4603 papers
This retrospective study demonstrates that a higher hemoglobin-to-red blood cell distribution width ratio (HRR) is an independent protective biomarker associated with a reduced risk of central retinal vein occlusion and predicts better visual outcomes following anti-VEGF therapy.
This study demonstrates that protocatechuic aldehyde ameliorates high-fat diet-induced hepatic cholesterol dysregulation in rats by upregulating LDLR, LXRα, and CYP7A1 while downregulating PCSK9, thereby enhancing LDL uptake and bile acid synthesis to reduce lipid accumulation and atherosclerotic risk.
This study of nearly 10,000 Chinese adults over 45 reveals that adverse childhood experiences are significantly associated with depressive symptoms in later life, a relationship that is partially mediated by sleep duration.
This scoping review analyzes 67 studies to map how armed conflict disrupts continuity and coordination of care through five interdependent domains—people, hardware, services, linkages, and governance—thereby identifying systemic leverage points for designing interventions that address root causes rather than isolated consequences in conflict-affected settings.
This study demonstrates that while high-intensity interval training improves glycaemic control in type 2 diabetes patients, divergent fasting lactate responses reveal distinct subgroups with unique serum multi-omics remodelling patterns involving lipid, redox, and immune pathways that are not fully captured by conventional metabolic markers.
In a Swedish middle-aged population, specific immune aging perturbations, particularly an imbalance between naïve and memory CD4+ T cells and a reduction in naïve regulatory T cells, are associated with subclinical coronary atherosclerosis and significant stenosis even before the onset of manifest coronary artery disease.
This case report describes a 37-year-old male who underwent successful microsurgical resection of a cervical vagal schwannoma, during which tumor manipulation triggered three brief episodes of asystole that resolved spontaneously upon cessation of traction, resulting in complete recovery without neurological deficits or pharmacological intervention.
This cross-sectional study of 390 households in conflict-affected Bukavu, DRC, reveals that 80% of families with young children face unacceptable food consumption scores, driven primarily by socioeconomic factors such as employment status, home ownership, and access to credit, thereby highlighting the urgent need for integrated interventions targeting livelihoods and dietary diversity.
This study found that while large language models can support geriatric osteoporosis management, the base ChatGPT 4.5 model outperformed guideline-integrated versions in accuracy and adherence, yet all models exhibited limitations in safety awareness and context-sensitive reasoning, underscoring the continued necessity for expert clinical supervision.
This case report describes the first documented instance of a primary intramuscular ganglioneuroma arising from the psoas muscle in a resource-limited setting, highlighting that despite diagnostic challenges and the absence of immunohistochemistry, definitive diagnosis relies on characteristic histopathology and treatment is successfully achieved through complete surgical excision.