📄 medicine

Exploring the impact of glycemic control on renal, hepatic, and lipid biomarkers in diabetic patients: a retrospective laboratory analysis from 2019 to 2022

This retrospective laboratory analysis from 2019 to 2022 demonstrates that poor glycemic control in diabetic patients is significantly associated with concurrent abnormalities in renal, hepatic, and lipid biomarkers, underscoring the clinical necessity of interpreting HbA1c alongside these organ-specific markers to better detect complications and guide personalized care.

Muhammad Rehan Uppal, Rizwan Uppal, Umar Saeed, Muhammad Saad Uppal, Aftab Ahmad Khan, Zahra Zahid Piracha2026-07-08
📄 medicine

Evaluation of Anti‑Diarrheal Activity of Crude Methanol Root Extract and Solvent Fractions of Ficus thonningii (Moraceae) Using Swiss Albino Mice

This study validates the ethnomedicinal use of *Ficus thonningii* roots for treating diarrhea by demonstrating that its crude methanol extract and solvent fractions, particularly the aqueous fraction, exhibit significant dose-dependent anti-diarrheal activity in Swiss albino mice through multiple mechanisms.

Sisay Tarekegn Gebyaw, Muluken Adela Alemu, Mestayet Geta Mengistie, Assefa Belay Asrie2026-07-08
📄 medicine

Approved Mental Health Professionals’ (AMHPs) lived experience of the roleand factors that could support improved recruitment, retention, and wellbeing: a qualitative study

This qualitative study of 23 Approved Mental Health Professionals (AMHPs) in Wales utilizes the Job Demands-Resources framework to identify systemic challenges affecting recruitment, retention, and wellbeing, ultimately proposing five key areas for improvement including shift design, supervision, interagency collaboration, infrastructure, and professional development.

Francesca Mazzaschi, Abubakar Sha'aban, Rebecca Roberts, Muawiyah Sheraz, Anthony Cope, Adrian Edwards, Natalie Joseph-W (…)2026-07-08
📄 medicine

Workplace Bullying Among Nursing Students: Prevalence, Consequences, and the Bullying-to-Attrition Cascade Framework

This cross-sectional study of 102 nursing students in Kenyan hospitals reveals a 79.4% prevalence of workplace bullying primarily perpetrated by qualified staff, which significantly harms mental health and learning while prompting the authors to propose the Bullying-to-Attrition Cascade Framework (BACF) as a theoretical model for intervention.

Winfridah Wangui Njung'e, Stanley Bwire2026-07-08
📄 medicine

Chalcone Derivative B8HA as A Novel Histone Deacetylase and Tubulin Dual-targeting Inhibitors, Inhibits Triple-Negative Breast Cancer Cells Proliferation

The study demonstrates that the novel chalcone derivative B8HA acts as a potent dual-targeting inhibitor of histone deacetylase and tubulin, effectively suppressing triple-negative breast cancer cell proliferation, inducing apoptosis, and inhibiting metastasis and angiogenesis both in vitro and in vivo.

Yi Su*, Ling Li*, kangkang li, qiuling zheng, shulei qi, yi xie, Xuehong Chen, Yong Fan2026-07-08
📄 medicine

Dramatic Improvement Followed by Rapid Deterioration after Glucocorticoid Pulse Therapy in a Case of Sporadic Creutzfeldt-Jakob Disease with Hashimoto's Encephalopathy Features: A Case Report

This case report describes a patient with sporadic Creutzfeldt-Jakob disease (CJD) who initially presented with Hashimoto's encephalopathy features and showed dramatic but transient improvement following glucocorticoid pulse therapy before rapid deterioration, ultimately confirming the CJD diagnosis through positive 14-3-3 protein and RT-QuIC assays.

Tianchen Wu, Yan Liang, Zhengzheng Wu, Jinbin Chen, Zhennian Zhang, Hui Yang2026-07-08
📄 medicine

Community-based malaria mass drug administration in a moderate transmission setting in Ghana: Pilot randomise control trial

This pilot cluster-randomized trial in rural Ghana demonstrates that nine rounds of community-based mass drug administration with artemether–lumefantrine significantly reduced malaria parasite prevalence by 94% and markedly improved anaemia outcomes, particularly among children under 15 years.

Ndong Ignatius Cheng, Chuo Ennestine Chu, Xue Wu, Ndong Henry Ndang, Brandon Nji Amambua-Ngwa, Nana Yaw Peprah, Keziah M (…)2026-07-08
📄 medicine

The Effect of Mindfulness-Based Stress Reduction Training Given to Young Girls Experiencing Fear of Childbirth on Fear of Childbirth, Coping Strategies with Stress, and State Anxiety Levels

This study demonstrates that a six-session Mindfulness-Based Stress Reduction (MBSR) training program significantly reduces fear of childbirth and state anxiety while improving stress coping strategies among young girls compared to a control group.

HACER UNVER KOCA, FADİME BİÇER ŞAHİN, ZEYNEP UNVER, LALE UNVER AYDIN, FUNDA KAVAK BUDAK2026-07-08