📄 Category

medicine

4810 papers

📄 medicine

Dramatic Improvement Followed by Rapid Deterioration after Glucocorticoid Pulse Therapy in a Case of Sporadic Creutzfeldt-Jakob Disease with Hashimoto's Encephalopathy Features: A Case Report

This case report describes a patient with sporadic Creutzfeldt-Jakob disease (CJD) who initially presented with Hashimoto's encephalopathy features and showed dramatic but transient improvement following glucocorticoid pulse therapy before rapid deterioration, ultimately confirming the CJD diagnosis through positive 14-3-3 protein and RT-QuIC assays.

Tianchen Wu, Yan Liang, Zhengzheng Wu, Jinbin Chen, Zhennian Zhang, Hui Yang2026-07-08
📄 medicine

Community-based malaria mass drug administration in a moderate transmission setting in Ghana: Pilot randomise control trial

This pilot cluster-randomized trial in rural Ghana demonstrates that nine rounds of community-based mass drug administration with artemether–lumefantrine significantly reduced malaria parasite prevalence by 94% and markedly improved anaemia outcomes, particularly among children under 15 years.

Ndong Ignatius Cheng, Chuo Ennestine Chu, Xue Wu, Ndong Henry Ndang, Brandon Nji Amambua-Ngwa, Nana Yaw Peprah, Keziah M (…)2026-07-08
📄 medicine

The Effect of Mindfulness-Based Stress Reduction Training Given to Young Girls Experiencing Fear of Childbirth on Fear of Childbirth, Coping Strategies with Stress, and State Anxiety Levels

This study demonstrates that a six-session Mindfulness-Based Stress Reduction (MBSR) training program significantly reduces fear of childbirth and state anxiety while improving stress coping strategies among young girls compared to a control group.

HACER UNVER KOCA, FADİME BİÇER ŞAHİN, ZEYNEP UNVER, LALE UNVER AYDIN, FUNDA KAVAK BUDAK2026-07-08
📄 medicine

Clinical and Biological Outcomes in School and Community-Based Sexual Health Interventions for Youth: An Umbrella Review

This umbrella review of 19 systematic reviews finds that while school and community-based sexual health interventions for youth aged 10–30 effectively improve knowledge, attitudes, and self-reported behaviors, they demonstrate limited impact on critical biological and clinical outcomes such as STI incidence, pregnancy rates, and viral load.

Salar Riyadh Jassim, Shaymaa Hadi Najm, Haider Nasser Jabber, Shukur Abdulkareem Mahmood, Atheer Amjad Rashad2026-07-08
📄 medicine

Integrative Oncology: a descriptive survey on healthcare providers of a tertiary cancer centre in Italy

This descriptive survey conducted at an Italian tertiary cancer center reveals that while a majority of healthcare providers lack formal training in Integrative Medicine, they demonstrate a strong interest in education and maintain a positive attitude toward caring for incurable patients, highlighting an urgent need for structured educational pathways to better support patient needs.

Romina Rossi, Todor Vassilev Paskov, Monia Dall’Agata, Lucia Angelini, Paola Cravero, Marianna Ricci, Margherita Currà (…)2026-07-08
📄 medicine

Effect of combined piperine and amoxicillin as an efflux pump inhibitor for metal-tolerant and antibiotic – resistant E. coli in broilers

This study demonstrates that combining the phytogenic bioenhancer piperine with amoxicillin effectively mitigates antibiotic resistance in metal-tolerant *E. coli* within broiler chickens by inhibiting efflux pumps, enhancing amoxicillin pharmacokinetics, and reducing heavy metal accumulation without compromising safety.

Reham A. Hosny, Amera F. Ebrahem, Mai F. Abdelaty, Amany Adel, Zeinab A. El-badiea, Mai A. Fadel2026-07-08
📄 medicine

Personalized 3D printing-assisted preoperative simulation surgery improves surgery outcomes and function recovery for complex tibial plateau fractures: a retrospective cohort study

This retrospective cohort study demonstrates that personalized 3D printing-assisted preoperative simulation significantly improves surgical efficiency, reduces intraoperative trauma and complications, and enhances long-term functional recovery for patients with complex tibial plateau fractures compared to conventional surgery.

Lugen Li, Chenpeng Zhang, Jinrong Liang, Xiao Wei, Zhengbo Hu2026-07-08
📄 medicine

Metformin for fatigue and cognitive dysfunction associated with postCOVID-19 condition and other suspected mitochondrial dysfunction: a case series

This case series reports that metformin rapidly improved severe fatigue and cognitive dysfunction in three women with post-COVID-19 condition or aromatase inhibitor-related symptoms, with symptom recurrence upon discontinuation and improvement upon re-initiation, suggesting a potential role for metformin in treating these syndromes linked to suspected mitochondrial dysfunction.

James E. Stahl2026-07-08
📄 medicine

Isatuximab-related uveal effusion in multiple myeloma: expanding the spectrum of anti-CD38 therapy ocular toxicity

This paper reports a case of bilateral acute angle closure caused by uveal effusion following isatuximab infusion in a multiple myeloma patient, highlighting a potentially underrecognized ocular toxicity of this anti-CD38 therapy that resolved with medical management.

Paula García-Valentín, Laura Sánchez Vela, Jaume Rigo Quera, Mercedes Gironella Mesa, Judith Ramirez Guerrero, Alba Jord (…)2026-07-08