4102 papers
This paper reports a rare case of encapsulated papillary carcinoma of the breast in an 80-year-old male, characterized by an unusual two-year history of a breast lump and nipple ulcer, which was successfully treated with a simple mastectomy and confirmed via P63 immunohistochemical staining.
This qualitative study in Uganda demonstrates that Group Interpersonal Psychotherapy (IPT-G) is a feasible and beneficial intervention for treating adolescent depression in school settings, provided that implementation challenges regarding scheduling and teacher workload are addressed through administrative support and flexibility.
This longitudinal study reveals that PD-1 inhibitor-based immunochemotherapy in patients with lung and colorectal cancer induces selective, progressive alterations in pituitary hormones (specifically increasing FSH and prolactin while decreasing the LH/FSH ratio) without causing significant changes in circulating gonadal sex steroids, suggesting a primary pituitary-level endocrine response rather than overt gonadal dysfunction.
This qualitative study within the TOGAS project reveals that communicatively vulnerable adults in Belgium and the Netherlands prefer non-invasive gastric cancer screening methods like breath tests and rely heavily on healthcare providers' recommendations, while facing significant barriers related to language, low health literacy, and the need for tailored educational support.
This cross-sectional study of 350 children with measles in Sana'a, Yemen, reveals alarmingly low vaccination coverage (with 75.43% unvaccinated) driven primarily by caregiver fears, paternal refusal due to rumors, geographical barriers, and maternal illiteracy, underscoring the urgent need for targeted health education and localized immunization campaigns to address these critical determinants.
This study demonstrates that combining preoperative enhanced CT with the immunohistochemical expression of VEGF-C, CK20, and PYCR1 significantly improves the diagnostic accuracy for predicting lymph node metastasis in patients with muscle-invasive bladder urothelial carcinoma compared to CT alone.
This case report demonstrates that a single intravitreal bevacizumab injection successfully resolved persistent subretinal fluid and metamorphopsia in a patient with chronic central serous chorioretinopathy who failed medical therapy and was unsuitable for laser treatment, suggesting it as a viable rescue option for selected cases.
This nested sequential explanatory mixed-methods study of Black women in Alachua County, Florida, identifies specific demographic factors associated with medical mistrust in reproductive care and highlights five key provider characteristics—transparency, humanizing interactions, comfort, acknowledgment of patient insight, and time—that are essential for building trust, ultimately calling for structural and interpersonal interventions to support Black women and reduce their need for self-advocacy.
This study demonstrates that suppressing PD-L1 expression via siRNA sensitizes CaSki cervical cancer cells to Paclitaxel by enhancing apoptosis, inhibiting migration and colony formation, and reducing the effective drug dose, suggesting a promising combined therapeutic strategy for cervical cancer.
This case report describes a rare instance of cardiac arrest caused by tension pneumopericardium resulting from an esophago-pericardial fistula due to a sharp foreign body, which was successfully managed through emergent pericardiocentesis, endoscopic foreign body removal, and surgical intervention.