4608 papers
This paper presents a centralized R Shiny dashboard that integrates Apple Watch sensor data with clinical records from a multi-site HiGHmed study to enable cardiologists to systematically evaluate cardiovascular metrics and detect early signs of clinical worsening in heart failure patients.
This study demonstrates that analyzing unexplained viral encephalitis, meningitis, and acute flaccid paralysis cases using a Bayesian shared-component model can effectively identify hidden West Nile virus transmission hotspots in Spain, offering a potential early-warning system for viral circulation before clinical cases are officially recognized.
This cross-sectional study of 487 Bangladeshi medical students reveals a high prevalence (34.9%) of probable adult ADHD, which is significantly associated with elevated anxiety, depression, stress, and academic underperformance, highlighting an urgent need for routine screening and targeted support within medical curricula.
This Level IIa therapeutic study concludes that while thermal ablation for small resectable colorectal liver metastases offers a significant morbidity advantage over surgical resection, its clinical acceptability depends on lesion selection and the specific definition of local control endpoints, as ablation is associated with higher patient-level local recurrence rates.
This paper reports the first documented case in Mexico of a 32-year-old woman with Gray Platelet Syndrome successfully undergoing a total abdominal hysterectomy through multidisciplinary perioperative management, including platelet transfusion, antifibrinolytic therapy, and balanced general anesthesia, which controlled significant intraoperative bleeding without causing metabolic decompensation.
This case report describes a young obese man whose urinary frequency and polydipsia initially mimicked diabetes mellitus but were ultimately diagnosed as concurrent obesity-related secondary focal segmental glomerulosclerosis and overactive bladder, highlighting the critical need to differentiate adaptive renal pathology from metabolic disease to avoid unnecessary immunosuppression.
This secondary analysis of WHO Global Health Observatory data from 2005 to 2023 reveals that while Nigeria has achieved significant onchocerciasis scale-up and sustained zero human African trypanosomiasis cases, persistent treatment gaps, COVID-19-related programmatic disruptions, and surveillance fragility threaten the country's progress toward 2030 Neglected Tropical Disease elimination targets.
This scoping review finds that East Asian medicine's pattern and constitution diagnoses for chronic musculoskeletal pain exhibit low-to-moderate reproducibility and lack evidence of incremental predictive value over established stratification tools, highlighting an urgent need for standardized diagnostic protocols and rigorous validation against clinical outcomes.
This repeated cross-sectional study of Japanese patients and pharmacists from 2014 to 2023 reveals that while pharmacists consistently maintained high role perception scores, patients' perceptions significantly improved over time—particularly regarding communication and condition assessment—thereby narrowing the gap between the two groups and suggesting that pharmacy policy reforms are increasingly aligning public understanding with professional realities.
This scoping review synthesizes evidence on benzodiazepine dependence in anxiety disorders to advocate for a patient-centered, four-step tapering framework that prioritizes slow, individualized withdrawal supported by cognitive behavioral therapy over abrupt cessation, emphasizing a longitudinal therapeutic relationship to mitigate withdrawal risks and prevent relapse.