4321 papers
Incorporating L-arginine-containing mesoporous silica nanoparticles (ArgC18@MSNs) into a universal adhesive effectively preserves enamel microhardness against cariogenic challenges and prevents white spot lesions without compromising shear bond strength during orthodontic bracket bonding.
A national cross-sectional survey of Australian general practitioners reveals that while they are highly receptive to guideline-endorsed antenatal congenital cytomegalovirus screening and view it as feasible to implement, current inconsistencies in care and gaps in resources necessitate clear guidance, education, and referral pathways for successful adoption.
This systematic review and meta-analysis of 17 studies involving 1,241 eyes indicates that pedicled conjunctival rotational/transpositional flaps offer a comparable recurrence rate to free conjunctival autografts for pterygium surgery while providing shorter operative times and less graft edema, though they are associated with a higher risk of postoperative inflammation.
This mixed-methods systematic review of 11 studies from high-income countries finds that while health equity frameworks show promise in embedding equity across health systems through factors like Indigenous leadership and robust data, their sustained impact requires overcoming barriers such as policy instability and resource constraints via long-term organizational commitment and culturally legitimate governance.
This 2023 qualitative study evaluates the Pacific Public Health Surveillance Network through stakeholder focus groups, affirming its critical role as a trusted platform for regional health security while identifying key operational challenges such as communication delays, staff turnover, and funding transparency that require strategic improvement.
This prospective cohort study of older adults from NHANES 2011–2014 demonstrates that a higher hemoglobin-to-red blood cell distribution width ratio (HRR) is significantly associated with reduced all-cause mortality, with cognitive impairment—specifically deficits in processing speed—mediating approximately 19% to 21% of this protective effect.
This preclinical study demonstrates that the GSK-3β inhibitor 9-ING-41 significantly enhances the efficacy of chemoimmunotherapy in high-risk neuroblastoma models by promoting immune activation, leading to complete tumor regression and long-term survival in immunocompetent mice.
This meta-analysis reveals that contraceptive utilization among reproductive-age women with psychiatric disorders in sub-Saharan Africa is suboptimal at 47.63%, influenced by factors such as marital status, education, future childbearing intentions, physician counseling, knowledge, and fear of side effects, highlighting the urgent need for integrated mental and reproductive health services.
This five-year retrospective study of 1,511 ERCP procedures at a major Iranian tertiary center demonstrates high technical success and acceptable safety rates comparable to global benchmarks, while identifying a significantly higher risk of post-ERCP pancreatitis in female patients that warrants targeted prophylactic strategies.
This 10-year prospective study demonstrates that while serum E-selectin levels remain stable and show no association with disease progression in ADPKD, the AA genotype of the SELE S128R polymorphism is significantly associated with greater long-term increases in total kidney volume, cyst growth, and functional decline compared to AC and CC genotypes.