📄 medicine

Clinical-Prompt-Enhanced Deep Learning Model for Precise Preoperative Prediction of Gallbladder Polypoid Lesion Subtypes

This study presents GB-DualmodalNet, a clinical-prompt-enhanced deep learning framework that integrates preoperative ultrasound images with natural language-processed clinical data to accurately predict gallbladder polypoid lesion subtypes, thereby improving diagnostic performance over image-only models and reducing unnecessary cholecystectomies.

Qingyu Tang, Zhibo Wang, Zhenqi Tang, Hengchao Liu, Hongzhan Wang, Yubo Ma, Jiashu Song, Kangpeng Li, Minghui Dou, Ziyan (…)2026-07-09
📄 medicine

Development and validation of a sarcopenia screening scale for community-dwelling older adults in China: A risk score model based on multivariate logistic regression

This study developed and validated a simple, seven-point risk scoring scale based on five independent factors (age, lifting/carrying ability, maximum walking distance, finger-ring test, and mood status) to effectively screen for sarcopenia among community-dwelling older adults in China using the 2025 AWGS criteria, demonstrating good discrimination, calibration, and clinical utility for primary care settings.

Jing Xu, Can Duan, Zhengliang Li, Xi Sun, LingZhi Wang, Min Yang, Wenguang Xia, Chanjuan Zheng2026-07-09
📄 medicine

Early prediction of weaning trajectories and outcomes with machine learning in patients receiving Invasive Mechanical Ventilation in the WEAN SAFE cohort

This study demonstrates that machine learning models, particularly TabICL and TabPFN, can effectively predict weaning trajectories and extubation success in mechanically ventilated patients early in the weaning process by leveraging clinically meaningful and potentially modifiable factors such as organ dysfunction, frailty, and sedation state.

Nadeem Iqbal Kajla, Reginald Caldecott, Emma Urquhart, Bairbre McNicholas, Taï Pham, Leo Heunks, Giacomo Bellani, Lauren (…)2026-07-09
📄 medicine

When drugs speak: an exploratory convergent mixed-methods study of a first- person creative narrative activity for anti-seizure medication pharmacology in undergraduate medical education

This exploratory convergent mixed-methods study demonstrates that a zero-cost, first-person creative narrative activity ("When Drugs Speak") significantly enhances undergraduate medical students' engagement, retention, and conceptual understanding of anti-seizure medications by leveraging retrieval practice and elaborative encoding, as evidenced by high student preference and qualitative themes of narrative schema-building.

Divyashanthi Chellathambi Malathi, Kumaravel J, Dineshkumar Narayanasamy2026-07-09
📄 medicine

Preprocedural estimated glomerular filtration rate and all-cause mortality after TIPS in cirrhosis: a single-center retrospective cohort study

This single-center retrospective study of 618 cirrhosis patients found that a preprocedural eGFR below 60 mL/min/1.73 m² is associated with increased all-cause mortality after covered-stent TIPS, though this association is attenuated when adjusting for MELD scores, suggesting eGFR is a useful but non-independent marker for pre-TIPS risk assessment.

Han Cao, Jie Wu, Jun Shang, Yue-yue Liu, Zi-yi Wang, Rui-feng Wang, Chun-Ze Zhou2026-07-09
📄 medicine

Development of a Combined Risk Factors Prediction Model for Esophageal Squamous Cell Carcinoma: A Secondary Analysis of the Linxian Nutrition Intervention Trial Cohort

This study developed and validated a combined risk factor prediction model using data from the Linxian Nutrition Intervention Trial cohort, which effectively stratifies individual risk for esophageal squamous cell carcinoma based on eight independent factors to facilitate targeted early screening and prevention.

Huan Yang, Jingyi Shi, Jianbing Wang, Jinhu Fan, Shaokai Zhang, Yin Liu, Huifang Xu, Vikash Sewram, Jiangong Zhang, Fang (…)2026-07-09
📄 medicine

School-based high-intensity interval training improves classroom engagement more than moderate-intensity continuous training in children aged 8–9 years: a randomized controlled trial

In a randomized controlled trial involving 72 children aged 8–9, a six-week school-based high-intensity interval training (HIIT) program was found to improve objectively measured classroom engagement more effectively than moderate-intensity continuous training (MICT) or no exercise.

jialu Qin, chao chen, linjuan wang, hanyi li, zhen Zhang, jie Min2026-07-09
📄 medicine

Regimen-Specific Bowel Preparation and Early Postoperative C-Reactive Protein Elevation After Laparoscopic Hysterectomy: A Propensity Score-Matched Cohort Study

In a propensity score-matched retrospective cohort study of 1,238 patients undergoing laparoscopic hysterectomy, lactulose enema bowel preparation was associated with a significantly higher likelihood of early postoperative C-reactive protein elevation compared to mechanical enema, suggesting that bowel preparation regimens should be evaluated as specific exposures rather than a binary variable.

Yihan Zheng, Xizhu Wu, Longxin Zhang, Jing Wang2026-07-09