📄 Category

medicine

4603 papers

📄 medicine

Longitudinal Effects of Cardiometabolic Phenotypes and Socioeconomic Status on Psychological-cognitive comorbidity: Cohort Evidence from China, the United States, and the United Kingdom

This longitudinal study across China, the US, and the UK demonstrates that higher cardiometabolic disease burden, specific disease types like cardiovascular disease, and low socioeconomic status independently increase the risk of psychological-cognitive comorbidity in middle-aged and older adults, highlighting the need for integrated medical and socioeconomic interventions.

Beibei Yang, Dezhi Zhang, Xinyue Chen, Xiaoqing He, Dong Li, Shuai Zhang2026-07-07
📄 medicine

Association Between the Hemoglobin-to-Red Cell Distribution Width Ratio and Risk of Type 2 Diabetic Kidney Disease: A Machine Learning Study

This machine learning study utilizing the MIMIC-IV database demonstrates that the hemoglobin-to-red cell distribution width ratio (HRR) is a superior, nonlinear predictor of type 2 diabetic kidney disease risk compared to hemoglobin or RDW alone, with an optimal risk threshold of 6.9492 identified via the LightGBM algorithm.

Feng li, Yali LI li, Hongsheng Ren, Lujing Meng, Jiefang Zhang Zhang2026-07-07
📄 medicine

Serial Transthoracic Echocardiography for Hemodynamic Monitoring and Early Warning of Hypotension During Elective Cesarean Delivery: A Prospective Observational Study

This prospective observational study demonstrates that serial transthoracic echocardiography can detect significant reductions in stroke volume prior to the onset of clinically apparent hypotension in women undergoing elective cesarean delivery under spinal anesthesia, establishing its potential as an early warning tool for hemodynamic monitoring.

Weiping Liu, Yongde Zhou, Dan Li, Lijie Sun, Xuedong Wang, Ting Fan, Xiangyang Guo, Min Li, Chengmei shi2026-07-07
📄 medicine

The Mayo Score Reflects Disease Extent but Not Premalignant Colorectal Lesions or Extraintestinal Manifestations in Ulcerative Colitis

This study demonstrates that while the Mayo Score effectively reflects disease extent in ulcerative colitis, it fails to predict the presence of premalignant colorectal lesions or extraintestinal manifestations, suggesting it measures current severity rather than long-term complications.

Cüneyt Çağatay, Mehmet Kürşad Keskin, Macit Gülten2026-07-07
📄 medicine

Development of a noninvasive murine model of hyperthermic intraperitoneal chemotherapy (HIPEC) treatment for ovarian cancer

This study presents the first noninvasive murine model of hyperthermic intraperitoneal chemotherapy (HIPEC) for ovarian cancer, demonstrating that external abdominal heating combined with chemotherapy significantly attenuates tumor growth, delays ascites development, and extends survival compared to normothermic treatment, thereby enabling mechanistic studies to optimize HIPEC protocols.

Zahraa Alali, Olivia G. Patterson, Sam Lee Sangmyung, Max P. Horowitz, Danielle Chau, Rashmi Bharti, Jing Hao, Peng Qi (…)2026-07-07
📄 medicine

Early-life multimorbidity and health-related quality of life in adolescence: insights from the Norwegian Mother, Father and Child Cohort Study (MoBa)

This study of over 22,000 Norwegian adolescents reveals that early-life multimorbidity is significantly associated with reduced health-related quality of life, particularly in mental wellbeing, with the negative impact appearing to be primarily additive based on the number of conditions rather than specific comorbidity patterns.

Daniela Bragantini, Laura Hegemann, Johanne Hagen Pedersen, Mezeret M. Bazezew, Christina Dardani, Amy Shakeshaft, Ole A (…)2026-07-07
📄 medicine

Improvement in peripheral airway function after a 12-week exercise intervention in COPD

A 12-week supervised exercise intervention in patients with COPD significantly improved peripheral airway function as measured by impulse oscillometry and enhanced exercise capacity and symptoms, despite showing minimal changes in traditional spirometry and lung volumes.

Anna Cederberg, Hugo Öhrneman, Linda Elowsson, Ellen Tufvesson, Caroline Larsson, Bryan Falcones, Lisa Karlsson, Hamid A (…)2026-07-07
📄 medicine

A nomogram for predicting carotid plaque in elderly patients using the ApoB/ApoA1 ratio: a retrospective cohort study

This retrospective cohort study developed and internally validated a simple nomogram using age, sex, HbA1c, and the ApoB/ApoA1 ratio to effectively predict carotid plaque risk in elderly general practice patients, offering a practical tool for individualized risk stratification and clinical decision-making.

亚鲁 李, 飞飞 曹, 丹丹 杨, 于杰 陈, 勒 徐, 惠民 沈, 费 滕, 潮 董2026-07-07
📄 medicine

Clinical and Pathological Characteristics of Mucinous Adenocarcinoma in Colon Cancer: Comparison with Classic Adenocarcinoma

In a retrospective study of colon cancer patients, mucinous adenocarcinomas were found to be more frequently right-sided and poorly differentiated than classic adenocarcinomas, yet they were not independently associated with deeper tumor invasion or nodal metastasis after adjusting for confounding factors.

Berkan ACAR, Ali MUHTAROĞLU, Tuğrul KESİCİOĞLU, Serdar ACAR, Elif YILMAZ, Yavuz ÇEKİÇ2026-07-07