📄 Category

medicine

14674 papers

📄 medicine

Associations of Depression and Sarcopenia with ADL Disability and All-Cause Mortality in Chinese Older Adults: A 7-Year Prospective Cohort Study

This 7-year prospective cohort study of 4,161 Chinese older adults reveals that while depression independently predicts activities of daily living (ADL) disability and low grip strength predicts mortality, the co-occurrence of depression and sarcopenia confers the highest additive risk for both adverse outcomes, particularly among adults aged 60–69.

Xin Liao, Bingyao Liu, Song Yu, Bin Guo, Ke Yu2026-10-11
📄 medicine

Association between prophylactic pancreatic stent length and post-ERCP pancreatitis: a propensity score–matched cohort study

This propensity score–matched cohort study suggests that using longer prophylactic pancreatic stents (6–9 cm) is associated with a significantly lower incidence of post-ERCP pancreatitis compared to 5-cm stents in high-risk patients, though the findings are considered hypothesis-generating due to the retrospective, non-randomized design.

Menghan Wang, Yijun Chen, Yan Zhao, Wenhai Wang2026-10-11
📄 medicine

Clinical Features and Prognostic Factors of Bone Metastasis in Esophageal Squamous Cell Carcinoma: a retrospective cohort study

This retrospective cohort study of 334 patients with esophageal squamous cell carcinoma and bone metastasis identifies performance status, the number of extrabony metastases, concurrent hepatic metastasis, and the application of local therapy for bone lesions as independent prognostic factors for survival, highlighting the particularly poor prognosis associated with liver involvement.

Yu Yang, Ruojun Xu, Xiaozhi Tang2026-10-11
📄 medicine

Polycystic kidney disease in pregnancy: A retrospective study on obstetric and neonatal outcomes

This retrospective population-based study utilizing the HCUP-NIS database found that pregnant women with polycystic kidney disease face significantly increased risks of hypertensive disorders, preterm delivery, and small-for-gestational-age infants compared to those without the condition, highlighting the need for tailored monitoring and patient education.

Zoé Frayret, Ahmad Badeghiesh, Haitham Baghlaf, Michael H. Dahan2026-10-11
📄 medicine

Integrated Metabolomics and Second-Tier Genomic Analysis for Expanded Newborn Screening of Inborn Errors of Metabolism: Protocol for a Multicentric Prospective Cohort Study in India

This protocol outlines a multicenter prospective cohort study in India designed to evaluate an integrated newborn screening approach combining LC–MS/MS metabolomics with second-tier targeted NGS to improve the early detection, diagnostic accuracy, and clinical management of inborn errors of metabolism.

Sunil Kumar Polipalli, Neerja Gupta, Seema Kapoor, Madhulika Kabra, Amit Kumar Gupta, Hem lata, Ashish Jain, Ramesh Agga (…)2026-10-11
📄 medicine

Taeniasis-cysticercosis has no borders in Sub-Saharan Africa: pig traders' knowledge, attitudes, and practices regarding Taenia solium in the cross-border pig food chain between Zambia and the Democratic Republic of Congo.

This study reveals that cross-border pig traders between Zambia and the Democratic Republic of Congo possess limited knowledge of *Taenia solium* and engage in risky practices that allow infected pigs to reach consumers, highlighting the urgent need for coordinated "One Health" strategies to control the parasite in Sub-Saharan Africa.

Alain Tshiasuma Kedi, Inge Van Damme, Sarah Gabriël2026-10-11
📄 medicine

Long-Term Outcomes of Maintenance Peritoneal Dialysis Initiated During Infancy: A Temporally Aligned Comparative Study

This retrospective study reveals that infants initiating maintenance peritoneal dialysis face significantly higher mortality and complication rates compared to temporally aligned older children, yet more than half successfully undergo kidney transplantation, supporting PD as a viable bridge to transplant despite the high risks.

Ruveyda Gulmez, Nur Canpolat, Esra Karabag Yilmaz, Seha Saygılı, Ayse Agbas, Gulseren Pehlıvan, Salim Caliskan, Lale Sev (…)2026-10-11
📄 medicine

Impact of donor kidney weight and recipient body mass index on long-term renal function decline following living donor kidney transplantation

This multicenter retrospective study of 536 living donor kidney transplant recipients demonstrates that the combination of low donor kidney weight and high recipient body mass index is an independent predictor of long-term graft function decline, underscoring the critical importance of nephron mass matching in donor selection and recipient risk stratification.

Kenta Ishikawa, Ayato Ito, Ryohei Yamamoto, Mitsuru Saito, Ryuichiro Sagehashi, Kengo Furihata, Chika Kajiwara, Mizuki M (…)2026-10-11
📄 medicine

Symptom Network Analysis of Insomnia, Depression, and Anxiety Among Incarcerated Men in China: Implications for Correctional Mental Health Assessment

This study utilized network analysis on 584 incarcerated men in China to identify "awakenings during night" and "daytime functioning capacity" as core insomnia symptoms, while pinpointing "restlessness," "sleep," and "sad mood" as key bridge symptoms, thereby offering targeted insights for mental health screening and intervention strategies within correctional facilities.

Tong Chen, Shuqing Wang, Qingyin Xiao, Yuwei Lu, Meng-Cheng Wang2026-10-11