📄 Category

medicine

4603 papers

📄 medicine

Personalized 3D printing-assisted preoperative simulation surgery improves surgery outcomes and function recovery for complex tibial plateau fractures: a retrospective cohort study

This retrospective cohort study demonstrates that personalized 3D printing-assisted preoperative simulation significantly improves surgical efficiency, reduces intraoperative trauma and complications, and enhances long-term functional recovery for patients with complex tibial plateau fractures compared to conventional surgery.

Lugen Li, Chenpeng Zhang, Jinrong Liang, Xiao Wei, Zhengbo Hu2026-07-08
📄 medicine

Metformin for fatigue and cognitive dysfunction associated with postCOVID-19 condition and other suspected mitochondrial dysfunction: a case series

This case series reports that metformin rapidly improved severe fatigue and cognitive dysfunction in three women with post-COVID-19 condition or aromatase inhibitor-related symptoms, with symptom recurrence upon discontinuation and improvement upon re-initiation, suggesting a potential role for metformin in treating these syndromes linked to suspected mitochondrial dysfunction.

James E. Stahl2026-07-08
📄 medicine

Isatuximab-related uveal effusion in multiple myeloma: expanding the spectrum of anti-CD38 therapy ocular toxicity

This paper reports a case of bilateral acute angle closure caused by uveal effusion following isatuximab infusion in a multiple myeloma patient, highlighting a potentially underrecognized ocular toxicity of this anti-CD38 therapy that resolved with medical management.

Paula García-Valentín, Laura Sánchez Vela, Jaume Rigo Quera, Mercedes Gironella Mesa, Judith Ramirez Guerrero, Alba Jord (…)2026-07-08
📄 medicine

Integrating Vascular, Neurological, and Metabolic Factors into a Validated Nomogram to Predict 90‑day Outcomes after Mechanical Thrombectomy for Acute Ischemic Stroke

This study developed and validated an interpretable nomogram incorporating vascular, neurological, and metabolic factors to effectively predict 90-day functional outcomes in acute ischemic stroke patients undergoing mechanical thrombectomy, demonstrating robust performance comparable to machine learning models while offering enhanced clinical transparency.

Huiqin Huang, Xiaoyan Han, Junning Mo, Junle Zhao, Mingjie Chen, Guanghui Wang, Weikun Zhou, Lian Huang, Youjia Li2026-07-08
📄 medicine

Population Ageing, Non-Communicable Disease Burden, and Financial Implications in Sri Lanka: A Secondary Data Analysis (2012–2024)

This secondary data analysis reveals that Sri Lanka is undergoing rapid demographic ageing with a 70.8% increase in its elderly population from 2012 to 2024, driving a significant rise in non-communicable disease burdens and a sharp increase in out-of-pocket health expenditures to 54.8%, thereby necessitating urgent, district-specific policy interventions to strengthen geriatric care and financial protection.

Dineshan Ranasinghe, Dulanjali Ratnayake, Sumal Nandasena2026-07-08
📄 medicine

The Effects of Sugammadex in Experimental Organophosphate Toxicity: comparison with atropine and pralidoxime treatment

This experimental study on rabbits demonstrates that administering sugammadex, particularly in combination with standard atropine and pralidoxime therapy, significantly improves erythrocyte and tissue acetylcholinesterase activity compared to standard treatment alone in acute organophosphate toxicity.

Ayşegül Bayır, Hasan Kara, Murat Akıncı, Sedat Abuşoğlu, Ceyhan Uğurlu, Fatih İkiz2026-07-08
📄 medicine

Computer Vision Syndrome: Prevalence and Associated Risk Factors Among Undergraduate Students in Mai-Nefhi College of Science and Engineering, Eritrea

This cross-sectional study of 352 undergraduate students at Mai-Nefhi College of Science and Engineering in Eritrea reveals a 65.3% prevalence of Computer Vision Syndrome, identifying female gender, glare exposure, refractive errors, and higher academic year levels as significant risk factors.

Hana Ghebreberhan, Feven Habtom, Furtuna Melake, Lidya Seltene, Rosa Semere, Samrawit Ablel, Afeworki Weldezghi, Aman Di (…)2026-07-08
📄 medicine

Early prediction of 30-day mortality in critically ill patients with interstitial lung disease and acute hypoxemic respiratory failure: development and external validation of a clinically interpretable model

This study developed and externally validated a clinically interpretable, parsimonious model using six early non-treatment variables to predict 30-day mortality in critically ill patients with interstitial lung disease and acute hypoxemic respiratory failure, finding that while adding treatment-related variables improved discrimination, the baseline model offered superior overall predictive accuracy and remains the preferred tool for early risk stratification despite moderate external performance.

Lan Lin¹², Shuqi Lin⁵, Mhrayi Abulimit⁵, Lixuan Zhou³⁴, Zihang Wei⁵, Xiaoqin Li³⁴, Xiaoqin Li2026-07-08
📄 medicine

Prevalence and Associated Factors of Physical and Sexual Violence against People Who Inject Drugs in Iran :A Nationwide Survey in 2023

A 2023 nationwide survey of 2,361 people who inject drugs in Iran reveals alarmingly high rates of physical (27.0%) and sexual (15.1%) violence, which are significantly associated with structural vulnerabilities like homelessness and low income, as well as specific risk factors such as mental disorders and female gender.

Kamiar Izadpanah, Seyed Aria Nejadghaderi, Masoud Rezaei, Soheil Mehmandoost, Fatemeh Tavakoli, Maliheh Sadat Bazrafshan (…)2026-07-08