📄 Category

medicine

4617 papers

📄 medicine

Gray Platelet Syndrome and Total Abdominal Hysterectomy: Perioperative and Anaesthetic Management of the First Reported Case in Mexico

This paper reports the first documented case in Mexico of a 32-year-old woman with Gray Platelet Syndrome successfully undergoing a total abdominal hysterectomy through multidisciplinary perioperative management, including platelet transfusion, antifibrinolytic therapy, and balanced general anesthesia, which controlled significant intraoperative bleeding without causing metabolic decompensation.

Martha Rocio Duran-Badillo, Mirna Magali Delgado-Carlo2026-07-07
📄 medicine

Urinary Frequency and Polydipsia Mimicking Diabetes Mellitus: Obesity-Related Secondary Focal Segmental Glomerulosclerosis with Concurrent Overactive Bladder — A Case Report

This case report describes a young obese man whose urinary frequency and polydipsia initially mimicked diabetes mellitus but were ultimately diagnosed as concurrent obesity-related secondary focal segmental glomerulosclerosis and overactive bladder, highlighting the critical need to differentiate adaptive renal pathology from metabolic disease to avoid unnecessary immunosuppression.

Muhammad Saad Bin Arshad Arain, Farah Anum Jameel, Zahra Ali Haque, Haider Imran, Dania Hussain, Anas Nasir2026-07-07
📄 medicine

Longitudinal Trends and Programmatic Gaps in Selected Neglected Tropical Disease Control Indicators in Nigeria, 2005–2023: A WHO Global Health Observatory Secondary Data Analysis

This secondary analysis of WHO Global Health Observatory data from 2005 to 2023 reveals that while Nigeria has achieved significant onchocerciasis scale-up and sustained zero human African trypanosomiasis cases, persistent treatment gaps, COVID-19-related programmatic disruptions, and surveillance fragility threaten the country's progress toward 2030 Neglected Tropical Disease elimination targets.

Fabunmi Abiola David, Fayomi Blessing Esther, Babatunde Taiye Olayinka2026-07-07
📄 medicine

Reproducibility and incremental predictive value of pattern and constitution diagnosis in chronic musculoskeletal pain: a scoping review

This scoping review finds that East Asian medicine's pattern and constitution diagnoses for chronic musculoskeletal pain exhibit low-to-moderate reproducibility and lack evidence of incremental predictive value over established stratification tools, highlighting an urgent need for standardized diagnostic protocols and rigorous validation against clinical outcomes.

Byungwoong Yoo2026-07-07
📄 medicine

Changes in Pharmacists’ Perceptions of their Roles During Pharmacy Policy Reforms: A Comparative Repeated-Cross-Sectional Study of Patients and Pharmacists

This repeated cross-sectional study of Japanese patients and pharmacists from 2014 to 2023 reveals that while pharmacists consistently maintained high role perception scores, patients' perceptions significantly improved over time—particularly regarding communication and condition assessment—thereby narrowing the gap between the two groups and suggesting that pharmacy policy reforms are increasingly aligning public understanding with professional realities.

Naohito Takahashi, Akira Yoshida, Norimitsu Horii, Shigeru Ohshima, Junya Mikata, Daisuke Kobayashi, Shinji Oshima2026-07-07
📄 medicine

Benzodiazepine Use Disorder and Withdrawal Challenges in Anxiety Disorders: An Evidence-Informed Scoping Review and Patient-Centered Four-Step Tapering Framework

This scoping review synthesizes evidence on benzodiazepine dependence in anxiety disorders to advocate for a patient-centered, four-step tapering framework that prioritizes slow, individualized withdrawal supported by cognitive behavioral therapy over abrupt cessation, emphasizing a longitudinal therapeutic relationship to mitigate withdrawal risks and prevent relapse.

Pooya Zeinali, Negar Zeinali2026-07-07
📄 medicine

Predictive models for stillbirth and neonatal death: A global scoping review of model performance, validation, transportability and implications for sub-Saharan Africa

This global scoping review of 93 predictive models for stillbirth and neonatal death reveals that while 28% of studies focus on sub-Saharan Africa, most models lack rigorous external validation, calibration assessment, and evidence of clinical utility, highlighting an urgent need for standardized, multi-site validation in independent African cohorts to ensure effective deployment.

Tanida Chaweewong, Audencio Victor, Phillip Wanduru, Miriam Bourke, Peter Waiswa, Hannah Blencowe, Eric O. Ohuma, Joseph (…)2026-07-07
📄 medicine

Efficacy, Safety, and Certainty of Evidence for Systemic Antineoplastic Therapies in Treatment-resistant Adult Malignancies: A Systematic Review, Exploratory Meta-analysis, and Grade Assessment

This systematic review and exploratory meta-analysis of 18 randomized clinical trials (2021–2026) concludes that while selected systemic antineoplastic therapies offer clinically meaningful survival and response benefits for adults with treatment-resistant malignancies, high-certainty evidence is concentrated in specific therapeutic contexts and pooled estimates must be interpreted cautiously due to substantial heterogeneity.

Mayky Sousa Rodrigues, Luid Alberto Silva, Carlos Eduardo de Moura Silva2026-07-07
📄 medicine

Effect of Olive Oil Back Massage on Selected Fetomaternal Parameters and Maternal Satisfaction Among Primigravid Women During the First Stage of Labour: A Quasi-Experimental Study

This quasi-experimental study demonstrates that olive oil back massage significantly improves uterine contraction characteristics and yields high maternal satisfaction among primigravid women during the first stage of labour, while maintaining stable fetal and maternal physiological parameters.

Mekala Moorthy2026-07-07