📄 medicine

Association between a comprehensive governance strategy and the burden of urban non-traumatic multiple casualty incidents in China: a 14-year retrospective interrupted time-series study in Liuzhou, 2012-2025

This 14-year retrospective interrupted time-series study in Liuzhou, China, demonstrates that a citywide governance strategy implemented in January 2018 significantly reduced the burden of urban non-traumatic multiple casualty incidents, particularly carbon monoxide-related events, by effectively addressing seasonal peaks and preventable hazards.

Kangzhe Ruan, Yanmin Huang, Wei Huang, Dianyang Wang, Qiuyin Wei, Rongli Wei, Hailin Ruan, Yongchang Wei2026-07-08
📄 medicine

A MBene-based electrochemical aptasensor for label-free detection of EpCAM-overexpressing cancer cells

This study presents a label-free electrochemical aptasensor utilizing MBene nanosheets for the highly sensitive and specific detection of EpCAM-overexpressing cancer cells, demonstrating clinical viability through successful discrimination of malignant and benign endometrial samples.

Min Li, Yue Jiang, Yang Huang, Wei Chen, Yan Li, Dongxin Liang, Yuqi Wang, Qian Qie, Jiaxian Yuan, Jiahui Zhang, Yuan Zh (…)2026-07-08
📄 medicine

Prevalence of Sarcopenia and Associated Factors Among Elderly Individuals in Mbarara District, Southwestern Uganda

A cross-sectional study of 332 elderly individuals in Mbarara District, Uganda, found that 38.9% suffer from sarcopenia, a condition significantly associated with advanced age (80–89 years), malnutrition, and low loneliness, highlighting the urgent need for routine screening and targeted interventions.

Pius Ssembajjo, Julius Kyomya, Charles Nkubi Bagenda, Edgar Mugema Mulogo, Maria Tolley Sonia2026-07-08
📄 medicine

Epidemiology and prophylaxis status of leptospirosis cases presented to hospitals in Galle district in 2024

This 2024 study of 515 leptospirosis cases in Galle district, Sri Lanka, reveals that middle-aged male manual laborers and farmers are the most affected groups, with exposure to paddy fields and muddy land as primary risk factors, while highlighting a critical gap in preventive care due to extremely low chemoprophylaxis uptake.

PAA Chandrasiri, KM Somarathna, ED Hetttiarachchi, NP Wijamuni, VR Silva, DN Premarathna2026-07-08
📄 medicine

Health System Leadership and Maternal Healthcare Service Utilisation: A Mixed-Methods Study of Rural-Urban Inequities in Anambra State, Nigeria

This mixed-methods study in Anambra State, Nigeria, reveals that while transformational leadership positively influences maternal healthcare, rural-urban inequities and structural limitations result in low overall service utilization, with only 33.1% of women accessing the full continuum of care.

Silvia Isioma Ezemenahi, Chisom Sheila Ezemenahi, Anthonia Nkechiyem Alabi, Adebayo Ramat Yusuf, Uchenna Charles Ezemena (…)2026-07-08
📄 medicine

Parental Beliefs, Vaccine Hesitancy, and Refusal Factors Toward Routine Childhood Vaccination in Sana'a City, Yemen: A Cross-Sectional Study

This cross-sectional study of 467 parents in Sana'a, Yemen, reveals that while a majority complete routine childhood vaccinations, significant hesitancy persists due to safety concerns and misinformation, highlighting the need for targeted communication strategies and healthcare worker training.

Abol Gaith¹, Nabil Ahmed, Ghaida'a Hafedh, Aisha Faisal, Ahmed Hamood Al-Shahethi2026-07-08
📄 medicine

Mortality Risk Stratification of Hospitalized Community Acquired Pneumonia Patients Can be Supported by a Three-Tier, Blood Lactate Dehydrogenase Scale. A Retrospective Analysis of 14,883 Patients

This retrospective study of 14,883 hospitalized community-acquired pneumonia patients demonstrates that a three-tier blood lactate dehydrogenase (LDH) scale effectively stratifies mortality risk, with higher LDH levels significantly correlating with increased in-hospital and 30-day mortality rates as well as longer hospital stays.

Yehonatan Marziano, Marwa Sabih, Rani Abou Arishah, Majd Koskosi, Maria Firstov, Alisa Mazur, Gad Segal, Reut Kassif-Ler (…)2026-07-08
📄 medicine

A longitudinal qualitative study of fear of cancer recurrence in patients in breast cancer remission: phenomenology, change over time, and coping strategies

This longitudinal qualitative study of 28 breast cancer survivors reveals that fear of cancer recurrence is a dynamic, highly individualized experience triggered by diverse situational factors and managed through a wide array of coping strategies, underscoring the need for personalized psycho-oncological interventions.

Jan Christopher Cwik, Marie Bollmann, Rahel Kaesmacher, Sarah Buhl, Lusine Vaganian, Sonja Bussmann, Alexander L. Gerlac (…)2026-07-08
📄 medicine

Dynamic Characteristics of Myocardial Depression After Severe Bupivacaine-Induced Local Anesthetic Systemic Toxicity: A Case Report

This case report describes a patient who survived severe bupivacaine-induced myocardial depression requiring VA-ECMO support, highlighting a unique clinical trajectory characterized by a delayed functional nadir at 24 hours followed by a reversible recovery that was effectively monitored via serial echocardiography to guide weaning.

Shujian Zhang, Bingjie Lai, Yang Hu, Fuxi Ji, Qi Yang, Yongjie Yin, Jiakun Tian, Debiao Song2026-07-08