📄 medicine

Senhance-Assisted vs Laparoscopic Pediatric Nissen Fundoplication: A Single-Center Multidisciplinary Comparative Cohort Study from a German Tertiary Center

This single-center comparative cohort study demonstrates that Senhance®-assisted robotic Nissen fundoplication in children is a feasible and safe alternative to conventional laparoscopy, offering comparable surgical and anesthetic outcomes despite longer initial preparation times associated with the learning curve.

Daniel Levin Widmann, Isabel Kiesewetter, Matthias Kurz, Alexandra Schock, Oliver Muensterer, Jan Goedeke2026-07-07
📄 medicine

Neuropsychological and Autonomic Correlates of Chronic Stress in Dermatological Patients: A Comparative Analysis of GABAergic Therapy Regimens

This prospective study of 100 dermatological patients with chronic stress demonstrates that while both systemic and combined systemic-topical GABAergic therapies effectively restore autonomic balance and neuropsychological function, the combined approach may offer a potential advantage in accelerating the normalization of peripheral microcirculation and central neurodynamics.

A. S. Smitneva, I. V. Reverchuk¹, Svetlana Horemans2026-07-07
📄 medicine

Longitudinal plasma metabolomics identifies metabolic signatures of early recurrence and platinum resistance in advanced ovarian cancer

This study utilizes longitudinal plasma NMR metabolomics to identify specific metabolic signatures associated with early recurrence and platinum resistance in advanced ovarian cancer, demonstrating that combining these metabolic biomarkers with clinical data significantly improves prediction accuracy compared to clinical factors alone.

Victoire Bondeville, May-Britt Tessem, Okan Gultekin, Guro F. Giskeødegård, Nina Groes Kofoed, Johan A. Westerhuis, Kais (…)2026-07-07
📄 medicine

Seizure Prophylaxis Versus Epilepsy Prevention After Acquired Brain Injury: A Cross-Sectional ClinicalTrials.gov Registry Analysis, 2000-2026

This cross-sectional analysis of ClinicalTrials.gov records from 2000 to 2026 reveals that the research landscape for seizures following acquired brain injury is fragmented, with significant conflation between acute seizure prophylaxis and long-term epilepsy prevention, necessitating future trials that clearly distinguish these endpoints and improve reporting standards.

Anil Chimakurthy, Viswabhaskar Susarla, Jeet Hemantkumar Chaudhary, Om Desai2026-07-07
📄 medicine

Assessment of the implementation level of Infection Prevention and Control (IPC) for the prevention of antimicrobial resistance in referral hospitals: the case of Kamenge University Teaching Hospital (CHUK), Gitega Regional Hospital, and Natwe Turashoboye Hospital in Karusi, Burundi

This cross-sectional study of three referral hospitals in Burundi reveals that Infection Prevention and Control (IPC) implementation levels are critically insufficient, with global scores ranging from 31 to 42 out of 100 and significant deficits in governance, surveillance, and workforce qualifications.

Prosper Niyonkuru, Niyonsaba Vestine, Fidel BIGIRIMANA2026-07-07
📄 medicine

AI in the clinic: a scoping review of AI and clinical expertise

This scoping review of 58 empirical studies from 2022 onwards indicates that while AI tools significantly enhance physician clinical performance—particularly for novices—current evidence does not support fears of AI-induced deskilling, though further longitudinal research is needed to fully assess long-term impacts on clinical expertise.

Eric Owens, Oliver Buchholz, Yasmine Douar, Vibhuti Thapliyal, Alessandro Blasimme2026-07-07
📄 medicine

Lower Serum Free Triiodothyronine is Independently Associated with Isolated Left Anterior Descending Coronary Slow Flow:A Cross-Sectional Study

This cross-sectional study demonstrates that lower serum free triiodothyronine (FT3) levels are independently associated with and show moderate predictive value for isolated left anterior descending coronary slow flow, suggesting a potential link between thyroid hormone deficiency and coronary microvascular dysfunction.

Jinpeng Zhong, Liwu Dai, Xiaohong Lu, Jianzhong Ruan, Yazhou Li, Yan Lu, Yunqing Chen2026-07-07
📄 medicine

Physician Performance and Inpatient Satisfaction: A Systematic Literature Review

This systematic literature review synthesizes existing research to demonstrate that physician performance—specifically communication skills, professionalism, clinical competence, and patient-centered care—significantly influences inpatient satisfaction through the mediating role of perceived service quality, while also highlighting gaps in studies regarding Islamic hospitals, longitudinal designs, and integrative conceptual frameworks.

Tjatur Prijambodo, Moses Glorino Rumambo Pandin2026-07-07