📄 medicine

3DAS: A Score to Evaluate the Fidelity of STL and Printed 3D Models: A Pilot Study

This pilot study introduces and validates the 3-Dimensional Accuracy Score (3DAS), a new composite metric for evaluating the anatomical fidelity of 3D-printed models and STL files, revealing that segmentation quality during DICOM-to-STL conversion is the primary source of error and highlighting the need for standardized verification in outsourced dental workflows.

David Pastorino, Aleix Solà, Catalin Caliniuc, Costa Nikolopoulos, Luc Vrielinck, Carlos Aparicio2026-07-08
📄 medicine

Onset Timing and Prognostic Value of Retinopathy of Prematurity Across Gestational Age Strata

This retrospective cohort study of 5,727 preterm infants in China demonstrates that postmenstrual age at first retinopathy of prematurity diagnosis is an independent prognostic marker for disease severity and retreatment burden, with the extremely low gestational age (<25 weeks) group facing significantly higher risks and a disproportionate need for multiple interventions, thereby supporting the adoption of gestational age-stratified screening schedules.

Jianxun Wang, Songfu Feng, Jing Li, Xiaohe Lu2026-07-08
📄 medicine

Development and External Validation of an Interpretable Machine-Learning Model for Predicting Synchronous Distant Metastasis in Invasive Bladder Cancer: A SEER Population-Based Study

This study developed and externally validated an interpretable machine-learning model using only clinical variables available at diagnosis to accurately predict synchronous distant metastasis in invasive bladder cancer, demonstrating superior performance over traditional TNM staging and offering a freely accessible online tool for individualized pre-treatment risk assessment.

Xiongwu Peng, Lingxing Duan, Xiongbing Lu2026-07-08
📄 medicine

The application of blood serum ATR-FTIR spectroscopy for the identification of Colorectal cancer

This study demonstrates that ATR-FTIR spectroscopy combined with machine learning analysis of blood serum can effectively distinguish colorectal cancer patients from healthy controls with high accuracy (90.9%), sensitivity (88.9%), and specificity (92.9%), offering a promising minimally invasive diagnostic tool.

wanli yang, nan pang, jia shi, wei zhang, Jin Han, ao song, Chao yang, Jun Leng, Degao Zhang2026-07-08
📄 medicine

Measuring What Future Physicians Know About Contraception: Development and Validation of the Clinical Contraceptive Knowledge Test (CCKT) in Vietnam Using Item Response Theory

This study developed and validated the 18-item Clinical Contraceptive Knowledge Test (CCKT-18) using Item Response Theory among Vietnamese medical students, demonstrating it to be a robust, unidimensional, and precise instrument for assessing contraceptive knowledge and guiding curriculum improvements.

Nguyen Dinh Ky, Nguyen Quynh Anh, Nguyen Ngoc Minh, Pham The Lam, Do Hoa Cham, To Khanh Linh, Nguyen Dang Linh Chi, Pham (…)2026-07-08
📄 medicine

Time to metastasis predicts prognosis and improves the Bellmunt score in metastatic urothelial carcinoma

This retrospective multicenter study demonstrates that time to metastasis (TTM) is an independent prognostic factor in metastatic urothelial carcinoma and that incorporating it into the Bellmunt score significantly improves risk stratification accuracy and clinical utility.

Tomoya Hatayama, Keisuke Goto, Yoshinori Nakano, Ryoken Yamanaka, Hiroyuki Shikuma, Shinsaku Tasaka, Naofumi Nomura, Yuk (…)2026-07-08
📄 medicine

Association between inhaler device type and therapeutic adherence in Belgium: a retrospective cohort study

This retrospective cohort study of over 77,000 Belgian adults demonstrates that inhaler device type is independently associated with therapeutic adherence, with dry powder inhalers (DPIs) showing significantly higher adherence rates compared to pressurised metered-dose inhalers (pMDIs) and soft mist inhalers (SMIs) across various pharmacological classes.

Amélie Rosière, Sebastian Riemann, Wies Kestens, Güngör Karakaya, Stéphanie Pochet, Guy Brusselle, Carine De Vriese2026-07-08
📄 medicine

The role of Artificial Intelligence in interventions to reduce alcohol consumption and smoking: A systematic review

This systematic review of randomized controlled trials in high-income countries found no strong evidence that artificial intelligence-assisted interventions effectively reduce alcohol consumption or smoking, largely due to mixed results, the inability to isolate AI's specific impact within multi-component interventions, and a high risk of bias across the included studies.

Sean Harrison, Claire Tatton, Joelle Kirby, Atandra Das, Sophie Robinson, Rhiannon Evans, Daniel Mutanda, Alisha Davies (…)2026-07-08