📄 Category

medicine

14450 papers

📄 medicine

Clinical Application of a Modified Gastric-Nasopharyngeal Suction Catheter for Continuous Supraglottic Secretion Management in an Older Patient With Silent Aspiration: A Case Report

This case report demonstrates that continuous supraglottic secretion drainage using a modified gastric-nasopharyngeal suction catheter effectively resolved persistent silent aspiration and associated pulmonary infection in a 93-year-old patient with cognitive impairment, offering a feasible adjunctive management strategy for non-ventilated individuals.

Xiaoyu Zhang, Zhenzhen Liu, Zhiwei Nie, Caiping Liu, Huimin He, Ming Yang, Juan Liu2026-10-11
📄 medicine

Macro TSH and the Misdiagnosis of Hypothyroidism: Evidence from a Cross-Sectional Study

This cross-sectional study demonstrates that relying solely on total TSH levels leads to significant overdiagnosis of hypothyroidism due to macro TSH interference, particularly in asymptomatic and pregnant populations, and advocates for macro TSH screening to prevent unnecessary treatment and improve diagnostic accuracy.

Davoud Amirkashani, Mostafa Abdollahi Sarvi, Mostafa Masoumi, Mona Nourbakhash2026-10-11
📄 medicine

Turnaround time in diagnostics, analysing delays and strategic improvements in a tertiary care hospital

This study evaluates turnaround time delays in a New Delhi tertiary care hospital's biochemistry and haematology laboratories, revealing that while the analytical phase constitutes the largest time proportion, significant delays stem from pre- and post-analytical factors such as administrative bottlenecks, specimen transportation, and HIS inefficiencies, necessitating targeted workflow and staffing improvements.

Danish Ahmad, Saumya Sajiv Kumar Sharma, Manish Sabharwal2026-10-11
📄 medicine

An EEG-informed fNIRS framework uncovers stage-associated cortical dynamics during unassisted upper-limb movement after stroke

This study demonstrates that an EEG-informed multimodal framework combining FBCSP and GLM effectively mitigates hemodynamic artifacts during ecological upper-limb movements in stroke patients, successfully revealing distinct, stage-associated patterns of cortical reorganization across Brunnstrom recovery stages that conventional methods fail to capture.

Mingyang Wang, Xiaojuan Chen, Zhenlan Li, Yulin Gong2026-10-11
📄 medicine

Effects of Frailty Status on Hospitalization Risk and Healthcare Costs among Patients Undergoing Maintenance Haemodialysis: A Retrospective Cohort Study

This retrospective cohort study of 738 maintenance haemodialysis patients in East China demonstrates that pre-frailty and frailty are independently associated with significantly increased frequencies and costs of all-cause hospitalizations, revealing a clear dose-response relationship that underscores the need for early frailty detection to reduce healthcare burdens.

JINPING YING, YAHUI ZHOU, YINV WU, LINGLIN CHEN, HUIMIN BAO, YUJIAO ZHANG, QI GUO, GENLIAN CAI, JIEHUI FENG2026-10-11
📄 medicine

Preoperative Chemoradiotherapy Versus Upfront Surgery for Early-Onset Clinical Stage II–III Rectal Cancer: A Multicenter Asian Registry Study

This multicenter Asian registry study found that preoperative chemoradiotherapy did not significantly improve disease-free or overall survival compared to upfront surgery in patients with early-onset clinical stage II–III rectal cancer who underwent surgical resection.

Taketo Sasaki, Akira Ouchi, Yasuyuki Takamizawa, Fumio Tsukamoto, Hiroshi Nagata, Shunsuke Tsukamoto, Yukihide Kanemitsu (…)2026-10-11
📄 medicine

Failed proximal femur fracture fixation with Broken Cephalomedullary Nails: Outcomes of Conversion Total Hip Arthroplasty Using a Monoblock Tapered Fluted Revision Stem

This study demonstrates that conversion total hip arthroplasty using a cementless monoblock tapered fluted revision stem provides reliable femoral fixation and acceptable functional outcomes for patients with failed proximal femur fracture fixation due to broken cephalomedullary nails, although postoperative functional results are significantly influenced by preoperative ASA grade.

Davide Stimolo, Fernando Nahuel Martin Cocilova, Filippo Castrogiovanni, Filippo Leggieri, Roberto Civinini, Matteo Inno (…)2026-10-11
📄 medicine

Association of Dietary Polyamines with the Prevalence of Gestational Diabetes Mellitus: A Cross-Sectional Study in Chinese Pregnant Women

This cross-sectional study of 1,007 Chinese pregnant women found that higher dietary intakes of spermidine and putrescine, but not spermine, were significantly associated with an increased prevalence of gestational diabetes mellitus.

Tianru Mei, Yiting Song, Rui Zhang, Xinyu Deng, Yan Wang, Min Song, Dan Wang, Xuchen Yang, Yifei Shao, Sihan Jing, Renna (…)2026-10-11
📄 medicine

Whole-Cardiac-Cycle ECG Dynamics in Critical Illness: The Spatial QRS- T Angle as a Prognostic Marker, an Early-Warning Signal for Arrhythmia and Myocardial Injury, and an In-Vivo Pharmacodynamic Readout

This study demonstrates that in critically ill patients, the spatial QRS-T angle derived from the first ECG is the strongest predictor of 28-day mortality, while new-onset repolarization abnormalities serve as early warning signals for arrhythmias and myocardial injury, establishing whole-cycle ECG dynamics as a comprehensive, actionable monitoring tool for prognosis and pharmacodynamic assessment in the ICU.

Ye Hui, Zhang Qian, Chen Song, Li Peiwu, Wan Jian, Yilong Hao2026-10-11