4376 papers
This study conducted in Southwest Nigeria during high malaria transmission season found that while the PfHRP2-based rapid diagnostic test demonstrated high sensitivity compared to PCR, its extremely low specificity and poor agreement with reference standards highlight significant limitations for routine clinical use.
This exploratory study of 100 households near Mumbai's Deonar landfill demonstrates that micro-environmental factors like drainage proximity and ventilation, rather than simple distance, create significant gradients in microbial exposure and respiratory health outcomes, supporting the need for zone-based assessment frameworks over conventional proximity models.
This national analysis of the 2023–2024 Nigerian Demographic and Health Survey reveals that while diabetes screening rates are modest, diagnosis and treatment uptake remain critically low with significant sociodemographic disparities, highlighting an urgent need to expand routine screening and strengthen primary care in Nigeria.
This retrospective cohort study of 382 patients with obstructive colon cancer found that while using self-expandable metallic stents as a bridge to surgery resulted in comparable overall survival, it was associated with significantly worse recurrence-free survival and a higher rate of liver-specific recurrence compared to non-stent management.
This mixed-methods study evaluates the Shared Community Follow-up model for germ cell tumours, finding that while integrating remote patient-reported outcomes with community-based care is feasible, safe, and valued by stakeholders, its successful scalability requires addressing challenges related to workforce capacity, technological infrastructure, and inter-centre communication.
This case series highlights the overlapping clinical and neuroimaging features of MELAS, CAA-ri, and anti-GABA_A receptor encephalitis while demonstrating that a multimodal diagnostic approach integrating specific imaging patterns, genetic testing, and antibody assays is essential for accurate differentiation and treatment.
This study identifies and optimizes hydroxamic acid compounds, particularly TI-801, as potent inhibitors of the essential *Mycobacterium tuberculosis* enzyme AlaA, demonstrating that inducing alanine auxotrophy via this target effectively kills the bacteria both intracellularly and in a murine infection model.
This 2024–2025 mixed-methods study of 2,107 Swedish medical students reveals that a majority support the legalization of physician-assisted dying, a stance strongly influenced by ethical frameworks prioritizing autonomy and religious beliefs rather than by the specific terminology used, while highlighting significant polarization and concerns regarding mandatory participation.
This retrospective pilot study demonstrates that combining intraoperative submucosal triamcinolone acetonide injection with a short course of oral prednisone is a safe and effective strategy for significantly reducing the incidence of esophageal stricture following endoscopic submucosal dissection for circumferential superficial tumors.
This study demonstrates that targeting IDO1 ameliorates dry age-related macular degeneration by suppressing ferroptosis and NLRP3 inflammasome activation in retinal pigment epithelial cells, thereby preserving retinal structure and function in a NaIO₃-induced mouse model.