14263 papers
The STABLE trial, a prospective randomized controlled study, found that sustained breath-hold ventilation during tissue acquisition did not improve diagnostic yield or tool-lesion positioning compared to conventional ventilation in imaging-integrated robotic bronchoscopy for peripheral pulmonary lesions.
This cross-sectional study of community-dwelling older women reveals that an unstable gait phenotype characterized by slow speed, step length asymmetry, and high stride variability is significantly associated with an increased risk of femoral neck osteoporosis.
This realist evaluation of the Bergo'Bus rural cancer outreach programme reveals that while a single-visit format rarely translates into sustained individual screening participation, it effectively acts as a catalyst for community mobilization and strengthens local prevention capacity through mechanisms like trust, social proof, and cross-sector bridge-building.
This systematic review indicates that while corticosteroids are well-established for treating acute croup, evidence supporting their use in preventing hospital attendance and improving outcomes for children with recurrent croup remains limited and primarily observational, necessitating further prospective research to define optimal treatment regimens.
In a retrospective study of 182 children with Familial Mediterranean Fever, the Systemic Inflammation Response Index (SIRI) demonstrated the strongest but modest ability among CBC-derived indices to detect persistent subclinical inflammation, though disease severity remained the sole independent predictor, indicating that these indices cannot replace Serum Amyloid A testing.
This study developed and validated the PUTH classification system, a nerve root-centered framework for lumbar disc herniation that demonstrated substantial-to-excellent observer reliability and high agreement between preoperative MRI and intraoperative findings in patients undergoing percutaneous endoscopic lumbar discectomy.
This qualitative study of Dutch poultry farmers reveals that while many recognize the societal importance of seasonal influenza vaccination to prevent avian-human virus reassortment, uptake is hindered by government distrust, regulatory burdens, and perceived low personal risk, necessitating strategies that leverage trusted intermediaries and ensure accessible, voluntary vaccination programs.
This randomized controlled trial demonstrates that a multimodal opioid-sparing anesthesia strategy significantly improves postoperative quality of recovery and reduces pain and nausea compared to conventional opioid-based anesthesia in patients undergoing laparoscopic colorectal resection, although the authors note these benefits are partial and time-limited.
This scoping review of 33 studies involving 1,290 Indigenous adults with cancer identifies five interrelated domains of resilience—social support, spirituality, cultural continuity, culturally safe healthcare relationships, and individual strength—demonstrating that Indigenous cancer survival is rooted in collective social, cultural, and spiritual contexts rather than individual attributes alone.
This randomized controlled trial demonstrates that a brief, culturally adapted, nurse-led mindfulness-based cognitive therapy programme significantly reduced depressive symptoms and rumination while increasing mindfulness among Thai inpatients with depression compared to routine care alone, with benefits sustained at three months despite the study being underpowered to detect differences in readmission rates.