significant fourfold increase in electric-scooter–related head injuries, which occur at higher rates than other micromobility modes and pose a substantially elevated hospitalization risk for older adults, underscoring the urgent need for targeted prevention strategies.
This study demonstrates that high fibroblast activation protein (FAP) expression in hepatocellular carcinoma correlates with a proangiogenic and immunosuppressive tumor microenvironment characterized by VETC vascular patterns, reduced tertiary lymphoid structures, and poorer patient survival, suggesting FAP as a promising biomarker and therapeutic target.
This scoping review and SWOT analysis compares COVID-19 management for older adults in Cameroon and the United States, highlighting how Cameroon's reliance on community networks and pension support was undermined by structural healthcare deficits, while the US leveraged advanced data and vaccination systems but struggled with institutional inequities and misinformation, ultimately calling for tailored pandemic preparedness strategies that address the distinct economic and systemic challenges of both low- and high-income nations.
This paper describes the development and pilot evaluation of VIGIA, an automated clinical decision support tool that successfully prioritizes primary care patients with polypharmacy for medication review by integrating hospital admission risk prediction and pharmacotherapeutic inadequacy detection, demonstrating high feasibility and perceived utility among healthcare professionals.
This qualitative study of 14 Malaysian gastroenterologists reveals that probiotic prescribing is driven by mechanistic plausibility and patient-reported outcomes rather than high-certainty evidence, reflecting a cautious, trial-and-error approach shaped by regulatory ambiguity and a critical need for strain-specific guidelines.
This study utilizes a factorial modeling approach based on international guidelines to estimate population-specific dietary iron requirements for the Saudi population, providing essential data for nutritional assessment and policy development while accounting for physiological factors and dietary bioavailability.
This study demonstrates that altered cerebrospinal fluid amino acid homeostasis, particularly elevated aspartate and glycine, is significantly associated with oxidative stress and neuronal injury markers in multiple sclerosis, suggesting a composite metabolic profile that complements existing biomarkers for capturing disease activity.
This study describes the structured translation and adaptation of the 2022 American Academy of Geriatric Physical Therapy clinical practice guideline for osteoporosis management into a German version, creating an evidence-based resource for physiotherapists in German-speaking countries without altering the original therapeutic recommendations.