📄 Category

medicine

4098 papers

📄 medicine

An Interpretable EHR-Derived Lactate–Hemodynamic Framework for Mortality Risk Stratification in ICU Sepsis: A MIMIC-IV Derivation and eICU Validation Study

This study demonstrates that an interpretable framework classifying ICU sepsis patients into four hypoperfusion phenotypes based on lactate, mean arterial pressure, and vasopressor use effectively stratifies mortality risk, with the combined hypoperfusion phenotype showing the strongest and most reproducible association with adverse outcomes across both MIMIC-IV and eICU cohorts.

Xinlei He, Mengyuan Shen, Yunhui Ni, Jianfei Sun, Weiwei Chen, Xiaoxiang Gao, Haibo Qiu2026-07-10
📄 medicine

Factors Associated with Healthcare Decision-Making Autonomy among Pregnant Women in West Africa

This study of 7,330 pregnant women across 12 West African countries reveals that healthcare decision-making autonomy remains low overall but is significantly higher among women who are older, educated, employed, and unmarried, while being lower in rural areas and specific countries like Mali.

Sarah Kyerewaa Obiri, Tausi Seleman Haruna, Bright Worlanyo Aklamanu, Henry Ofori Duah, Emmanuel Angmorteh Mensah, Derri (…)2026-07-10
📄 medicine

Wearable-Based Digital Metrics Reveal Dynamic Dissociations Between Upper Limb Capacity and Real-World Use Over the First Six Months After Stroke

This study of 70 stroke patients demonstrates that while upper limb clinical capacity and real-world use are initially correlated, they decouple over time, with performance plateauing earlier and improving through distinct mechanisms, indicating that gains in clinical ability do not automatically translate to increased daily arm use.

Eva Josse, Hsiao-Ju Cheng, Lay Fong Chin, Clara XJ Soh, Christopher W. K. Kuah, Megan SE Lau, Chwee Yin Ng, Tegan K. Plu (…)2026-07-10
📄 medicine

Stage Shift Following Implementation of a Comprehensive Lung Cancer Identification Program using Blood-Based Biomarkers in a U.S. Community Health System

This retrospective study demonstrates that implementing a multidisciplinary lung cancer identification program (CLIP) integrating structured nodule tracking, screening coordination, and blood-based biomarkers in a U.S. community health system was associated with a significant shift toward earlier-stage lung cancer diagnoses and a reduction in advanced-stage presentations.

Maurice A. Smith, Rachel Rogalski, Andrew Rogalski2026-07-10
📄 medicine

Diversity-inclusion gap in orthopedic surgery: a nationwide cross-sectional survey among Dutch surgeons and residents

This nationwide Dutch survey reveals a "diversity-inclusion gap" in orthopedic surgery, where increased diversity among residents and junior doctors does not translate to positive perceptions of work culture or satisfaction with inclusion, highlighting the urgent need to foster an inclusive environment beyond mere representation.

Maud Kramer, Karen D Könings, Jasper M Most, Edwin JP Jansen, Ide C Heyligers2026-07-10
📄 medicine

Secular trends in physical fitness between 2004 and 2022 in Belgian children aged 10–12 years: findings from a long-term school-based surveillance program

A long-term surveillance study of over 70,000 Belgian children aged 10–12 revealed significant secular declines between 2004 and 2022 in most physical fitness parameters, including cardiorespiratory endurance, speed, flexibility, and lower-limb strength, underscoring the urgent need for targeted public health interventions.

Amélie Brau, Marc Cloes, Gabriel Bailly, Boris Jidovtseff, Alexandre Mouton, Anne-Marie Fontaine, Bruno Meunier, Vivian (…)2026-07-10
📄 medicine

Functional Performance Assessment in Older Adults With Parkinson’s Disease: Reliability and Validity of the One-Minute Sit-to-Stand Test

This study demonstrates that the One-Minute Sit-to-Stand Test is a reliable and valid tool for assessing functional performance in older adults with Parkinson's disease, showing strong correlations with established measures and excellent test-retest consistency.

İsmail Ceylan, Muhammed Samed Dalakçı, Mehmet Canlı, Büşra Kürtüncüoğlu, Meltem Yücel Ilgar, Büşra Aydın, Halil Alkan, İ (…)2026-07-10
📄 medicine

Pregnancy Care and Access Among Black-African and Black-Caribbean Medically Uninsured Pregnant People Attending a Toronto Walk-In Clinic: A 10-Year Retrospective Chart Review

This 10-year retrospective chart review of a Toronto walk-in clinic reveals that medically uninsured Black-African and Black-Caribbean pregnant people face significant structural barriers to care, characterized by delayed prenatal entry, fragmented documentation, and higher anemia rates compared to non-Black participants, underscoring the critical role of integrated midwifery models in mitigating these inequities.

Manavi Handa, Shani Robertson2026-07-10
📄 medicine

A case of Encapsulated Papillary Carcinoma of the Breast in an Elderly Male with Unusual Presentation

This paper reports a rare case of encapsulated papillary carcinoma of the breast in an 80-year-old male, characterized by an unusual two-year history of a breast lump and nipple ulcer, which was successfully treated with a simple mastectomy and confirmed via P63 immunohistochemical staining.

Ishaku Agahu Othman, Mudashiru Biodun Lawal, Oseyimawa Mosugu, Horace Ojobo Agada, Barka Vandi Kwaghe, Andrea Oludolapo (…)2026-07-10
📄 medicine

Feasibility of the use of Group Interpersonal Psychotherapy in schools to treat depression among adolescents in Uganda. A qualitative study

This qualitative study in Uganda demonstrates that Group Interpersonal Psychotherapy (IPT-G) is a feasible and beneficial intervention for treating adolescent depression in school settings, provided that implementation challenges regarding scheduling and teacher workload are addressed through administrative support and flexibility.

Elly Atuhumuza, Khamisi Musanje, Roscoe Kasujja, Jacquellyn Nambi Ssanyu, Andrew Fraker, Shakirah Nakalungi, Morris Ndee (…)2026-07-10