14450 papers
A study of 30 parents found that a majority would accept participating in a first-in-human trial of artificial womb technology for 23-week gestational infants, driven by hope for better outcomes, though their willingness depends on transparent communication regarding risks and trial safeguards.
This study reveals that while baseline host inflammatory fitness predicts early treatment success in relapsed/refractory large B-cell lymphoma, the distinct long-term efficacy of axi-cel versus tisa-cel is driven by qualitative immune remodeling, where axi-cel's unique ability to induce balanced CAR-T expansion and bystander activation yields more durable responses despite lower peripheral cell counts.
This prospective cohort study of Swedish twins reveals that an ischemic heart disease diagnosis is associated with a reduced probability of sustainable working life, a relationship partially explained by shared genetic and early-life environmental factors rather than sex or common mental disorders.
This retrospective study demonstrates that gonadotropin-releasing hormone agonist treatment effectively suppresses puberty and attenuates skeletal maturation in children with Lennox–Gastaut syndrome and central precocious puberty, while also suggesting that underlying neurological etiologies, such as hypoxic–ischemic encephalopathy, may influence the severity of bone age advancement and treatment response.
This retrospective qualitative study in eastern Uganda identifies that adverse pregnancy outcomes stem from fragmented care pathways, systemic health system weaknesses (including inadequate staffing, supplies, and referrals), and socio-cultural barriers, underscoring the urgent need for integrated interventions that strengthen clinical practices, referral systems, and community health literacy.
This retrospective study of Finnish medico-legal deaths from 2016 to 2024 reveals that while detections of ADHD medications in post-mortem cases have risen in parallel with prescription rates, fatalities directly attributed to these drugs remain rare, with the deceased predominantly representing a high-risk subgroup characterized by significant substance-use comorbidity and unnatural causes of death.
This 12-month longitudinal study using wearable IMU sensors reveals that spatiotemporal gait parameters and trunk kinematics follow distinct recovery trajectories following simultaneous bilateral total hip arthroplasty, with temporal parameters normalizing by six months while spatial parameters and trunk sway continue to improve or remain impaired compared to healthy controls at one year.
This single-center retrospective case-control study identifies serum ferritin, serum amyloid A, and D-dimer as significant predictive biomarkers for plastic bronchitis in children with severe Human bocavirus 1 monoinfectious pneumonia, suggesting their utility in early clinical identification.
This 2025 cross-sectional study of 347 staff at a Beirut university medical center found that while interprofessional collaboration is generally well-perceived, its effectiveness is primarily determined by collaborative leadership, task clarification, and mutual understanding, yet hindered by communication barriers, hierarchical tensions, and insufficient organizational support.
This multicenter retrospective study demonstrates that Qingre Huashi Touzhen Decoction significantly accelerates symptom resolution and reduces chronic arthralgia sequelae in acute-phase Chikungunya fever patients with ShiYu HuaRe Syndrome, a clinical efficacy mechanistically supported by the synergistic regulation of inflammatory pathways by its bioactive components.