4376 papers
This phenomenological study analyzes social media narratives from Filipino Parkinson's disease patients and caregivers to reveal a journey defined by severe economic hardship, diagnostic delays, and geographic disparities, highlighting the urgent need for improved medication access, multidisciplinary care, and government support in the Philippines.
This retrospective CBCT-based cohort study demonstrates that while impacted third molar extraction alone effectively halts external root resorption and preserves pulp sensibility in affected second molars, adjunctive guided bone regeneration significantly enhances distal alveolar bone regeneration compared to extraction alone.
This retrospective study demonstrates that the free fatty acid-to-apolipoprotein A1 (FFA/ApoA1) ratio is a significant independent predictor of overall survival specifically in nonobese patients with colon cancer, exhibiting superior prognostic value in this subgroup compared to obese patients or those with rectal cancer.
This study reveals a spatial dissociation in Parkinson's disease where subcortical microstructural alterations are strongly linked to presynaptic dopaminergic terminal loss, while cortical changes exhibit consistent, neuroinflammation-related associations with dopaminergic markers.
The orally active apelin receptor agonist CMF-019 crosses the blood-brain barrier to restore microglial metabolism, enhance amyloid-β clearance, and improve cognitive functions in Alzheimer's disease mouse models.
This study validates the Brazilian Portuguese version of the SOS-scale as a reliable and highly accurate tool for detecting iatrogenic withdrawal syndrome in critically ill children, demonstrating strong correlation with the WAT-1 and establishing an optimal diagnostic cut-off score of ≥ 4.
In a retrospective multicenter study of anticoagulated patients hospitalized with upper gastrointestinal bleeding, the specific class of anticoagulant did not predict in-hospital mortality or other clinical outcomes, whereas admission serum creatinine was identified as an independent predictor of death.
This case report details the successful total resection of an extremely rare craniovertebral junction chondromyxoid fibroma with myogenic differentiation and mutant-pattern P53 expression using a precision multimodal surgical approach, highlighting the tumor's potential for malignant transformation and the critical need for rigorous surveillance and targeted therapeutic strategies.
This retrospective cohort study of 265 patients undergoing one-hole split endoscopy for lumbar disc herniation demonstrates that preoperative sarcopenia and fatty infiltration in paraspinal and gluteal muscles are independent predictors of chronic postoperative low back pain and inferior long-term functional outcomes, suggesting that muscle-sparing surgical techniques alone cannot fully compensate for pre-existing biomechanical impairments.
This study of over 111,000 participants across Chinese, English, and European cohorts found that a higher metabolic-vascular burden is modestly associated with an increased risk of subsequent Parkinson's disease, though the strength of this association varies significantly by population context.