14817 papers
This case report highlights the importance of considering methemoglobinemia in children with persistent low pulse oximetry readings despite normal clinical status and cardiopulmonary workups, emphasizing that the discrepancy between low saturation and preserved arterial oxygen tension serves as a critical diagnostic clue to avoid unnecessary investigations.
This prospective cohort study of 381 women found that cesarean scar niches are highly prevalent (63.8%) and are independently predicted by higher BMI, emergent delivery, and hormonal contraceptive use, with larger defects associated with diabetes and lower fetal head station, yet neither the presence nor severity of the niche correlated with increased short-term postpartum symptoms.
This study of 897 people who use opioids in Baltimore reveals that methadone and buprenorphine treatments are associated with distinct sociodemographic profiles and risk patterns, with methadone users showing higher injection frequency but lower recent overdose rates, while buprenorphine users exhibit lower co-use but higher lifetime overdose histories, suggesting a need for tailored harm reduction strategies for each treatment modality.
This study of a Swedish pediatric cohort demonstrates that whole-genome sequencing identifies pathogenic genetic variants in 16% of patients with coarctation of the aorta, supporting the routine use of genetic testing to uncover underlying disorders even in the absence of overt clinical signs.
This post hoc analysis of the Phase III RENOTORCH trial reveals that lipid-lowering therapy use is significantly associated with improved overall survival specifically in patients with advanced renal cell carcinoma treated with toripalimab plus axitinib, but not in those treated with sunitinib.
This study utilizes National Family Family Health Survey-5 data to demonstrate that relying solely on hypertension prevalence for resource allocation in India is misleading, as absolute burden is concentrated in populous districts with lower prevalence, necessitating a dual-prevalence-and-burden approach for effective district-level targeting.
This cross-sectional study of 75 cross-border exchange nurses between Guangxi and Hong Kong reveals that their psychological resilience is significantly high and independently predicted by older age, greater social support, and better adaptation levels.
This longitudinal study demonstrates that a comprehensive Student Support Program integrating academic and non-academic factors effectively reduces the prevalence of high-need profiles and improves academic performance among medical students over one year.
This nationwide cross-sectional study in South Korea applied a Multilevel Model of Healthcare Professional Well-Being to reveal that resident well-being is significantly heterogeneous across postgraduate years and specialty tracks, with junior residents and those in essential specialties facing more adverse organizational conditions and individual stressors despite similar burnout levels.
This study demonstrates that pilocarpine hydrochloride offers a dual therapeutic benefit for fungal infections by simultaneously inhibiting the growth of various fungal species and attenuating neutrophil-driven inflammation through the induction of apoptosis and suppression of activation, thereby reducing immune-mediated tissue damage.