13909 papers
This case report describes a rare instance of primary malignant peripheral nerve sheath tumor of the vagina in a 67-year-old woman, highlighting its aggressive nature through rapid local recurrence and distant metastasis one year after surgery despite initial complete resection, thereby underscoring the critical need for adjuvant therapy and rigorous long-term surveillance.
This national case-crossover study utilizing Brazilian and MIMIC-IV data demonstrates that while extreme temperatures modestly affect the volume of myocardial infarction admissions, they do not shift the severity of cases toward intensive care or death, and it further validates that ICU stays are a more reliable marker of clinical severity than diagnostic codes.
This retrospective chart review of 300 breast cancer patients at Rwanda's Butaro Cancer Centre of Excellence reveals that the majority are diagnosed at a younger age with a high burden of modifiable risk factors and comorbidities, and nearly half present with late-stage disease, underscoring the urgent need for enhanced early-detection strategies in resource-limited settings.
This constructivist grounded theory study of family medicine residency programs in Brazil reveals that evaluative misalignment between residents and preceptors stems from divergent reasoning rather than scoring discrepancies, leading to the development of the S-SKILLS-F framework to transform feedback into a negotiated, actionable process for professional growth.
This study protocol outlines the participatory development, iterative testing, and evaluation of a personalized activity book designed to age-appropriately prepare primary school-aged children for inpatient medical rehabilitation by involving children, parents, and professionals in its creation.
This hospital-based case-crossover study in Kinshasa (2018–2022) provides the first clinical evidence that short-term increases in PM₂.₅ concentrations are significantly associated with higher rates of acute respiratory admissions among adults, particularly those aged 35–64, highlighting the urgent need for improved air quality surveillance and environmental health integration in sub-Saharan Africa.
This study demonstrates that lower third-trimester placental vascular index in the mid-region (VIMed), measured via MV-Flow ultrasound, is significantly associated with adverse perinatal outcomes in gestational diabetes mellitus and enhances the predictive accuracy of a risk-stratification model when combined with pre-pregnancy BMI and fasting OGTT glucose.
Using data from the MIDUS study, this research demonstrates that social well-being, distinct from other dimensions of subjective well-being, is prospectively associated with a slower pace of multisystem biological aging as estimated by a novel single-scan brain MRI biomarker.
This cross-sectional study of 534 psoriatic adults reveals that ultrasound-detected hepatic steatosis affects approximately one-quarter of patients, is primarily driven by central adiposity rather than skin or joint severity, and often occurs despite normal aminotransferases, suggesting gamma-glutamyl transferase (GGT) as a promising secondary marker for detection.
This study demonstrates that while Retrieval-Augmented Generation (RAG) significantly enhances the consistency and stability of AI responses to pediatric dentistry guideline questions compared to standalone models, it does not fully eliminate systematic evidence-mapping errors, suggesting that future AI evaluations must prioritize reliability frameworks over simple accuracy metrics.