📄 medicine

Divergent fasting lactate responses are associated with serum multi-omics remodelling after 14-week high-intensity interval training in type 2 diabetes

This study demonstrates that while high-intensity interval training improves glycaemic control in type 2 diabetes patients, divergent fasting lactate responses reveal distinct subgroups with unique serum multi-omics remodelling patterns involving lipid, redox, and immune pathways that are not fully captured by conventional metabolic markers.

Jiuxiang Gao, Yuchen Wang, Hui Zuo, Xiaohui Liu, Tao Zhang, Ngai Choi, Chuanzhi Wang, Tianxiao Guo, Xinfei Wen, Weiliang (…)2026-07-07
📄 medicine

Immune aging is associated with subclinical coronary atherosclerosis in a Swedish middle-aged population: A subcohort of the Swedish CArdioPulmonary bioImage Study

In a Swedish middle-aged population, specific immune aging perturbations, particularly an imbalance between naïve and memory CD4+ T cells and a reduction in naïve regulatory T cells, are associated with subclinical coronary atherosclerosis and significant stenosis even before the onset of manifest coronary artery disease.

Rosanna W. S. Chung, Maike Schneider, Anna K. Lundberg, Lena Jonasson2026-07-07
📄 medicine

Recurrent Intraoperative Asystole Induced by Tumor Manipulation in a Cervical Vagal Schwannoma: A Case Report

This case report describes a 37-year-old male who underwent successful microsurgical resection of a cervical vagal schwannoma, during which tumor manipulation triggered three brief episodes of asystole that resolved spontaneously upon cessation of traction, resulting in complete recovery without neurological deficits or pharmacological intervention.

Changqing Li, Erqing Chai, Ke Shuai, Jianglian Chen2026-07-07
📄 medicine

Assessing Household Food security in a conflict-affected urban setting: A cross-sectional study of food consumption scores among households with children aged 6-59 months in Bukavu, Eastern Democratic Republic of the Congo

This cross-sectional study of 390 households in conflict-affected Bukavu, DRC, reveals that 80% of families with young children face unacceptable food consumption scores, driven primarily by socioeconomic factors such as employment status, home ownership, and access to credit, thereby highlighting the urgent need for integrated interventions targeting livelihoods and dietary diversity.

Jean-Paul Ntakobajira Karani, Basimine Lulemire Bienfait, Tristan Asifiwe Mulumeorhwa, Jean-Claude Nkurunziza, Justin Om (…)2026-07-07
📄 medicine

Blinded Expert Evaluation of Large Language Models for Osteoporosis Case Management in Older Adults: Impact of Direct Guideline Integration

This study found that while large language models can support geriatric osteoporosis management, the base ChatGPT 4.5 model outperformed guideline-integrated versions in accuracy and adherence, yet all models exhibited limitations in safety awareness and context-sensitive reasoning, underscoring the continued necessity for expert clinical supervision.

Gokalp Kurthan AVLAGI, Seyda BILGIN, Duygu OZATA, Kubra CINGAR ALPAY, Tugba KANDEMIR, Tugce EMIROGLU GEDIK, Denız SUNA E (…)2026-07-07
📄 medicine

Primary Intramuscular Ganglioneuroma of the Psoas Muscle in a Resource- Limited Setting: A Case Report

This case report describes the first documented instance of a primary intramuscular ganglioneuroma arising from the psoas muscle in a resource-limited setting, highlighting that despite diagnostic challenges and the absence of immunohistochemistry, definitive diagnosis relies on characteristic histopathology and treatment is successfully achieved through complete surgical excision.

Mikyas Befekadu Nigusse, Darrick Lensamo Yeta, Ermias Tadesse Tilahun, Taye Jemberu Robele, Andinet Dessalegn Beza, Geta (…)2026-07-07
📄 medicine

Senhance-Assisted vs Laparoscopic Pediatric Nissen Fundoplication: A Single-Center Multidisciplinary Comparative Cohort Study from a German Tertiary Center

This single-center comparative cohort study demonstrates that Senhance®-assisted robotic Nissen fundoplication in children is a feasible and safe alternative to conventional laparoscopy, offering comparable surgical and anesthetic outcomes despite longer initial preparation times associated with the learning curve.

Daniel Levin Widmann, Isabel Kiesewetter, Matthias Kurz, Alexandra Schock, Oliver Muensterer, Jan Goedeke2026-07-07
📄 medicine

Neuropsychological and Autonomic Correlates of Chronic Stress in Dermatological Patients: A Comparative Analysis of GABAergic Therapy Regimens

This prospective study of 100 dermatological patients with chronic stress demonstrates that while both systemic and combined systemic-topical GABAergic therapies effectively restore autonomic balance and neuropsychological function, the combined approach may offer a potential advantage in accelerating the normalization of peripheral microcirculation and central neurodynamics.

A. S. Smitneva, I. V. Reverchuk¹, Svetlana Horemans2026-07-07