4603 papers
Carrimycin effectively ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by suppressing systemic inflammation, restoring the Th17/Treg immune balance, and reconstructing the gut microbiota composition.
This dual-cohort longitudinal study of 4,157 Chinese undergraduates reveals that dormitory peer effects significantly shape physical fitness trajectories, with dormitory clustering emerging as a stronger predictor of senior-year fitness outcomes than BMI or sex, thereby highlighting the potential of targeted dormitory interventions during the freshman-sophomore transition to combat fitness decline.
This cross-sectional study in southern Kazakhstan developed and preliminarily validated the PQoL-34 questionnaire, demonstrating its high content validity, strong internal consistency, and convergent validity as a comprehensive tool for assessing quality of life during pregnancy and family readiness for childbirth.
Using 2024 Nigeria Demographic and Health Survey data, this study found that while socioeconomic and informational factors significantly influence skilled birth attendance utilization among Nigerian women, household Water, Sanitation, and Hygiene (WASH) conditions were not significantly associated with its use after adjusting for these confounders.
This prospective cohort study in Western Kenya demonstrates that despite universal antiretroviral therapy use, maternal HIV infection remains independently associated with a significantly increased risk of low birth weight and preterm birth, a finding robustly confirmed through weighted propensity score matching and inverse probability weighting methods.
Using 2024 Nigeria Demographic and Health Survey data, this study reveals that despite the North-West having higher fertility and lower contraceptive use, the demand for modern family planning is significantly higher in the South-West, with education and the number of living children serving as common predictors across both regions while other factors vary by location.
This case report details the complex clinical course of a very preterm infant who developed *Candida albicans* sepsis and meningitis, leading to severe complications including intraventricular hemorrhage, hydrocephalus, and congenital cataract, thereby underscoring the critical need for early diagnosis and multidisciplinary management in such high-risk neonates.
This study highlights that pharyngeal liposarcomas are frequently misdiagnosed as benign lesions due to their bland and heterogeneous histology, underscoring the critical necessity of MDM2 amplification testing for accurate early diagnosis.
Based on a nationwide Chinese cohort study, sarcopenia and low handgrip strength are significant predictors of both prevalent and incident gastrointestinal diseases, whereas muscle mass alone does not predict future risk, highlighting the superior value of assessing muscle function over quantity in this context.
This multicenter study in China developed and psychometrically validated the 38-item CaregiverCPP scale, a reliable and valid disease-specific instrument designed to assess the unique experiences, burdens, and decision-making drivers of caregivers managing children with central precocious puberty.