📄 medicine

Predictors of fertility-limiting preferences among currently married women in Bangladesh: an interpretable machine learning analysis of the 2022 Demographic and Health Survey

Using interpretable machine learning on 2022 Bangladesh Demographic and Health Survey data, this study demonstrates that XGBoost can accurately predict fertility-limiting preferences among married women, identifying age, number of living children, and contraceptive intention as key predictors while revealing that digital inclusion and mental health have minimal influence.

Md. Mahbub-Ur Rashid, Prayas Sur Antu, Ujjoyene Talapatra Athai, Md. Hazrat Ali2026-10-11
📄 medicine

Snowman-like appearance in spinal capillary hemangioma with combined intra- and extramedullary components: two case reports

This paper reports two rare cases of spinal capillary hemangioma with combined intra- and extramedullary components presenting a "snowman-like" MRI appearance, highlighting the importance of including this benign tumor in the differential diagnosis for such imaging patterns despite its typical association with hemangioblastoma.

Takeshi Kidoguchi, Shingo Tanaka, Mitsutoshi Nakada2026-10-11
📄 medicine

Early-Onset Rectal Adenocarcinoma as the Initial Manifestation of Li- Fraumeni Syndrome Associated with a Germline TP53 p.R337H Variant: A Case Report and Literature Review

This case report describes a 34-year-old male with early-onset rectal adenocarcinoma and a strong family cancer history who was diagnosed with Li-Fraumeni Syndrome via the identification of a germline TP53 p.R337H variant, highlighting the critical need for genetic evaluation in young colorectal cancer patients.

Ashkan Torshizian, Lena Goshayeshi, Seyedeh Helia Seyedzadegan Halaj, Nastaran Khoshhal, Maliheh Alimardani, Mohammad Re (…)2026-10-11
📄 medicine

Six-Weekly Low-Dose Nivolumab Combined with Oral Triple Metronomic Chemotherapy for Advanced Cancers of the Head and Neck: An Open-Label, Prospective, Single-Institution Experience from Eastern India

This open-label, single-institution study from Eastern India demonstrates that a six-weekly low-dose regimen of nivolumab combined with oral metronomic triple chemotherapy (methotrexate, erlotinib, and celecoxib) achieves overall survival and progression-free survival comparable to standard immunotherapy schedules in advanced head and neck squamous cell carcinoma, while offering a more affordable, less disruptive, and well-tolerated treatment option with no immunologic adverse events or treatment-attributable deaths.

Santosh Kumar Swain, Soumya Surath Panda, Lalatendu Moharana, Lipsita Samantaray, Abinash Patnaik, Swati Sucharita Mohan (…)2026-10-11
📄 medicine

Impact of bipolar versus holmium laser enucleation on sexual function in men with prostate > 60 g: a prospective two-center randomized controlled trial

In a prospective randomized trial of men with large prostates (>60 g), bipolar and holmium laser enucleation demonstrated comparable erectile function recovery at six months, though bipolar enucleation was associated with superior ejaculatory outcomes.

Mohamed Abdelrahman Alhefnawy, Ahmed Desouky, Ahmed Abul Fotouh Eid, Mohamed Abdelzaher2026-10-11
📄 medicine

Effectiveness of a Nurse-Led Online Health Education Programme on Empowerment, Pain Catastrophizing, and Perceived Health Improvement in Women with Endometriosis: A Longitudinal Quasi-Experimental Study

This longitudinal quasi-experimental study demonstrates that a nurse-led online health education programme significantly and sustainably improves patient empowerment and reduces pain catastrophizing among women with endometriosis over a 12-month period, while maintaining high levels of patient satisfaction.

Georgina Feixas, Marta Garcia, Sandra Parés, Lara Quintas-Marquès, Meritxell Gracia, Mariona Rius, Francisco Carmona, Ma (…)2026-10-11
📄 medicine

Preoperative prediction and perioperative risk updating for adjacent vertebral fracture after percutaneous vertebroplasty: development and internal validation of a two-stage prediction strategy

This study developed and internally validated a two-stage prediction strategy for adjacent vertebral fracture after percutaneous vertebroplasty, demonstrating that a six-predictor preoperative model effectively estimates risk while perioperative cement distribution data provides additional prognostic value with minimal improvement in discrimination.

Linyang Song, Yingnan Li, Xin Liu, Hengfei Qiu, Yanting Wang, Zhiyong Ren, Guangjun Jiao2026-10-11
📄 medicine

Safety and Acceptance of a Relaxed Gluten-Free Diet in Celiac Disease: Protocol for a Mixed Methods Pilot Randomized Controlled Trial

This protocol outlines a mixed-methods pilot randomized controlled trial designed to evaluate the histological safety and patient acceptance of a relaxed gluten-free diet permitting up to 200 ppm gluten cross-contact compared to a strict diet in adults with celiac disease over 24 weeks.

Diana Studerus, Jonas Zeitz, Vanessa Dürr, Nadine Bosbach, Ewerton Marques Maggio, Lauren Clack, Michael Scharl2026-10-10
📄 medicine

Pseudoangina as an Unusual Presentation of Non-Osseous Arterial Thoracic Outlet Syndrome: A Case Report.

This case report describes a rare instance of non-osseous arterial thoracic outlet syndrome presenting as pseudoangina in a young man, highlighting the critical need for high clinical suspicion and dynamic vascular imaging to diagnose the condition when cardiac causes are excluded and osseous abnormalities are absent.

Manish Singh, Puneet Saxena, Simple Gupta, Deepu K Peter, Rahul Dudhal2026-10-10