📄 Category

medicine

4248 papers

📄 medicine

Early One-Cycle Post-Neoadjuvant Chemotherapy Volumetric and SER-based Changes on DCE-MRI: Timely Predictors of Response and Prognosis in Breast Cancer

This study demonstrates that early volumetric and signal enhancement ratio-based functional tumor volume reductions observed on DCE-MRI after just one cycle of neoadjuvant chemotherapy serve as superior predictors of clinical response and recurrence-free survival compared to traditional size-based metrics or later assessments in breast cancer patients.

Alisa Mohebbi, Mehrad Zare, Zahra Moradi, Afshin Mohammadi2026-07-10
📄 medicine

Repeated PEFR-defined probable respiratory sarcopenia and incident frailty among middle-aged and older Chinese adults: a longitudinal CHARLS study

This longitudinal study of Chinese adults found that experiencing probable respiratory sarcopenia at least once during follow-up is associated with an increased risk of developing incident frailty, suggesting that PEFR-based screening serves as a useful population-level signal for frailty risk despite non-monotonic patterns across repeated measurements.

Qi Wang, Yasuo Ding, Yanhua Xu, Hongmei Wang2026-07-10
📄 medicine

Concurrent Pneumocystis jirovecii pneumonia and Guillain-Barre syndrome after surgery and adjuvant chemoradiotherapy for stage IIIA lung adenocarcinoma: a case report and literature review

This case report describes a rare instance of concurrent Pneumocystis jirovecii pneumonia and Guillain-Barré syndrome in a lung cancer patient following chemoradiotherapy, emphasizing the critical need for early, multi-modal diagnostic assessment to distinguish overlapping infectious and immune-mediated complications from treatment-related toxicity.

Hai-Bo Cai, Hui-Bin Chen, Jing-Hui Wang, Wen-Yu Wu, Dong-Xin Tang2026-07-10
📄 medicine

Asymptomatic Giant Tubulocystic Retroperitoneal Lymphangioma with Significant Compression of the Ascending Colon: A Case Report

This case report describes a rare instance of a giant, asymptomatic tubulocystic retroperitoneal lymphangioma in a 47-year-old woman that was successfully treated with complete surgical excision despite significant mass effect on the ascending colon, highlighting the importance of considering intervention for large cystic lesions even in the absence of symptoms.

Qi Xie, Xiao Xu2026-07-10
📄 medicine

Comparative Analysis of MMP-1 and α-SMA Expression in Ventral and Dorsal Dartos Tissue of Patients With Hypospadias and Chordee

This study demonstrates that ventral dartos tissue in patients with hypospadias and chordee exhibits significantly lower MMP-1 and higher α-SMA gene expression compared to dorsal tissue, suggesting that regional molecular differences in extracellular matrix remodeling and fibrotic activity contribute to penile curvature.

JOKO PITOYO, Alvarino Alvarino, Afdal Afdal, Indra Jaya, Muhammad Adan Yashar, Naura Alifa Daniesya Pitoyo2026-07-10
📄 medicine

Characterising Occupational Noise Profiles and Workspace Risk Associations across Five Distinct Informal Sectors

This study reveals that workers in five informal sectors in Benin City, Nigeria, face catastrophic noise exposure levels far exceeding safety limits, with multivariable models identifying mechanical processing environments like sawmills, abattoirs, and the vibrating block industry as independent predictors of severe hearing difficulties, chronic stress, and tinnitus, while highlighting a significant health literacy bias in symptom reporting among lower-educated operators.

Aimuanmwosa Frank Eghomwanre, Efosa Bethel Omomagiowawi, Chinonso Patience Okoh, Favour Reuben, Sonia Okungba, Benedicta (…)2026-07-10
📄 medicine

Incidental Moderate Aortic Stenosis and 90-Day Mortality in Non- Cardiac Critical Illness: A Retrospective Cohort Study Using the MIMIC-IV Echocardiography Database

In a retrospective cohort study of non-cardiac critical illness patients using the MIMIC-IV database, incidentally detected moderate aortic stenosis was found to be independently associated with a modest but consistent increase in 90-day mortality, suggesting it serves as a marker of elevated short-term risk rather than a direct target for immediate valve intervention.

Lujun Shao, Cheng Xu, Huiyu Tai, Yue Li2026-07-10
📄 medicine

Hidden Barriers and Operational Gaps in Emergency Evacuation Equipment Design Requirements for Bed-dependent Patients: A Qualitati­ve Study in Iran

This qualitative study conducted in Iran identifies critical operational gaps and design mismatches in current emergency evacuation equipment for bed-dependent patients, revealing an urgent need for indigenous, lightweight, and manually powered solutions adapted to local infrastructure and resource constraints.

rasoul fattahipour, Maryam Azizi, Simintaj Sharififar, Hamid Reza Khankeh, Fatemeh Teymouri2026-07-10