13909 papers
This hospital-based cross-sectional study conducted in Bangladesh reveals that poor sleep quality is highly prevalent among women with endometriosis and is significantly associated with pain-related symptoms such as dyspareunia, dysmenorrhea, and pelvic pain, highlighting the need for routine sleep assessments in clinical management.
Using 2024–2025 BRFSS data from 79,972 U.S. adults, this study finds that while perceived neighborhood safety does not influence whether households own firearms, living in perceived unsafe neighborhoods is significantly associated with a higher likelihood of storing firearms in a loaded and unlocked state.
This study presents a synergistic strategy using ultrasound-activated, protease-responsive microneedles loaded with piezocatalytic nanorods and CGRP to simultaneously eradicate bacterial biofilms, modulate the wound microenvironment, and restore neuroimmune signaling, thereby accelerating the regeneration of infected diabetic wounds.
This study demonstrates that a chitosan-based sublingual patch delivering a subunit influenza vaccine provides superior protection against infection in aged mice compared to traditional injections, likely by leveraging age-specific immune mechanisms involving enhanced B cell activation and neutrophil recruitment despite lower antibody levels.
This cross-sectional study of 2,452 Chinese adolescents reveals that higher resilience, along with shorter daily internet use and adequate sleep, serves as a protective factor against anxiety and depressive symptoms, highlighting the need for school-based resilience programs and lifestyle interventions.
This retrospective study of 638 patients identifies male sex, higher body mass index, neoadjuvant chemoradiotherapy, and mid-rectal tumor location as independent predictors of increased surgical difficulty in robotic-assisted rectal cancer surgery, providing a basis for improved preoperative risk stratification.
This study demonstrates that closed-loop neuromodulation provides safe, cumulative, and patient-specific seizure control for drug-resistant epilepsy through the plastic reorganization of local inhibitory microcircuits and suppression of long-range epileptic propagation, as evidenced by distinct intracranial gamma-band enhancements and scalp slow-wave changes.
This longitudinal study of older adults with hypertension and/or diabetes reveals that greater diversity in social participation, particularly engaging in three to four different activity types, is significantly associated with better long-term cognitive trajectories, whereas vigorous physical activity showed no significant link to cognitive function.
This retrospective study utilizing targeted next-generation sequencing identifies advanced age, elevated BMI, specific respiratory symptoms, and a distinct shift toward fungal and viral co-infections as key risk factors and pathogen profiles distinguishing severe from mild Influenza A(H1N1)pdm09 pneumonia.
This cross-sectional latent class analysis of over 189,000 U.S. adults aged 60 and older reveals that fall burden varies significantly across six distinct multidimensional profiles, demonstrating that functional, cognitive, mobility, and social characteristics are more predictive of fall risk than morbidity or cardiometabolic treatment status alone.