📄 medicine

Effect of Dolutegravir coMpared to Darunavir/Cobicistat, both with Tenofovir Disoproxil Fumarate/Emtricitabine, On the severity of neuRopsychiatric efFects at 24 weeks of treatment in people living with HIV and baseline nEuropsychiatric disorders with no prior antiretrOviral therapy experience (MORFEO)

In a phase IV trial involving treatment-experienced men with baseline neuropsychiatric vulnerabilities, the DRV/c-based regimen demonstrated superior longitudinal stabilization of depressive symptoms, sleep, and daytime functioning with fewer treatment discontinuations compared to the DTG-based regimen, despite both achieving comparable virological suppression at 24 weeks.

José Antonio Mata-Marín, Ana Luz Cano-Díaz, Emily Itzel Pecero-García, Mara Soraya Rodríguez-Evaristo, Paola Edith Padil (…)2026-10-12
📄 medicine

Comparison of Clinical and Structural Outcomes of the Combined Suture Bridge–Mason-Allen and Conventional Suture Bridge Techniques in Arthroscopic Rotator Cuff Repair: A Retrospective Comparative Cohort Study

This retrospective cohort study found that the combined suture bridge–Mason-Allen technique resulted in significantly lower 12-month retear rates and superior clinical outcomes compared to the conventional suture bridge technique for arthroscopic rotator cuff repair, although the non-randomized design warrants confirmation through prospective studies.

Ali Levent, Volkan Kızılkaya2026-10-12
📄 medicine

Women's Self-Reported Outcomes of Water Immersion for Labour and Birth in Australia: Findings from a National Cross-Sectional Survey

A national cross-sectional survey of 875 Australian women reveals that water immersion for labour and birth is a safe, acceptable, and valued option across diverse settings, characterized by high rates of vaginal birth, low intervention, and rare adverse events, thereby supporting the call for equitable access to this intrapartum care method.

Megan Cooper, Claire Feeley, Valerie Slavin, Ethel Burns, Bethan Townsend, Lauren Kearney2026-10-12
📄 medicine

Beyond Preference: Understanding Acceptability of Urine-Based HPV Screening in Rural Eswatini

This mixed-methods study in rural Eswatini finds that while urine-based HPV screening is highly acceptable due to its non-invasive nature, ensuring long-term adherence and community uptake requires addressing cultural stigma, misinformation, and structural barriers through the pivotal role of healthcare providers.

Francesca Squillace, Valentina Alice MUTTI, Paola Angelone, Sindi Nhleko, Tengetile Motsa, Simone Villa, Mzamo Sikhondze (…)2026-10-12
📄 medicine

Comparison of Short-term Efficacy and Exploratory Risk Factors for Early Complications of Airway Stenting in Benign and Malignant Airway Diseases

This study demonstrates that while airway stenting effectively alleviates dyspnea in both benign and malignant airway diseases, patients with malignant lesions face significantly higher rates of short-term complications, and repeated stent implantation is tentatively identified as an independent risk factor for adverse outcomes.

xia yang, Meihua Zhang, Xiaoping Xu, shuang zhao, penghao huang, jian sun2026-10-12
📄 medicine

Association between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and cardiovascular mortality among US adults with diabetes: a prospective cohort study of NHANES 1999–2018

This prospective cohort study of US adults with diabetes found a modest, nonlinear association between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and cardiovascular mortality, where higher NHHR values above an apparent nadir of approximately 2.5–3.0 were linked to an increased risk, though the findings warrant cautious interpretation and further validation.

Rui Lin, Yangbo Chen, Youde Liu, Yongjian Lin, Zexiong Li, Shangbo Xu2026-10-12
📄 medicine

HPV Knowledge, Vaccination Uptake, and Barriers to Vaccination among Healthcare Workers at a University Hospital in Türkiye: A Cross-Sectional Study

This cross-sectional study of 288 healthcare workers at a Turkish university hospital reveals a significant knowledge–behavior gap where, despite substantial HPV knowledge—particularly among physicians—vaccination uptake remains critically low at 6.2%, driven primarily by barriers such as lack of knowledge, low perceived risk, and cost, necessitating targeted institutional interventions for non-physician staff.

Ugur Demirkol, Giray Kolcu, Funda Yıldırım Baş2026-10-12
📄 medicine

Coping Styles of Primary Caregivers of Children with Acute Lymphoblastic Leukemia: Current Status and Influencing Factors

This study of 237 primary caregivers of children with acute lymphoblastic leukemia found that while most adopt active coping styles, factors such as employment status, income, residence, illness uncertainty, hope levels, social support, caregiving knowledge, and treatment complications significantly influence their coping strategies, suggesting a need for targeted interventions to support vulnerable caregivers.

Ronghua Wang, Yiming Zhang, Hui Yang, Yulin Fan, Xiaoyan Yu, Anwei Xie2026-10-12
📄 medicine

Deployable ultraviolet systems for environmental surface disinfection in healthcare: a scoping review linking dose delivery, room-scale performance and infection-prevention outcomes

This scoping review of 70 studies on deployable ultraviolet systems in healthcare concludes that while these devices consistently reduce environmental bioburden when accounting for factors like distance and shadowing, their impact on patient-level infection outcomes remains mixed and context-dependent, highlighting a critical need for future research to link dosimetry, environmental reduction, and clinical results within single evaluations.

Cristiano Salata, Ilenia Crozzoletti, Paola Brun, Claudia Del Vecchio, Ignazio Castagliuolo2026-10-12