4603 papers
This longitudinal qualitative study of 28 breast cancer survivors reveals that fear of cancer recurrence is a dynamic, highly individualized experience triggered by diverse situational factors and managed through a wide array of coping strategies, underscoring the need for personalized psycho-oncological interventions.
This case report describes a patient who survived severe bupivacaine-induced myocardial depression requiring VA-ECMO support, highlighting a unique clinical trajectory characterized by a delayed functional nadir at 24 hours followed by a reversible recovery that was effectively monitored via serial echocardiography to guide weaning.
This phenomenological study of Turkish cancer survivors reveals that while they face persistent physical and psychological challenges post-treatment, they also employ diverse coping strategies to achieve personal growth, highlighting the need for culturally sensitive, multidisciplinary survivorship care.
This randomized controlled trial demonstrates that anterior reversed PHILOS plating is a safe and effective alternative to conventional posterior double plating for extra-articular distal humeral shaft fractures, offering comparable functional outcomes and union rates while significantly reducing operative time, surgical exposure, and the risk of nerve injury.
This study presents an integrated single-cell transcriptomic pipeline that identifies ZNF740/BRD3, Cathepsin S, and DNMT1 as novel, blood-accessible therapeutic targets for treating chronic active rim smoldering multiple sclerosis through BET bromodomain inhibition, protease targeting, and epigenetic reprogramming, respectively.
This population-based study in Hubei, China, found that the six-month virological failure rate among treatment-naïve people living with HIV was 6.8%, with female sex, higher baseline CD4 counts, and INSTI-based regimens identified as protective factors, while high baseline viral load and drug use-associated infection were significant risk factors.
This retrospective study of seven cases highlights that gestational diabetic ketoacidosis, often triggered by dexamethasone or pancreatitis, carries high fetal mortality risks and is frequently followed by persistent long-term metabolic complications, underscoring the necessity for prolonged multidisciplinary surveillance and strict glycemic management.
This retrospective case series of four patients demonstrates that the Reper artificial iris prosthesis Model C, implanted via a three-point scleral fixation technique, is a safe and effective treatment for traumatic aniridia and aphakia, yielding significant improvements in visual function, symptom relief, and cosmetic satisfaction despite rare long-term complications.
This protocol outlines a single-center pilot randomized controlled trial in Canada designed to assess the feasibility of a larger study and explore the biological effects of a liberal versus restrictive red blood cell transfusion strategy on bleeding-related biomarkers in patients with acute leukemia undergoing induction chemotherapy.
This study demonstrates that homocysteine metabolic dysregulation drives oral submucous fibrosis through a p53-SMAD3 signaling pathway and that this pathological process can be effectively reversed by localized 5-methyltetrahydrofolate supplementation.