4814 papers
This multicenter randomized placebo-controlled trial suggests that daidzein-rich isoflavone aglycones (DRIAs) offer a safe, non-hormonal therapeutic option for endometriosis-associated dysmenorrhea, demonstrating a statistically significant pain reduction at Month 3 and a consistent trend toward efficacy without suppressing ovarian function.
This case-control study in Alborz Province, Iran, identifies several significant modifiable risk factors for childhood acute lymphoblastic leukemia, including maternal imaging during pregnancy and exposure to high-voltage power lines, and quantifies their substantial population-level impact to inform targeted preventive strategies.
This study demonstrates that in postmenopausal women, the protective effect of appendicular skeletal muscle index on bone mineral density is significant only in non-overweight/obese individuals and is attenuated by high BMI, while the influence of body composition on bone density exhibits distinct site-specific differences between the lumbar spine and femoral neck.
This retrospective cohort study of gastrointestinal surgery patients found that intraoperative Voluven administration was associated with a significantly reduced risk of anastomotic leakage without increasing the incidence of postoperative acute kidney injury or other complications compared to crystalloids alone.
This prospective study demonstrates that intraoperative Transit Time Flow Measurement (TTFM) parameters serve as significant predictors for perioperative myocardial infarction in OPCABG patients with diffuse coronary lesions and identifies Subcutaneous Vein Bypass Grafting (SCVBG) as a safer revascularization strategy than Endarterectomy (CE) for diffuse right coronary artery disease.
This cross-sectional study validates a questionnaire demonstrating that stigma and expected benefits, rather than cost concerns, are the primary psychosocial determinants of behavioral intention toward hearing aid uptake among adults.
This study demonstrates that elevated levels of NT-proBNP, GFAP, and HIF-1α in serum and cerebrospinal fluid are significantly associated with inflammatory injury and poor prognosis in patients with intracerebral hemorrhage, suggesting their potential clinical value as biomarkers for evaluating disease severity and outcomes.
This study employs a participatory action research approach in northwest England to map the social determinants and service gaps driving ketamine misuse among young people, ultimately proposing a collaborative prevention ecosystem that integrates community co-production with systemic responses to mitigate irreversible harms.
This study demonstrates that reduced size and altered morphology of deep cervical lymph nodes in Parkinson's disease patients correlate with impaired glymphatic function and disease severity, suggesting these lymph nodes serve as promising non-invasive biomarkers for assessing the condition.
This pilot study demonstrates that 3D multiscan stitching is technically feasible for generating standardized large-volume abdominal ultrasound datasets in phantoms, healthy volunteers, and patients with liver disease, enabling retrospective review and structured documentation while highlighting the need for further validation of geometric accuracy and diagnostic performance before broader clinical implementation.